| [1] | Arbeitman MN, Furlong EE, Imam F, Johnson E, Null BH, et al. (2002) Gene expression during the life cycle of Drosophila melanogaster. Science 297: 2270–2275.
|
| [2] | Christiansen AE, Keisman EL, Ahmad SM, Baker BS (2002) Sex comes in from the cold: the integration of sex and pattern. Trends Genet 18: 510–516.
|
| [3] | Burtis KC, Baker BS (1989) Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides. Cell 56: 997–1010.
|
| [4] | Ryner LC, Goodwin SF, Castrillon DH, Anand A, Villella A, et al. (1996) Control of male sexual behavior and sexual orientation in Drosophila by the fruitless gene. Cell 87: 1079–1089.
|
| [5] | Greenspan RJ, Ferveur JF (2000) Courtship in Drosophila. Annu Rev Genet 34: 205–232.
|
| [6] | Villella A, Gailey DA, Berwald B, Ohshima S, Barnes PT, et al. (1997) Extended reproductive roles of the fruitless gene in Drosophila melanogaster revealed by behavioral analysis of new fru mutants. Genetics 147: 1107–1130.
|
| [7] | Ito H, Fujitani K, Usui K, Shimizu-Nishikawa K, Tanaka S, et al. (1996) Sexual orientation in Drosophila is altered by the satori mutation in the sex-determination gene fruitless that encodes a zinc finger protein with a BTB domain. Proc Natl Acad Sci U S A 93: 9687–9692.
|
| [8] | Gailey DA, Hall JC (1989) Behavior and cytogenetics of fruitless in Drosophila melanogaster: different courtship defects caused by separate, closely linked lesions. Genetics 121: 773–785. Erratum, 122: 465.
|
| [9] | Anand A, Villella A, Ryner LC, Carlo T, Goodwin SF, et al. (2001) Molecular genetic dissection of the sex-specific and vital functions of the Drosophila melanogaster sex determination gene fruitless. Genetics 158: 1569–1595.
|
| [10] | Manoli DS, Foss M, Villella A, Taylor BJ, Hall JC, et al. (2005) Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour [see Comment]. Nature 436: 395–400.
|
| [11] | Demir E, Dickson BJ (2005) fruitless splicing specifies male courtship behavior in Drosophila [see Comment]. Cell 121: 785–794.
|
| [12] | Hildreth (1965) Doublesex, a recessive gene that transforms both males and females of Drosophila into intersexes. Genetics 51: 659–678.
|
| [13] | Taylor BJ, Villella A, Ryner LC, Baker BS, Hall JC (1994) Behavioral and neurobiological implications of sex-determining factors in Drosophila. Dev Genet 15: 275–296.
|
| [14] | Villella A, Hall JC (1996) Courtship anomalies caused by doublesex mutations in Drosophila melanogaster. Genetics 143: 331–344.
|
| [15] | Rideout EJ, Billeter JC, Goodwin SF (2007) The sex-determination genes fruitless and doublesex specify a neural substrate required for courtship song. Curr Biol 17: 1473–1478.
|
| [16] | Ditch LM, Shirangi T, Pitman JL, Latham KL, Finley KD, et al. (2005) Drosophila retained/dead ringer is necessary for neuronal pathfinding, female receptivity and repression of fruitless independent male courtship behaviors. Development 132: 155–164.
|
| [17] | Shirangi TR, Taylor BJ, McKeown M (2006) A double-switch system regulates male courtship behavior in male and female Drosophila melanogaster. Nat Genet 38: 1435–1439.
|
| [18] | Arbeitman MN, Fleming AF, Siegal ML, Null BH, Baker BS (2004) A genomic analysis of Drosophila somatic sexual differentiation and its regulation. Development 131: 2007–2021.
|
| [19] | Erdman SE, Chen HJ, Burtis KC (1996) Functional and genetic characterization of the oligomerization and DNA binding properties of the Drosophila doublesex proteins. Genetics 144: 1639–1652.
