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Compara??o entre três escores embrionários como fator prognóstico do sucesso em fertiliza??o in vitro

DOI: 10.1590/S0100-72032003000300006

Keywords: embryo score, in vitro fertilization, pregnancy rate, implantation rate.

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Abstract:

purpose: to evaluate three embryo scoring systems specific for 3-day embryos and to correlate them with positive in vitro fertilization outcome. method: retrospective study of the in vitro fertilization program of the university hospital, faculty of medicine of ribeir?o preto, university of s?o paulo. a total of 137 patients submitted to the transfer of 439 embryos were evaluated. the main outcomes measured were pregnancy and implantation rates. results: a significant difference in the three scoring systems was observed between pregnant (n=53) and non-pregnant (n=84) patients (p<0.0001). in the first embryo scoring system, in which cell number alone was used, higher pregnancy (70%) and implantation rates (42%) were observed when embryos with a mean blastomere number higher than 8 were transferred. scoring system 2, based on a total four-point score (cleavage stage, blastomere number, fragmentation and symmetry), showed increased pregnancy (52.8%) and implantation rates (31%) for scores above 2. scoring system 3, based on cell number and morphological criteria, also showed higher pregnancy and implantation rates with increasing average scores of the transferred embryos. conclusion: the three scoring systems assessed in 3-day embryos were positively correlated with pregnancy and implantation rates.

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