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Trials

ISSN Print: 1745-6215

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Website: http://www.trialsjournal.com

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Evaluating the effectiveness of reasoning training in military and civilian chronic traumatic brain injury patients: study protocol

Krawczyk Daniel C,de la Plata Carlos Marquez,Schauer Guido F,Vas Asha K

Introduction to a generalized method for adaptive randomization in trials

Hoare Zo？ SJ,Whitaker Christopher J,Whitaker Rhiannon

Pulmonary perfusion with oxygenated blood or custodiol HTK solution during cardiac surgery for postoperative pulmonary function in COPD patients: a trial protocol for the randomized, clinical, parallel group, assessor and data analyst blinded Pulmonary Protection Trial

Buggeskov Katrine B,Wetterslev J？rn,Secher Niels H,Andersen Lars W

Collaborative Care for Older Adults with low back pain by family medicine physicians and doctors of chiropractic (COCOA): study protocol for a randomized controlled trial

Goertz Christine M,Salsbury Stacie A,Vining Robert D,Long Cynthia R

Sentinel node in ovarian cancer: study protocol for a phase 1 study

Kleppe Marjolein,Van Gorp Toon,Slangen Brigitte FM,Kruse Arnold J

Bee venom acupuncture for the treatment of chronic low back pain: study protocol for a randomized, double-blinded, sham-controlled trial

Seo Byung-Kwan,Lee Jun-Hwan,Sung Won-Suk,Song Eun-Mo

Bronchiectasis exacerbation study on azithromycin and amoxycillin-clavulanate for respiratory exacerbations in children (BEST-2): study protocol for a randomized controlled trial

Chang Anne B,Grimwood Keith,Wilson Andrew C,van Asperen Peter P

Researchers’ perceptions of ethical challenges in cluster randomized trials: a qualitative analysis

McRae Andrew D,Bennett Carol,Brown Judith Belle,Weijer Charles

Early treatment of posterior crossbite - a randomised clinical trial

Lippold Carsten,Stamm Thomas,Meyer Ulrich,Végh András

The group-based social skills training SOSTA-FRA in children and adolescents with high functioning autism spectrum disorder - study protocol of the randomised, multi-centre controlled SOSTA - net trial

Freitag Christine M,Cholemkery Hannah,Elsuni Leyla,Kroeger Anne K

Use of the PiCCO system in critically ill patients with septic shock and acute respiratory distress syndrome: a study protocol for a randomized controlled trial

Zhang Zhongheng,Xu Xiao,Yao Min,Chen Huilan

Effects of acupuncture treatment on depression insomnia: a study protocol of a multicenter randomized controlled trial

Chen Yuan-Fang,Liu Jian-Hua,Xu Neng-Gui,Liang Zhao-Hui

An oral preparation of Lactobacillus acidophilus for the treatment of uncomplicated acute watery diarrhoea in Vietnamese children: study protocol for a multicentre, randomised, placebo-controlled trial

Kolader Marion-Eli？tte,Vinh Ha,Ngoc Tuyet Pham Thi,Thompson Corinne

Optimal schedule of adjuvant chemotherapy with S-1 for stage III colon cancer: study protocol for a randomized controlled trial

Yoshimura Kenichi,Uehara Keisuke,Tojima Yuichiro,Kawai Satoru

Cellular versus acellular matrix devices in treatment of diabetic foot ulcers: study protocol for a comparative efficacy randomized controlled trial

Lev-Tov Hadar,Li Chin-Shang,Dahle Sara,Isseroff Roslyn Rivkah

Rotterdam Aphasia Therapy Study (RATS) – 3: “The efficacy of intensive cognitive-linguistic therapy in the acute stage of aphasia”; design of a randomised controlled trial

Nouwens Femke,Dippel Diederik WJ,de Jong-Hagelstein Marjolein,Visch-Brink Evy G

The impact of hotspot-targeted interventions on malaria transmission: study protocol for a cluster-randomized controlled trial

Bousema Teun,Stevenson Jennifer,Baidjoe Amrish,Stresman Gillian

A nurse- and peer-led support program to assist women in gynaecological oncology receiving curative radiotherapy, the PeNTAGOn study (Peer and nurse support trial to assist women in gynaecological oncology): study protocol for a randomised controlled trial

Schofield Penelope,Juraskova Ilona,Bergin Rebecca,Gough Karla

The Nordic Aortic Valve Intervention (NOTION) trial comparing transcatheter versus surgical valve implantation: study protocol for a randomised controlled trial