|
| [20] | An W, Wensink PC (1995) Three protein binding sites form an enhancer that regulates sex- and fat body-specific transcription of Drosophila yolk protein genes. EMBO J 14: 1221–1230.
|
| [21] | Burtis KC, Coschigano KT, Baker BS, Wensink PC (1991) The doublesex proteins of Drosophila melanogaster bind directly to a sex-specific yolk protein gene enhancer. EMBO J 10: 2577–2582.
|
| [22] | Drapeau MD, Radovic A, Wittkopp PJ, Long AD (2003) A gene necessary for normal male courtship, yellow, acts downstream of fruitless in the Drosophila melanogaster larval brain. J Neurobiol 55: 53–72.
|
| [23] | Dauwalder B, Tsujimoto S, Moss J, Mattox W (2002) The Drosophila takeout gene is regulated by the somatic sex-determination pathway and affects male courtship behavior. Genes Dev 16: 2879–2892.
|
| [24] | Lee G, Bahn JH, Park JH (2006) Sex- and clock-controlled expression of the neuropeptide F gene in Drosophila. Proc Natl Acad Sci U S A 103: 12580–12585.
|
| [25] | Straub T, Becker PB (2007) Dosage compensation: the beginning and end of generalization. Nat Rev Genet 8: 47–57.
|
| [26] | Storey JD (2002) A direct approach to false discovery rates. JR Statist Soc Ser B 64: 479–498.
|
| [27] | Qian HR, Huang S (2005) Comparison of false discovery rate methods in identifying genes with differential expression. Genomics 86: 495–503.
|
| [28] | Jung SH, Jang W (2006) How accurately can we control the FDR in analyzing microarray data? Bioinformatics 22: 1730–1736.
|
| [29] | Barnett T, Pachl C, Gergen JP, Wensink PC (1980) The isolation and characterization of Drosophila yolk protein genes. Cell 21: 729–738.
|
| [30] | Belote JM, Handler AM, Wolfner MF, Livak KJ, Baker BS (1985) Sex-specific regulation of yolk protein gene expression in Drosophila. Cell 40: 339–348.
|
| [31] | Fujii S, Amrein H (2002) Genes expressed in the Drosophila head reveal a role for fat cells in sex-specific physiology. EMBO J 21: 5353–5363.
|
| [32] | Brody T, Cravchik A (2000) Drosophila melanogaster G protein-coupled receptors. J Cell Biol 150: F83–F88.
|
| [33] | Deng X, Meller VH (2006) roX RNAs are required for increased expression of X-linked genes in Drosophila melanogaster males. Genetics 174: 1859–1866.
|
| [34] | Franke A, Baker BS (1999) The rox1 and rox2 RNAs are essential components of the compensasome, which mediates dosage compensation in Drosophila. Mol Cell 4: 117–122.
|
| [35] | Henry RA, Tews B, Li X, Scott MJ (2001) Recruitment of the male-specific lethal (MSL) dosage compensation complex to an autosomally integrated roX chromatin entry site correlates with an increased expression of an adjacent reporter gene in male Drosophila. J Biol Chem 276: 31953–31958.
|
| [36] | Kadener S, Villella A, Kula E, Palm K, Pyza E, et al. (2006) Neurotoxic protein expression reveals connections between the circadian clock and mating behavior in Drosophila. Proc Natl Acad Sci U S A 103: 13537–13542.
|
| [37] | Parisi M, Nuttall R, Edwards P, Minor J, Naiman D, et al. (2004) A survey of ovary-, testis-, and soma-biased gene expression in Drosophila melanogaster adults. Genome Biol 5: R40.
|
| [38] | Lazareva AA, Roman G, Mattox W, Hardin PE, Dauwalder B (2007) A role for the adult fat body in Drosophila male courtship behavior. PLoS Genet 3: e16. doi: 10.1371/journal.pgen.0030016.
