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OALib Journal期刊
ISSN: 2333-9721
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Expresión fenotípica de las moléculas CD5 y CD6 en la leucemia linfoide crónica B-CD5+

Keywords: cd5 and cd6 molecules, llc-b- cd5+, flow cytometry..

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Abstract:

cd5 and cd6 molecules have a co-stimulant function and show homology in structure. we assessed cd6 molecule expression using anti-cd6 (t1) monoclonal antibody in the cellular immunophenotyping from patients presenting b chronic lymphoid leukemia, and it was compared to cd5 molecule expression. results show a homology in phenotype expression of both molecules (cd5 and cd6), what associated with the fact that both lymphocyte receptors are physically linked, allow to suggest that cd6 molecule is a interesting biological marker in prognosis assessment, and the possibility of new therapeutic variants in this disease.

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