全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

Validation of an analytical methodology by gas chromatography for the assay of barbiturates in blood samples

Keywords: barbiturates, gas chromatography, forensic samples, validation, flame ionization detector.

Full-Text   Cite this paper   Add to My Lib

Abstract:

an analytical methodology was developed for the quantitative assay of phenobarbital, pentobarbital and butobarbital in blood samples, using aprobarbital as an internal standard. after sample cleaning by liquid-liquid extraction, the separation was achieved by liquid gas chromatography using a capillary column in pulsed splitless mode, temperature ramp, and helium as carrier gas and flame ionization detector. the methodology was selective, linear, precise and accurate. the linearity was adequate, between 20 and 100 mcg/ml, for all of three barbiturates studied. the developed methodology was applied in two forensic cases presented in the toxicology lab of the national institute of legal medicine and forensic sciences in bogotá.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133