Efectos sistémicos de la aplicación del n-butil 2-cianoacrilato en la microcirugía vascular experimental

the usefulness of n-butyl 2-cyanoacrylate in vascular microsurgery was assessed, the evolution in the closure of vascular wounds was compared, and the visceral and hematological behaviour was analysed. a cohort randomized prospective study was performed (1 and 6 months) in 65 male wistar rats: sound controls (n= 10), study (n= 28), and positive controls (n= 27). cyanoacrylate was applied in the abdominal aorta using three retention stitches. the evolution was compared with the classic suture with polypropylene 8/0. the histological, visceral, and blood repercussion was studied. there was a similar evolution by using both methods. degradation of cyanoacrylate was observed at 6 months. the utilization of the adhesive neither influence on the evolution of the cases, nor produce toxicity.