Perfil epidemiológico e fatores prognósticos no tratamento cirúrgico do adenocarcinoma de próstata clinicamente localizado

objective: radical prostatectomy remains the standard treatment for early prostate cancer. this study was conducted to evaluate the outcome and prognostic factors of radical prostatectomy. methods: a total of 500 patients with prostate cancer underwent radical prostatectomy at santa rita hospital- maringa-pr, between 2000 and 2006. clinical staging, preoperative prostate-specific antigen (psa) and gleason score were evaluated with pathological stage and margin status. follow-up psa monitoring and survival were analyzed. results: of 500 patients with clinical localized disease with a median follow up of 36,7±18,8 months. the average operative duration was 190± 45 minutes and the average intra-operative bleeding was 630 ml. the patients' preoperative serum psa was 7,8 ± 4,5 ng/dl , with a higher proportion of gleason score < 6(72%) and the tnm stage pt2c (65%). for late postoperative complications: incontinence in 2% and 46 % with erectile dysfunction. conclusion: radical prostatectomy in men shows excellent results. the chance of recurrence was directly associated with psa = 10 ng/ml, high gleason score and inversely proportional to age.