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Trials

ISSN Print: 1745-6215

ISSN Online:

主页: http://www.trialsjournal.com

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The ACCESS study a Zelen randomised controlled trial of a treatment package including problem solving therapy compared to treatment as usual in people who present to hospital after self-harm: study protocol for a randomised controlled trial

Simon Hatcher, Cynthia Sharon, Allan House, Sunny Collings, Varsha Parag, Nicola Collins

Application of adaptive design and decision making to a phase II trial of a phosphodiesterase inhibitor for the treatment of intermittent claudication

Roger J Lewis, Jason T Connor, John R Teerlink, James R Murphy, Leslie T Cooper, William R Hiatt, Eric P Brass

When is informed consent required in cluster randomized trials in health research?

Andrew D McRae, Charles Weijer, Ariella Binik, Jeremy M Grimshaw, Robert Boruch, Jamie C Brehaut, Allan Donner, Martin P Eccles, Raphael Saginur, Angela White, Monica Taljaard

Acupuncture as analgesia for low back pain, ankle sprain and migraine in emergency departments: Study protocol for a randomized controlled trial

Marc Cohen, Shefton Parker, David Taylor, De Villiers Smit, Michael Ben-Meir, Peter Cameron, Charlie Xue

Peer support for family carers of people with dementia, alone or in combination with group reminiscence in a factorial design: study protocol for a randomised controlled trial

Georgina Charlesworth, Karen Burnell, Jennifer Beecham, Zo？ Hoare, Juanita Hoe, Jennifer Wenborn, Martin Knapp, Ian Russell, Bob Woods, Martin Orrell

Effect of additional treatment with EXenatide in patients with an Acute Myocardial Infarction (EXAMI): study protocol for a randomized controlled trial

Martijn Scholte, Leo Timmers, Flip JP Bernink, Robert N Denham, Aernout M Beek, Otto Kamp, Michaela Diamant, Anton JG Horrevoets, Hans WM Niessen, Weena JY Chen, Albert C van Rossum, Niels van Royen, Pieter A Doevendans, Yolande Appelman

A randomised controlled trial of probiotics for the prevention of spontaneous preterm delivery associated with bacterial vaginosis: preliminary results

Leticia Krauss-Silva, Maria Elizabeth L Moreira, Mariane B Alves, Alcione Braga, Karla G Camacho, Maria Rosa R Batista, Antonio Almada-Horta, Maria R Rebello, Fernando Guerra

A meta-review of evidence on heart failure disease management programs: the challenges of describing and synthesizing evidence on complex interventions

Lori A Savard, David R Thompson, Alexander M Clark

Illness management and recovery (IMR) in Danish community mental health centres

Helle Dalum, Lisa Korsbek, John Mikkelsen, Karin Thomsen, Kristen Kistrup, Mette Olander, Jane Hansen, Merete Nordentoft, Lene Eplov

The effect of family-based multidisciplinary cognitive behavioral treatment in children with obesity: study protocol for a randomized controlled trial

Rimke C Vos, Jan M Wit, Hanno Pijl, Carolien C Kruyff, Euphemia CAM Houdijk

Collaborative research between academia and industry using a large clinical trial database: a case study in Alzheimer's disease

Roy Jones, David Wilkinson, Oscar L Lopez, Jeffrey Cummings, Gunhild Waldemar, Richard Zhang, Joan Mackell, Serge Gauthier

Psycho-education with problem solving (PEPS) therapy for adults with personality disorder: A pragmatic multi-site community-based randomised clinical trial

Mary McMurran, Mike J Crawford, Joseph G Reilly, Paul McCrone, Paul Moran, Hywel Williams, Clive E Adams, Conor Duggan, Juan Delport, Diane Whitham, Florence Day

Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit

Patrick Royston, Friederike M-S Barthel, Mahesh KB Parmar, Babak Choodari-Oskooei, Valerie Isham

Vocational rehabilitation services for patients with cancer: design of a feasibility study incorporating a pilot randomised controlled trial among women with breast cancer following surgery

Richard G Kyle, Bill Culbard, Josie Evans, Nicola M Gray, Dolapo Ayansina, Gill Hubbard

Effect of a single dose of pregabalin on herpes zoster pain

Christina Jensen-Dahm, Michael C Rowbotham, Haatem Reda, Karin Petersen

Cognitive activity for the treatment of older adults with mild Alzheimer's Disease (AD) - PACE AD: study protocol for a randomised controlled trial

Mandy R Vidovich, Josephine Shaw, Leon Flicker, Osvaldo P Almeida

The incredible years therapeutic dinosaur programme to build social and emotional competence in welsh primary schools: study protocol for a randomised controlled trial

