Validación de la técnica para la determinación de catequina en tabletas de Rhizophora mangle L. por CLAR

authors made the high-performance liquid chromatography method validation to the quantitative assessment of cathechin as a marker substance in tablets obtained from the bark of rhizophora mangle l. dry extract used in gastroduodenal ulcers treatment. considering that this method as such is classified to quantitative assessment of the major compound or active ingredient in formulae or raw material, the following parameters were assessed : linearity, accuracy, sensitivity and precision expressed in its two ways: repetition and intermediate precision. results obtained showed that this method is reliable allowing the compound assessment in presence of other substances, including excipients and auxilliary substances and to detect the presence of degradation products. also, the statistical processing of results evidenced the linearity, precision, sensitivity and accuracy of this method.