|
| [39] | Lee G, Hall JC, Park JH (2002) Doublesex gene expression in the central nervous system of Drosophila melanogaster. J Neurogenet 16: 229–248.
|
| [40] | Radovic A, Wittkopp PJ, Long AD, Drapeau MD (2002) Immunohistochemical colocalization of Yellow and male-specific Fruitless in Drosophila melanogaster neuroblasts. Biochem Biophys Res Commun 293: 1262–1264.
|
| [41] | Barmina O, Gonzalo M, McIntyre LM, Kopp A (2005) Sex- and segment-specific modulation of gene expression profiles in Drosophila. Dev Biol 288: 528–544.
|
| [42] | Ekengren S, Hultmark D (2001) A family of Turandot-related genes in the humoral stress response of Drosophila. Biochem Biophys Res Commun 284: 998–1003.
|
| [43] | Uttenweiler-Joseph S, Moniatte M, Lagueux M, Van Dorsselaer A, Hoffmann JA, et al. (1998) Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry study. Proc Natl Acad Sci U S A 95: 11342–11347.
|
| [44] | Dennis G Jr., Sherman BT, Hosack DA, Yang J, Gao W, et al. (2003) DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol 4: P3.
|
| [45] | Taylor BJ, Truman JW (1992) Commitment of abdominal neuroblasts in Drosophila to a male or female fate is dependent on genes of the sex-determining hierarchy. Development 114: 625–642.
|
| [46] | Finley KD, Taylor BJ, Milstein M, McKeown M (1997) dissatisfaction, a gene involved in sex-specific behavior and neural development of Drosophila melanogaster. Proc Natl Acad Sci U S A 94: 913–918.
|
| [47] | Erdman SE, Burtis KC (1993) The Drosophila doublesex proteins share a novel zinc finger related DNA binding domain. EMBO J 12: 527–535.
|
| [48] | Coschigano KT, Wensink PC (1993) Sex-specific transcriptional regulation by the male and female doublesex proteins of Drosophila. Genes Dev 7: 42–54.
|
| [49] | Abrahamsen N, Martinez A, Kjaer T, Sondergaard L, Bownes M (1993) Cis-regulatory sequences leading to female-specific expression of yolk protein genes 1 and 2 in the fat body of Drosophila melanogaster. Mol Gen Genet 237: 41–48.
|
| [50] | Cho S, Wensink PC (1996) Purification and physical properties of the male and female double sex proteins of Drosophila. Proc Natl Acad Sci U S A 93: 2043–2047.
|
| [51] | Li H, Baker BS (1998) hermaphrodite and doublesex function both dependently and independently to control various aspects of sexual differentiation in Drosophila. Development 125: 2641–2651.
|
| [52] | Ahmad SM, Baker BS (2002) Sex-specific deployment of FGF signaling in Drosophila recruits mesodermal cells into the male genital imaginal disc. Cell 109: 651–661.
|
| [53] | Garrett-Engele CM, Siegal ML, Manoli DS, Williams BC, Li H, et al. (2002) intersex, a gene required for female sexual development in Drosophila, is expressed in both sexes and functions together with doublesex to regulate terminal differentiation. Development 129: 4661–4675.
|
| [54] | Martin JH, Benzer S, Rudnicka M, Miller CA (1993) Calphotin: a Drosophila photoreceptor cell calcium-binding protein. Proc Natl Acad Sci U S A 90: 1531–1535.
|
| [55] | Yang Y, Ballinger D (1994) Mutations in calphotin, the gene encoding a Drosophila photoreceptor cell-specific calcium-binding protein, reveal roles in cellular morphogenesis and survival. Genetics 138: 413–421.
|
| [56] | Ballinger DG, Xue N, Harshman KD (1993) A Drosophila photoreceptor cell-specific protein, calphotin, binds calcium and contains a leucine zipper. Proc Natl Acad Sci U S A 90: 1536–1540.
