Antifungal activity of extracts and terpene constituents of aerial parts of Juniperus Lucayana

ethanolic and hexane extracts from the aerial parts of juniperus lucayana were assayed against the phytopathogenic fungus botrytis cinérea by the poisoned food technique. the hexane extract showed to have a higher antifungal activity than ethanolic extract. fractionation of hexane extract by silica gel open column chromatography and hplc afforded seven known compounds sandaracopimaric acid (1), 4-epi-dehydroabietic acid (2), oplopanone (3), oplodiol (4), nephtediol (5), 7α-hydroxycallitrisic acid (6), and 7-oxocallitrisic acid (7). compound 1 showed a significative fungal growth inhibition during the assay. the effect of compounds 2-7 on spore germination fungus was also studied.