Tracey Bywater, Judy Hutchings, Christopher Whitaker, Ceri Evans, Laura Parry

Acupuncture for sequelae of Bell's palsy: a randomized controlled trial protocol

Hyo-Jung Kwon, Jong-In Kim, Myeong Lee, Jun-Yong Choi, Sungkeel Kang, Jie-Yoon Chung, Young-Jin Kim, Seung-Hoon Lee, Sanghoon Lee, Dongwoo Nam, Yong-Suk Kim, Jae-Dong Lee, Do-Young Choi

A factorial randomized controlled trial to evaluate the effect of micronutrients supplementation and regular aerobic exercise on maternal endothelium-dependent vasodilatation and oxidative stress of the newborn

Robinson Ramírez-Vélez, Miryam Romero, Isabella Echeverri, José Ortega, Mildrey Mosquera, Blanca Salazar, Sandra Girón, Wilmar Saldarriaga, Ana Aguilar de Plata, Julio Mateus

Single-dose liposomal amphotericin B (AmBisome？) for the treatment of Visceral Leishmaniasis in East Africa: study protocol for a randomized controlled trial

Tansy Edwards, Raymond Omollo, Eltahir AG Khalil, Sisay Yifru, Brima Musa, Ahmed Musa, Monique Wasunna, Peter G Smith, Catherine Royce, Sally Ellis, Manica Balasegaram, Asrat Hailu

Using a business model approach and marketing techniques for recruitment to clinical trials

Alison M McDonald, Shaun Treweek, Haleema Shakur, Caroline Free, Rosemary Knight, Chris Speed, Marion K Campbell

Efficacy of essential oil mouthwash with and without alcohol: a 3-Day plaque accumulation model

Enrico Marchetti, Stefano Mummolo, Jonathan Di Mattia, Fabio Casalena, Salvatore Di Martino, Antonella Mattei, Giuseppe Marzo

Randomized, double-blind, placebo-controled clinical trial of sublingual immunotherapy in natural rubber latex allergic patients

Gabriel Gastaminza, Jaime Algorta, Olga Uriel, Maria T Audicana, Eduardo Fernandez, Maria L Sanz, Daniel Mu？oz

Investigating a TELEmedicine solution to improve MEDication adherence in chronic Heart Failure (TELEMED-HF): study protocol for a randomized controlled trial

Dionne Kessing, Johan Denollet, Jos Widdershoven, Nina Kupper

A randomised evaluation of CollAborative care and active surveillance for Screen-Positive EldeRs with sub-threshold depression (CASPER): study protocol for a randomized controlled trial

Natasha Mitchell, Catherine Hewitt, Joy Adamson, Steve Parrott, David Torgerson, David Ekers, John Holmes, Helen Lester, Dean McMillan, David Richards, Karen Spilsbury, Christine Godfrey, Simon Gilbody

Comparisons against baseline within randomised groups are often used and can be highly misleading

J Martin Bland, Douglas G Altman

Investigating a training supporting shared decision making (IT'S SDM 2011): study protocol for a randomized controlled trial

Friedemann Geiger, Katrin Liethmann, Frauke Hoffmann, Jutta Paschedag, Jürgen Kasper

Comparison of early-, late-, and non-participants in a school-based asthma management program for urban high school students

Christine LM Joseph, Jacquelyn Saltzgaber, Suzanne L Havstad, Christine C Johnson, Dayna Johnson, Edward L Peterson, Gwen Alexander, Mick P Couper, Dennis R Ownby

Social validity of randomised controlled trials in health services research and intellectual disabilities: a qualitative exploration of stakeholder views

Dan Robotham, Michael King, Anton Canagasabey, Sophie Inchley-Mort, Angela Hassiotis

A randomised sham controlled trial of vertebroplasty for painful acute osteoporotic vertebral fractures (VERTOS IV)

Cristina Firanescu, Paul NM Lohle, Jolanda de Vries, Caroline A Klazen, Job R Juttmann, William Clark, Willem van Rooij, the VERTOS IV study group

Standard requirements for GCP-compliant data management in multinational clinical trials

Christian Ohmann, Wolfgang Kuchinke, Steve Canham, Jens Lauritsen, Nader Salas, Carmen Schade-Brittinger, Michael Wittenberg, Gladys McPherson, John McCourt, Francois Gueyffier, Andrea Lorimer, Ferràn Torres, the ECRIN Working Group on Data Centres

Assessment of the consistency and robustness of results from a multicenter trial of remission maintenance therapy for acute myeloid leukemia

