Bases moleculares e importancia clínica de los excepcionales fenotipos de grupo sanguíneo P y P K

all the cells of the individuals with phenotypes "p" y "pk" lack the glucidic antigens of "public" blood groups. these subjects form natural and regular antibodies against the missing structures (anti-p, anti-pp1 y anti-pp1pk) that agglutínate or hemolyze the red-blood cells of every individual, excepting those with the same phenotype. due to the exceptional character of these pictures (a few individuals per million) and their association with severe transfusional hemolytic reactions and repeated miscarriages, these subjects should be identified and characterized