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Influência de fatores maternos e neonatais no desenvolvimento da displasia broncopulmonar

DOI: 10.1590/S0104-42302011000400012

Keywords: bronchopulmonary dysplasia, premature newborns, mechanical ventilation, oxygen therapy, risk factors.

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Abstract:

objective: to review epidemiological features of bronchopulmonary dysplasia (bpd) and its relationship with maternal and neonatal conditions in a neonatal unit. methods: cross-sectional, descriptive and analytical study involving preterm newborns (nbs) with a birth weight lower than 1,500 g and gestational age under 37 weeks. data was collected through a review of medical records of these newborns admitted to a neonatal unit. results: the study included 323 newborns with a mean birth weight of 1,161 g (± 231 g), gestational age between 24 and 36.5 weeks, with a bpd incidence of 17.6%. among the nbs developing bpd, the mean of days using invasive mechanical ventilation (imv), non-invasive ventilation (nimv), and supplemental oxygen was 17.6, 16.2, and 46.1 days, respectively, with a time significantly longer for those nbs developing bpd (p < 0.001). bpd occurred significantly more often in nbs with a patent ductus arteriosus (pda). conclusion: bpd incidence in this study was similar to that found in the literature. no bpd association with maternal infection and antenatal corticosteroid use was found. nbs receiving exogenous surfactant had a higher bpd incidence because they had lower bw and ga. concomitant occurrence of pda and bpd is associated with staying longer on imv, nimv and supplemental oxygen

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