Linfoma no Hodgkin secundario a inmunosupresión por transplate renal tratado con quimioterapia

objective: the posterior transplant lymph syndrome proliferative disorders include a group of renal lymphoid diseases by definition are present after a solid organ transplant or in bone marrow and are related to immunosuppressive therapy administered. the likelihood of developing a malignancy renal transplant recipient followed over the 17 years is 14 % for the non-skin cancers, 47 % in the carcinomas of the skin and 55 % for any type of cancer. method: in this work we describes a rare case of a 40 year old patient with chronic renal failure secondary to arterial hypertension in hemodialysis, who underwent cadaveric renal transplant in 2007, the patient presented impaired renal function with palpable mass in right iliac fosse, in treatment with immune suppressants. results: the histopathology examination of the biopsy reported, posterior transplant with lymphoproliferative disorder with immunohistochemistry positive for cd20, cd79 on b lymphoid cells and cd45 on t lymphoid cells, the extension studies concluding that the mediastinal metastases were: non-hodgkin？s lymphoma immunophenotyping b extranodal cd20 + stage iv renal with metastases in the superior mediastinum ipi score may/2009 classified how secondary to high risk renal transplantation. the patient was treated with r-chop we obtained a oncology complete response, as demonstrated by ct-pet, and currently free of disease, in nephrology controls. conclusion: it should monitor any clinical manifestation in the treatment of this kind of patients and served as a rejection of transplant can be confused with metastatic brain tumor.