In less than six months after infection, Erwinia amylovora may completely destroy a pome tree. This paper aims to increase awareness of the potential for developing plant protection strategies based on natural products. Since the damage caused by this bacterium are unrecoverable, we tested in vitro the effectiveness of a several plant extracts such as Salvia officinalis, Thymus serpyllum, Pelargonium odoratissimum, Hedera helix, Ocimum basilicum, Levisticum officinale, Tagetes patula, Galium verum and some pesticide products, on a strain of Erwinia amylovora isolated from the pomological collection of "Vasile Adamachi" farm, the University of Agricultural Sciences and Veterinary Medicine, Ia i. The strain was isolated from damaged pear shoots, after performing patogenicity test on immature pear fruits. Following the experiment conducted, copper oxychloride (Alcupral 50 PU) and Pelargonium odoratissimum showed a very good antibacterial activity against EA - A.P. strain.