|
| [57] | Claridge-Chang A, Wijnen H, Naef F, Boothroyd C, Rajewsky N, et al. (2001) Circadian regulation of gene expression systems in the Drosophila head. Neuron 32: 657–671.
|
| [58] | McDonald MJ, Rosbash M (2001) Microarray analysis and organization of circadian gene expression in Drosophila. Cell 107: 567–578.
|
| [59] | Ceriani MF, Hogenesch JB, Yanovsky M, Panda S, Straume M, et al. (2002) Genome-wide expression analysis in Drosophila reveals genes controlling circadian behavior. J Neurosci 22: 9305–9319.
|
| [60] | Sakai T, Ishida N (2001) Circadian rhythms of female mating activity governed by clock genes in Drosophila. Proc Natl Acad Sci U S A 98: 9221–9225.
|
| [61] | Kyriacou CP, Hall JC (1980) Circadian rhythm mutations in Drosophila melanogaster affect short-term fluctuations in the male's courtship song. Proc Natl Acad Sci U S A 77: 6729–6733.
|
| [62] | Tauber E, Roe H, Costa R, Hennessy JM, Kyriacou CP (2003) Temporal mating isolation driven by a behavioral gene in Drosophila. Curr Biol 13: 140–145.
|
| [63] | Stockinger P, Kvitsiani D, Rotkopf S, Tirian L, Dickson BJ (2005) Neural circuitry that governs Drosophila male courtship behavior [see Comment]. Cell 121: 795–807.
|
| [64] | Lee G, Foss M, Goodwin SF, Carlo T, Taylor BJ, et al. (2000) Spatial, temporal, and sexually dimorphic expression patterns of the fruitless gene in the Drosophila central nervous system. J Neurobiol 43: 404–426.
|
| [65] | Goodwin SF, Taylor BJ, Villella A, Foss M, Ryner LC, et al. (2000) Aberrant splicing and altered spatial expression patterns in fruitless mutants of Drosophila melanogaster. Genetics 154: 725–745.
|
| [66] | Jin W, Riley RM, Wolfinger RD, White KP, Passador-Gurgel G, et al. (2001) The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster [see Comment]. Nat Genet 29: 389–395.
|
| [67] | Ranz JM, Castillo-Davis CI, Meiklejohn CD, Hartl DL (2003) Sex-dependent gene expression and evolution of the Drosophila transcriptome. Science 300: 1742–1745.
|
| [68] | Usui-Aoki K, Ito H, Ui-Tei K, Takahashi K, Lukacsovich T, et al. (2000) Formation of the male-specific muscle in female Drosophila by ectopic fruitless expression [see Comments]. Nat Cell Biol 2: 500–506.
|
| [69] | Kean L, Cazenave W, Costes L, Broderick KE, Graham S, et al. (2002) Two nitridergic peptides are encoded by the gene capability in Drosophila melanogaster. Am J Physiol Regul Integr Comp Physiol 282: R1297–R1307.
|
| [70] | Davies SA, Huesmann GR, Maddrell SH, O'Donnell MJ, Skaer NJ, et al. (1995) CAP2b, a cardioacceleratory peptide, is present in Drosophila and stimulates tubule fluid secretion via cGMP. Am J Physiol 269: R1321–R1326.
|
| [71] | Hewes RS, Taghert PH (2001) Neuropeptides and neuropeptide receptors in the Drosophila melanogaster genome. Genome Res 11: 1126–1142.
|
| [72] | Thomas PD, Campbell MJ, Kejariwal A, Mi H, Karlak B, et al. (2003) PANTHER: a library of protein families and subfamilies indexed by function. Genome Res 13: 2129–2141.
|
| [73] | Mi H, Vandergriff J, Campbell M, Narechania A, Majoros W, et al. (2003) Assessment of genome-wide protein function classification for Drosophila melanogaster. Genome Res 13: 2118–2128.
