Evaluación a largo plazo de la esplenectomía parcial en pacientes con esferocitosos hereditaria

the effectiveness of partial splenomegalia (ps) was assessed in 17 patients with hereditary spherocytosis seen in the hematology and immunology institute. age at diagnosis was of 6.71 ± 5.38 months. all of them had splenomegalia. a patient had vesicular lithiasis before intervention. criteria to presence of splenomegalia were: transfusion requirements (822.4 %), chronic anemia and splenomegalia (11.7 %) and splenomegalia (5.9 %). age at moment of ps was of 7.0 ± 2.6 years. hemoglobin (hb) was low in the 94.1 % of patients; reticulocytes increased in the 100 % and the total and indirect bilirubin was high in the 76.5 % and the 88.2 %, respectively. current mean age of patients is 16.24 ± 4.26 years with a course time of 9.24 ± 4.47 years. postoperative laboratory variables showed a significant increase of hb (p= 4 × 10-9) and a decrease of reticulocytes (p= 0.003). trend in time of hb remained stable in levels achieved after intervention in all patients with more than 10 years of operated on, but not for reticulocytes. two patients showed a growing of splenic fragment; one was associated with a poor clinical-hematological response. there not sepsis or thromboembolism complications after procedure.