Enfermedad de Kikuchi-Fujimoto (linfadenitis histiocítica necrosante): Estudio clinicopatológico e inmunohistoquímico de 14 casos y su diagnóstico diferencial con otras linfadenitis necrosantes reactivas y neoplásicas

kikuchi-fujimoto disease also known as histiocytic necrotizing lymphadenopaty (hnl) is a rare entity, originally described in japanese population, although currently it has been described all over the world. it is more frequent in young women and it is usually located in cervical lymph nodes. we report 14 cases of hnl in mexican population, their clinicopathological and immunohistochemical study as well as a comparative study with other necrotizing lymphadenopaties due to b or t-cell lymphomas, tuberculosis, epstein barr virus infection, and non-specific necrosis. in our study we found that there was more expression of the immunomarkers cd68, mpo, cd123 and antikerat in oscar in the cases of hnl in contrast with the lesser or even null expression of the same markers in the necrotized lymph nodes of the comparative study group.