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Nódulo umbilical metastático (nódulo da Irm? Maria José): um sinal de alerta para tumora??o maligna intra-abdominal - relato de casoDOI: 10.1590/S0100-72032003000600011 Keywords: umbilical metastatic tumor, sister mary joseph's nodule, ovarian neoplasms. Abstract: the umbilical metastatic tumoral nodule, sister mary joseph's nodule, is a rare clinical sign indicative of disseminated intra-abdominal tumor, and may be the first evidence of malignancy. the authors report a case of a patient with umbilical metastatic nodule in whom the diagnosis of the primary tumor was possible by immunohistochemistry of the lesion biopsy.
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