Marco de trabajo fenomenológico para el da？o del cartílago articular

in present paper it is supposed the lack of articular cartilage by chondrocytes death leading to a loss of extracellular matrix. given that the articular cartilage is avascular, chondrocytes viability may be one of the critical factors limiting the repair response. in present article is exposed a damage model due to cartilaginous tissue fatigue, similar to that used in metals, where it is considered that any load varying in time may provokes a fatigue failure caused by damage accumulation by repetitive efforts. likewise, in the case of cartilage, tissue damage is produced by cellular death in presence of repeated loads in time. computation simulations were performed in agreement with clinical and experimental results obtained on cartilage damage.