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Administra??o oral de peptídios e proteínas: I. Estratégias gerais para aumento da biodisponibilidade oral

DOI: 10.1590/S1516-93322002000200002

Keywords: absorption enhancer, formulation, microencapsulation, peptide drugs, protease inhibitors.

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Abstract:

there are hundreds of peptides and proteins clinically relevant. the difficulties associated with their oral administration have been responsible for the major efforts in developing ways to improve oral bioavailability. both these subjects are described in this review. the potentiality of microencapsulation presents this technique as a privileged approach for the oral delivery of peptide and protein drugs.

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