El litio y su influencia en la función tiroidea

lithium, used as a first line treatment in maniac depression disease, affects the thyroid gland function. in the last papers published between 1999 and 2007, it has been found a high prevalence of hypothyroidism in bipolar patients, especially in females and when starting lithium at a later age. the duration of treatment and lithemia seams to have no correlation with the begining of hypothyroidism. because of the poor literature written about this issue, the aim of this review is to update the last papers published.