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Hipertensión pulmonar en el adulto con anemia drepanocítica. Resultados preliminares

Keywords: sickle cell disease, lactic dehydrogenase, pulmonary hypertension.

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Abstract:

a total of 104 adult patients presenting with sickle cell disease were assessed and classified into: group 1 (g1) patients without pulmonary hypertension (pht) (n = 74) and group 2 (g2) patients with pht (n = 30). there was a statistically significant decrease for hemoglobin, hematocrit and pulse oximeter and a significant increase of leukocytes, the lactic dehydrogenase, the total and indirect bilirubin, la mb creatine kinase and the creatinine in the g2-patients. the x2 test demonstrate a significant difference among groups for the acute thoracic syndrome (p = 0,05) more frequent in the g2. the pht frequency in all patients assessed was of 28,8%. the ventricular extrasystoles were the more frequent alterations in the electrocardiogram in the g1 and the left ventricle hypertrophy in the g2; whereas in the doppler echocardiogram the more frequent as the left ventricle dilatation in both groups. from the cases diagnosed with pht (n = 30), 27 (73,3%) were classified as 1 degree; 7 (23,3%) 2 and 1 degrees (3,4%) 3 degree.

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