Sarcoidosis una granulomatosis sistémica de etiología no definida: a non-defined systemic granulomatosis

sarcoidosis is a multisystem disease including the granulomatous affections, characterized by presence of non-caseinogen granulomas in involved organs. it has a universal distribution and until now hasn't been isolated any responsible agent. diagnosis was based on in a combination of clinical and radiological picture with the presence of non-caseinogen granulomas in tissues where the cultures for mycobacteria and fungi, able to produce a similar clinical and pathologic histology picture were negatives. due to heterogeneity of clinical manifestations, the uncertain clinical course and the medication potential adverse effects of, to difficult its management. patients are seen without treatment due to possibility of a spontaneous cure. steroids are the basis of sarcoidosis treatment and with the available technology maybe in next decade increase our knowledge of this disease as well as a specific therapy.