Desenvolvimento e valida？？o de um método analítico para quantifica？？o por espectroscopia UV de captopril em comprimidos de libera？？o prolongada

an analytical method using an ultraviolet spectroscopy (uv) was developed and validated to quantify the drug captopril in tablets of delayed release. the available parameters were: specificity, linearity and range, precision, accuracy and robustness. the linearity in the range of 5.0 - 40.0 μg/ml presented a correlation coefficient of 0, 9998. the excipients in the formulation did not interfere with the analysis and the recovery was quantitative 100, 20 ± 0, 28%. all results were satisfactory and the method proved to be adequate to quantify captopril in delayed release tablets.