Trastornos de la hemostasia durante la gestación

a literature review was performed in relation to hemorrhagic disorders during pregnancy signaling the physiologic and hematologic changes occurring at pregnancy and the puerperium. the well-known theory of coagulation as a cascade process has not validity at present time, but that this one gave way to the modern cellular theory of coagulation. the diagnostic and therapeutical in blood incoagulability obstetrics hemorrhages (bioh). analyzing the clinical picture and the lab results, it is possible to make an accurate diagnosis of present biohs. the blood platelet decrease, frequently in bioh cases is the first alteration, the v coagulation factor, in general is always decreased, whereas the viii coagulation factor is in general increased. the high and low weight heparin use and of coagulation factors for treatment of biohs has been controversial. in such cases it is recommended the administration of fresh blood, fresh plasma, the homologous plasma cryoprecipitates and platelet concentrates. nowadays these therapeutical behaviors have been replaced by the use of recombinant fviia, which may be associated with the misoprostol. the uterine cavity evacuation as soon as possible is a needed measure in some patients.