Detec？？o de metalo-beta-lactamase em Pseudomonas aeruginosa isoladas de pacientes hospitalizados em Goiania, Estado de Goiás

pseudomonas aeruginosa is a bacterium frequently isolated from hospital environments. this study had the aims of evaluating the susceptibility profile of pseudomonas aeruginosa previously isolated from patients in a hospital in goiania (goiás, brazil), performing phenotypic screening for metallo-beta-lactamase production and detecting its genes using the polymerase chain reaction technique. seventy-five 75 pseudomonas aeruginosa isolates were evaluated between january 2005 and january 2007. biochemical identification was performed using the api 20e？ system and an antibiogram was produced using the kirby-bauer method. among the 62 isolates that were resistant to imipenem and ceftazidime, 35 (56.4%) produced metallo-beta-lactamase, while 26 (74.3%) showed the blaspm-1 gene. the frequency of pseudomonas aeruginosa that produces metallo-beta-lactamase suggests that greater control over the dissemination of resistance in hospital environments is needed.