Physical Activity and Cardiovascular Disease: Directions for Future Research

Regular physical activity is widely accepted as playing a crucial role in cardiovascular disease (CVD) prevention. However, despite extensive research in this field there are crucial gaps in our knowledge. This paper discusses future research directions including population subgroup-specific exercise doses, research in under represented populations, the role of cardiorespiratory fitness in predicting CVD risk, and novel biological mechanisms that might mediate the inverse association between physical activity and CVD risk.