Silica sulfuric acid promoted one-pot synthesis of benzo[4,5]imidazo[1,2-a]pyrimidine derivatives under solvent-free conditions

A simple and efficient synthesis of benzo[4,5]imidazo[1,2-a]pyrimidine derivatives has been accomplished by the reaction of 2-aminobenzimidazole, aldehydes and β-dicarbonyl compounds under solvent-free conditions in the presence of silica sulfuric acid. KEY WORDS: Benzo[4,5]imidazo[1,2-a]pyrimidine, Silica sulfuric acid, 2-Aminobenzimidazole, Aromatic aldehydes, β-Dicarbonyl compounds, Solvent-free Bull. Chem. Soc. Ethiop. 2010, 24(3), 417-423.