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Estudio toxicológico del extracto acuoso obtenido del duramen de Enterolobium cyclocarpum (Jacq.) Griseb.

Keywords: ic50/lc50, crustacean, termite, rat, bacteria, fungus, oomicet, mcf-7 cells.

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Abstract:

rationale: a protective effect of the aqueous extract from enterolobium cyclocarpum (jacq.) griseb duramen on pinewood was reported. it was also attributed anti-nutritional and repellent action against dry wood termites incisitermes marginipennis (latreillé); it is considered a potential candidate for perishable dry wood preservation, whose possible toxicity must be studied. objectives: to determine the toxicity of aqueous extract from e. cyclocarpum duramen. methods: mean inhibitory and lethal concentrations (ic50/lc50) of an aqueous extract from e. cyclocarpum duramen in organisms from different trophic levels. results: lc50 for artemia salina crustacean, i. marginipennis termite and wistar rat were 1,3; 2 mg/ml and over 2 000 mg/kgind respectively. in microbial isolates, ic50 was 300 mg. in mcf-7 tumor cell line, ic50 was 1,3 mg. conclusions: when comparing observed ic50/lc50 with allowable toxicity limits, it was concluded that the extract under study was not toxic for these organisms.

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