Thyregod Hans Gustav,S？ndergaard Lars,Ihlemann Nikolaj,Franzen Olaf

Practical health co-operation - the impact of a referral template on quality of care and health care co-operation: study protocol for a cluster randomized controlled trial

W？hlberg Henrik,Valle Per Christian,Malm Siri,Broderstad Ann Ragnhild

Long-term consistent use of a vaginal microbicide gel among HIV-1 sero-discordant couples in a phase III clinical trial (MDP 301) in rural south-west Uganda

Abaasa Andrew,Crook Angela,Gafos Mitzy,Anywaine Zacchaeus

Can a core outcome set improve the quality of systematic reviews? – a survey of the Co-ordinating Editors of Cochrane review groups

Kirkham Jamie J,Gargon Elizabeth,Clarke Mike,Williamson Paula R

The effects on depression of Internet-administered behavioural activation and physical exercise with treatment rationale and relapse prevention: study protocol for a randomised controlled trial

Carlbring Per,Lindner Philip,Martell Christopher,Hassmén Peter

Effect of intermediate care on mortality following emergency abdominal surgery. The InCare trial: study protocol, rationale and feasibility of a randomised multicentre trial

Vester-Andersen Morten,Waldau Tina,Wetterslev J？rn,M？ller Morten Hylander

Use of the ‘patient journey’ model in the internet-based pre-fitting counseling of a person with hearing disability: study protocol for a randomized controlled trial

Manchaiah Vinaya KC,Stephens Dafydd,Andersson Gerhard,R？nnberg Jerker

Efficacy and mode of action of mesalazine in the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D): study protocol for a randomised controlled trial

Leighton Matthew P,Lam Ching,Mehta Samir,Spiller Robin C

Improving the application of a practice guideline for the assessment and treatment of suicidal behavior by training the full staff of psychiatric departments via an e-learning supported Train-the-Trainer program: study protocol for a randomized controlled trial

de Beurs Derek P,de Groot Marieke H,de Keijser Jos,Verwey Bastiaan

Blood pressure control and treatment adherence in hypertensive patients with metabolic syndrome: protocol of a randomized controlled study based on home blood pressure telemonitoring vs. conventional management and assessment of psychological determinants of adherence (TELEBPMET Study)

Parati Gianfranco,Omboni Stefano,Compare Angelo,Grossi Enzo

The NAILED stroke risk factor trial (Nurse based Age independent Intervention to Limit Evolution of Disease after stroke): study protocol for a randomized controlled trial

Mooe Thomas,Bergstr？m Lisa,Irewall Anna-Lotta,？gren Joachim

Acute cholecystitis in high risk surgical patients: percutaneous cholecystostomy versus laparoscopic cholecystectomy (CHOCOLATE trial): Study protocol for a randomized controlled trial

Kirsten Kortram, Bert van Ramshorst, Thomas L Bollen, Marc GH Besselink, Dirk J Gouma, Tom Karsten, Philip M Kruyt, Grard AP Nieuwenhuijzen, Johannes C Kelder, Ellen Tromp, Djamila Boerma

Efficacy of two educational interventions about inhalation techniques in patients with chronic obstructive pulmonary disease (COPD). TECEPOC: study protocol for a partially randomized controlled trial (preference trial)

Francisca Leiva-Fernández, José Leiva-Fernández, Fernando Zubeldia-Santoyo, Antonio García-Ruiz, Daniel Prados-Torres, Pilar Barnestein-Fonseca

Standard abdominal wound edge protection with surgical dressings vs coverage with a sterile circular polyethylene drape for prevention of surgical site infections (BaFO): study protocol for a randomized controlled trial

Andre L Mihaljevic, Christoph W Michalski, Mert Erkan, Carolin Reiser-Erkan, Carsten Jaeger, Tibor Schuster, Christoph Schuhmacher, J？rg Kleeff, Helmut Friess

Effect of traditional Chinese medicine on outcomes in patients with mild/moderate chronic obstructive pulmonary disease: study protocol for a randomized placebo-controlled trial

Wang Minghang, Li Jiansheng, Li Suyun, Wang Haifeng, Yu Xueqing, Zhang Hailong

Involvement of consumers in studies run by the Medical Research Council Clinical Trials Unit: Results of a survey

Claire L Vale, Lindsay C Thompson, Claire Murphy, Silvia Forcat, Bec Hanley

Motivational Interviewing with computer assistance as an intervention to empower women to make contraceptive choices while incarcerated: study protocol for randomized controlled trial

Jennifer G Clarke, Melanie A Gold, Rachel E Simon, L A.R. Stein

The effects of exercise during pregnancy on the newborn’s brain: study protocol for a randomized controlled trial

