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Fatores prognósticos e impacto da comorbidade na laringectomia fronto-lateral

DOI: 10.1590/S0100-69912009000500006

Keywords: larynx, laryngeal neoplasms, laryngectomy, comorbidity.

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Abstract:

objective: to evaluate the survival rates, comorbidity impact, complications, and treatment failure facts. methods: 38 patients clinically staged as t1b / t2n0m0 glottic tumors were analyzed. they underwent frontolateral laryngectomy with reconstruction, from january, 1995 to december, 2006. the oncological outcome, comobidity (through the adult comorbidity evaluation -27 ace-27 scale) and complications were studied and correlated to the demographic data and tumor characteristics. results: eight patients presented local recurrence being surgically salvaged. complications were not observed in 33 patients. there was no significant difference on the global and free of disease 5-year survival regarding the diverse comorbidity categories. only the pathological margins spread of the tumor presented significant difference on the global (p=0.0033) and free 0f disease survival (p<0.0001). conclusion: the 5-year global survival was 67.6% whereas the free of disease survival was 73.7%; the comorbidity did not represent independent prognostic factor; the postoperative complications rate was 13.2%; and only the pathological margin spread showed significant difference on the global and free of disease survival rates.

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