Micoses sistêmicas: fatores associados ao óbito em pacientes com infec？？o pelo vírus da imunodeficiência humana, Cuiabá, Estado de Mato Grosso, 2005-2008

between 2005 and 2008, the prevalence of systemic mycosis among 1,300 hiv/aids patients in cuiabá, mato grosso, was 4.6%. the fungus species isolated were cryptococcus neoformans in 50%, cryptococcus gattii in 1.6%, cryptococcus spp in 6.6%, histoplasma capsulatum in 38.3% and paracoccidioides brasiliensis in 3.3%. death was recorded in the cases of 32 patients (53.3%), and cryptococcosis was the main cause. the cd4+ t lymphocyte count was low and similar among patients who survived or died due to systemic mycosis. the factors independently associated with the deaths of these patients were alcoholism (or: 8.2; 95% ci: 1.4-62.1; p = 0005) and the mean level of lactate dehydrogenase [758 (182) u/l vs. 416 (268) u/l; p < 0001]. the findings showed that systemic mycosis was highly lethal among the patients with hiv/aids in cuiabá and suggested that clinical-laboratory characteristics such as alcoholism and early elevation of lactate dehydrogenase may be factors relating to worse prognosis under these conditions.