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Lagochilascaris minor: antibody production in experimentally infected mice

DOI: 10.1590/S0037-86822009000300016

Keywords: lagochilascaris minor, immunoglobulin g, immunoglobulin a, immunoglobulin m, serology.

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Abstract:

lagochilascaris minor is the causative agent of lagochilascariosis, a disease that affects the neck region and causes festering abscesses, with eggs, adult parasites and l3/l4 larvae within the purulent exudates. today, mice are considered to be intermediate hosts for the parasite. c57bl/6 mice produce immunoglobulin igm, iga and igg against the crude extract of the parasite; on the other hand, antibodies produced against the secreted/excreted antigens of lagochilascaris minor present lower levels of igm, iga and igg. this is the first description of antibody detection against different antigens of lagochilascaris minor.

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