Avalia？？o clínica e da espessura cutanea um ano após preenchimento de ácido hialur？nico

background: few scientific studies evaluate the durability of existent fillers with objective parameters and non invasive methods. the objective of this study was to evaluate durability of a hyaluronic acid formula (derma hyal ？) in the nasolabial fold treatment, comparing the perception of clinical effect and soft tissue thickness measured by ultrasound. methods: ten women were treated. evaluation was made before, after 1, 3, 6, 9 and 12 months, clinically and by ultrasound. results: median ultrasound thickness was 0.38 ± 0.14 pre, 0.69 ± 0.19 after 1 month, 0.65 ± 0.17 after 3 months, 0.61 ± 0.22 after 6 months, 0, 57 ± 0.23 after 9 months and 0.55 ± 0.14 after 12 months. data analyzed by friedman's test were not statistically significant. regarding patient satisfaction after 6 months, 3 considered the results unsatisfactory, 5 fairly satisfactory and 2 satisfactory. only one patient considered the treatment satisfactory at 9 months. by 12 months one considered it fairly satisfactory and nine unsatisfactory. all patients said they would do treatment again in another opportunity. conclusions: ultrasound evaluation of dermal thickness after filler treatment proved to be an objective and non invasive method, since when associated with clinical examination. increase in soft tissue thickness was demonstrated until 12 months after nasolabial fold injection, with progressive decrease after this period. despite the increase in soft tissue thickness at ultrasound, it was not statistically significant. clinical effect was noticed by patients until nine months after treatment with this product.