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Aminoglucósidos: mirada actual desde su historiaKeywords: aminoglycosides, efficacy, one-dose, resistance, toxicity, synergism, monotherapy, combined therapy. Abstract: we referred to history, mechanisms of action and efficacy of aminoglycosides in pediatric patients as well as limitations in their use because of the emergence of bacterial resistance caused by overuse. the one-dose administration strategy as an alternative to the traditional methods of fractioned doses, the most frequent and serious complictions of aminoglycosides and their sinergism with other antimicrobial families were presented. we quoted research studies on antibiotic therapy made in the country.
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