Marc Buyse, Pierre Squifflet, Kathryn J Lucchesi, Mats L Brune, Sylvie Castaigne, Jacob M Rowe

Adverse events associated with acupuncture: three multicentre randomized controlled trials of 1968 cases in China

Ling Zhao, Fu-wen Zhang, Ying Li, Xi Wu, Hui Zheng, Lin-hao Cheng, Fan-rong Liang

Use of deferred consent for severely ill children in a multi-centre phase III trial

Kathryn Maitland, Sassy Molyneux, Mwamvua Boga, Sarah Kiguli, Trudie Lang

Effectiveness of technology-assisted case management in low income adults with type 2 diabetes (TACM-DM): study protocol for a randomized controlled trial

Leonard E Egede, Joni L Strom, Jyotika Fernandes, Rebecca G Knapp, Adebola Rojugbokan

Effectiveness of an online group course for adolescents and young adults with depressive symptoms: study protocol for a randomized controlled trial

Rianne AP van der Zanden, Jeannet JAM Kramer, Pim Cuijpers

Alzheimer's disease - input of vitamin D with mEmantine assay (AD-IDEA trial): study protocol for a randomized controlled trial

Cédric Annweiler, Bruno Fantino, Elsa Parot-Schinkel, Samuel Thiery, Jennifer Gautier, Olivier Beauchet

Which dressing do donor site wounds need?: study protocol for a randomized controlled trial

Anne M Eskes, Fleur E Br？lmann, Louise AA Gerbens, Dirk T Ubbink, Hester Vermeulen, The REMBRANDT study group (REMBRANDT)

Corticotherapy for traumatic brain-injured Patients - The Corti-TC trial: study protocol for a randomized controlled trial

Karim Asehnoune, Antoine Roquilly, Véronique Sebille, The Corti-TC trial group

A practice-based trial of blood pressure control in African Americans (TLC-Clinic): study protocol for a randomized controlled trial

Antoinette Schoenthaler, Leanne Luerassi, Jeanne A Teresi, Stephanie Silver, Jian Kong, Taiye Odedosu, Samantha Trilling, Anna Errico, Oshevire Uvwo, Kimberly Sebek, Adetutu Adekoya, Gbenga Ogedegbe

Oxygen persufflation as adjunct in liver preservation (OPAL): Study protocol for a randomized controlled trial

Thomas Minor, Carolin Pütter, Anja Gallinat, Claudia Ose, Gernot Kaiser, Andre Scherag, Jürgen Treckmann, Andreas Paul

Managing the environmental impact of research

David C Pencheon

Key issues in recruitment to randomised controlled trials with very different interventions: a qualitative investigation of recruitment to the SPARE trial (CRUK/07/011)

Sangeetha Paramasivan, Robert Huddart, Emma Hall, Rebecca Lewis, Alison Birtle, Jenny L Donovan

Exercise Training in Pregnancy for obese women (ETIP): study protocol for a randomised controlled trial

Trine T Moholdt, Kjell Salvesen, Charlotte B Ingul, Torstein Vik, Emily Oken, Siv M？rkved

Randomized placebo-controlled trial on azithromycin to reduce the morbidity of bronchiolitis in Indigenous Australian infants: rationale and protocol

Anne B Chang, Keith Grimwood, Andrew V White, Carolyn Maclennan, Theo P Sloots, Alan Sive, Gabrielle B McCallum, Ian M Mackay, Peter S Morris

Cognitive behaviour therapy (CBT) for anxiety and depression in adults with mild intellectual disabilities (ID): a pilot randomised controlled trial

Angela Hassiotis, Marc Serfaty, Kiran Azam, Andre Strydom, Sue Martin, Charles Parkes, Robert Blizard, Michael King

To assess whether indoor residual spraying can provide additional protection against clinical malaria over current best practice of long-lasting insecticidal mosquito nets in The Gambia: study protocol for a two-armed cluster-randomised trial

Margaret Pinder, Musa Jawara, Lamin BS Jarju, Ballah Kandeh, David Jeffries, Manuel F Lluberas, Jenny Mueller, David Parker, Kalifa Bojang, David J Conway, Steve W Lindsay

Evaluation of wet-cupping therapy for persistent non-specific low back pain: a randomised, waiting-list controlled, open-label, parallel-group pilot trial

Jong-In Kim, Tae-Hun Kim, Myeong Lee, Jung Kang, Kun Kim, Jun-Yong Choi, Kyung-Won Kang, Ae-Ran Kim, Mi-Suk Shin, So-Young Jung, Sun-mi Choi

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