Síndrome de Seckel, Dos Casos en una Familia Colombiana

seckel syndrome is an infrequent autosomic recessive genetic disorder. it is characterized by short stature, mental retardation and a typical facies. nearly 10 families have been reported with two or more affected members.this paper reports two sisters, daughters of non-related parents. the mother presented bilateral fissurate lip. the main traits of this syndrome are highlighted through a literature review.