Increased Serum Cu/Zn SOD in Individuals with Bipolar Disorder

Aim: To assess serum Cu/Zn SOD (Superoxide Dismutase) concentration in individuals with bipolar disorder. Subjects and methods: Serum from 20 individuals diagnosed with bipolar disorder and 20 age and gender similar controls were tested for Cu/Zn SOD serum concentration using ELISAs. Results: Serum Cu/Zn SOD levels of individuals with bipolar disorder were significantly higher than age and gender matched controls. Discussion: These results suggest an association between Cu/Zn SOD serum levels and bipolar disorder.