Aplasia medular asociada al uso de ticlopidina: Report of one case

we report a 58 years old male that developed a bone marrow aplasia associated to the use of ticlopidine, prescribed after coronary artery stenting. the patient developed a pneumonia as a complication. he was admitted to the intermediate treatment unit, receiving wide spectrum antimicrobial therapy and a granulocyte colony stimulating factor (neupogen(r)) with favourable response. ticlodipine is an effective anti-platelet agent, but has serious hematological and other side effects. its prescription requires a close follow up and search for complications (rev méd chile 2002; 130: 798-802).