|
| [74] | Towers PR, Sattelle DB (2002) A Drosophila melanogaster cell line (S2) facilitates post-genome functional analysis of receptors and ion channels. Bioessays 24: 1066–1073.
|
| [75] | Kimura K, Ote M, Tazawa T, Yamamoto D (2005) Fruitless specifies sexually dimorphic neural circuitry in the Drosophila brain. Nature 438: 229–233.
|
| [76] | Wolfner MF (2003) Sex determination: sex on the brain? Curr Biol 13: R101–R103.
|
| [77] | Nakamura M, Baldwin D, Hannaford S, Palka J, Montell C (2002) Defective proboscis extension response (DPR), a member of the Ig superfamily required for the gustatory response to salt. J Neurosci 22: 3463–3472.
|
| [78] | Manoli DS, Baker BS (2004) Median bundle neurons coordinate behaviours during Drosophila male courtship. Nature 430: 564–569.
|
| [79] | Stocker RF (1994) The organization of the chemosensory system in Drosophila melanogaster: a review. Cell Tissue Res 275: 3–26.
|
| [80] | Wang Z, Singhvi A, Kong P, Scott K (2004) Taste representations in the Drosophila brain. Cell 117: 981–991.
|
| [81] | Thorne N, Chromey C, Bray S, Amrein H (2004) Taste perception and coding in Drosophila. Curr Biol 14: 1065–1079.
|
| [82] | Murphey RK, Possidente D, Pollack G, Merritt DJ (1989) Modality-specific axonal projections in the CNS of the flies Phormia and Drosophila. J Comp Neurol 290: 185–200.
|
| [83] | Lienhard MC, Stocker RF (1987) Sensory projection patterns of supernumerary legs and aristae in D. melanogaster. J Exp Zool 244: 187–201.
|
| [84] | von Schlichet F, Hall JC (1979) Neural topography of courtship song in sex mosaics of Drosophila melanogaster. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 129: 85–95.
|
| [85] | Kulkarni SJ, Steinlauf AF, Hall JC (1988) The dissonance mutant of courtship song in Drosophila melanogaster: isolation, behavior and cytogenetics. Genetics 118: 267–285.
|
| [86] | Terhzaz S, Rosay P, Goodwin SF, Veenstra JA (2007) The neuropeptide SIFamide modulates sexual behavior in Drosophila. Biochem Biophys Res Commun 352: 305–310.
|
| [87] | Jordan KW, Carbone MA, Yamamoto A, Morgan TJ, Mackay TF (2007) Quantitative genomics of locomotor behavior in Drosophila melanogaster. Genome Biol 8: R172.
|
| [88] | Sarov-Blat L, So WV, Liu L, Rosbash M (2000) The Drosophila takeout gene is a novel molecular link between circadian rhythms and feeding behavior. Cell 101: 647–656.
|
| [89] | Dierick HA, Greenspan RJ (2006) Molecular analysis of flies selected for aggressive behavior. Nat Genet 38: 1023–1031.
|
| [90] | Shalon D, Smith SJ, Brown PO (1996) A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization. Genome Res 6: 639–645.
|
| [91] | Rouillard JM, Zuker M, Gulari E (2003) OligoArray 2.0: design of oligonucleotide probes for DNA microarrays using a thermodynamic approach. Nucleic Acids Res 31: 3057–3062.
|
| [92] | Cherbas L, Bogart K, Zhou Y, Cherbas P, Andrews J (2006) DGRC-2: Spotted oligonucleotide transcriptome microarrays for the Drosophila community. CGB Technical Report 2006–01: 1–12.
|
| [93] | Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, et al. (2004) Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 5: R80.
|
| [94] | Yang YH, Dudoit S, Luu P, Lin DM, Peng V, et al. (2002) Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res 30: e15.
|
| [95] | Faul F, Erdfelder E, Lang A, Buchner A (1996) G*Power3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39: 175–191.
|
| [96] | Peirson SN, Butler JN, Foster RG (2003) Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis. Nucleic Acids Res 31: e73.
|