Elise L LeMoyne, Daniel Curnier, Samuel St-Jacques, Dave Ellemberg

Reducing inappropriate, anticholinergic and psychotropic drugs among older residents in assisted living facilities: study protocol for a randomized controlled trial

Kaisu H Pitkala, Anna-Liisa Juola, Helena Soini, Marja-Liisa Laakkonen, Hannu Kautiainen, Mariko Teramura-Gronblad, Harriet Finne-Soveri, Mikko Bjorkman

Stimulation of the autonomic nervous system in colorectal surgery: a study protocol for a randomized controlled trial

Tim M.P. Berghmans, Karel W.E. Hulsewé, Wim A. Buurman, Misha D.P. Luyer

Design and current status of CONTINT: continuous versus interrupted abdominal wall closure after emergency midline laparotomy - a randomized controlled multicenter trial [NCT00544583]

Nuh N Rahbari, Phillip Knebel, Meinhard Kieser, Thomas Bruckner, Detlef K Bartsch, Helmut Friess, Andre L Mihaljevic, Josef Stern, Markus K Diener, Sabine Voss, Inga Rossion, Markus W Buechler, Christoph M Seiler

An embedded longitudinal multi-faceted qualitative evaluation of a complex cluster randomized controlled trial aiming to reduce clinically important errors in medicines management in general practice

Kathrin M Cresswell, Stacey Sadler, Sarah Rodgers, Anthony Avery, Judith Cantrill, Scott A Murray, Aziz Sheikh

Nonadherence to treatment protocol in published randomised controlled trials: a review

Susanna R Dodd, Ian R White, Paula R Williamson

Effect of sequential treatment with syndrome differentiation on acute exacerbation of chronic obstructive pulmonary disease and "AECOPD Risk-Window": study protocol for a randomized placebo-controlled trial

Wang Haifeng, Li Jiansheng, Li Suyun, Yu Xueqing, Zhang Hailong, Wang Zhiwan, Wu Qiyi, Zhang Pankui, Wang Zhongchao, Li Fenglei, Yan Haihong

Effects of a manualized short-term treatment of internet and computer game addiction (STICA): study protocol for a randomized controlled trial

Susanne Jager, Kai W Muller, Christian Ruckes, Tobias Wittig, Anil Batra, Michael Musalek, Karl Mann, Klaus Wolfling, Manfred E Beutel

Pancreatogastrostomy versus pancreatojejunostomy for RECOnstruction after partial PANCreatoduodenectomy (RECOPANC): study protocol of a randomized controlled trial UTN U1111-1117-9588

Ulrich F Wellner, Sabine Brett, Thomas Bruckner, Ronald Limprecht, Inga Rossion, Christoph Seiler, Olivia Sick, Inga Wegener, Ulrich T Hopt, Tobias Keck

Use acupuncture to treat functional constipation: study protocol for a randomized controlled trial

Ying Li, Hui Zheng, Fang Zeng, Si-yuan Zhou, Feng Zhong, Hua-bing Zheng, Min Chen, Xiang-hong Jing, Yu-ying Cai, Bao-hui Jia, Bing Zhu, Zhi-shun Liu

Cognitive behavioural therapy versus multidisciplinary rehabilitation treatment for patients with chronic fatigue syndrome: study protocol for a randomised controlled trial (FatiGo)

Desirée CWM Vos-Vromans, Rob JEM Smeets, Leonie JM Rijnders, René RM Gorrissen, Menno Pont, Albère JA K？ke, Minou WMGC Hitters, Silvia MAA Evers, André J Knottnerus

Self-help materials for the prevention of smoking relapse: study protocol for a randomized controlled trial

Fujian Song, Richard Holland, Garry R Barton, Max Bachmann, Annie Blyth, Viv Maskrey, Paul Aveyard, Stephen Sutton, Jo Leonardi-Bee, Thomas H Brandon

Inadequate description of educational interventions in ongoing randomized controlled trials

Cécile Pino, Isabelle Boutron, Philippe Ravaud

Assessing the effectiveness of ‘pulse radiofrequency treatment of dorsal root ganglion’ in patients with chronic lumbar radicular pain: study protocol for a randomized control trial

Harsha Shanthanna, Philip Chan, James McChesney, James Paul, Lehana Thabane

Aerobic endurance training versus relaxation training in patients with migraine (ARMIG): study protocol for a randomized controlled trial

Andreas Totzeck, Susanne Unverzagt, Maja Bak, Pierre Augst, Hans C Diener, Charly Gaul

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