Genome Medicine - oalib

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Genome Medicine

ISSN Print: 1756-994X

ISSN Online:

主页: http://genomemedicine.com

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Sex chromosomes and genetic association studies

David G Clayton

Bridging the gap between systems biology and medicine

Gilles Clermont, Charles Auffray, Yves Moreau, David M Rocke, Daniel Dalevi, Devdatt Dubhashi, Dana R Marshall, Peter Raasch, Frank Dehne, Paolo Provero, Jesper Tegner, Bruce J Aronow, Michael A Langston, Mikael Benson

Musings on genome medicine: Crohn's disease

David G Nathan, Stuart H Orkin

Data reporting standards: making the things we use better

John Quackenbush

Tackling the methylome: recent methodological advances in genome-wide methylation profiling

Marcos RH Estécio, Jean-Pierre J Issa

A role for neurotransmission and neurodevelopment in attention-deficit/hyperactivity disorder

Tatiana Roman, Luis A Rohde, Mara H Hutz

Secretome: clues into pathogen infection and clinical applications

Shoba Ranganathan, Gagan Garg

Insights from Keystone: advances in the understanding of epigenetic regulation of the genome

Rebecca C Rancourt, Nico Ruf

Commercialization, patenting and genomics: researcher perspectives

CJ Murdoch, Timothy Caulfield

The Human Gene Mutation Database: 2008 update

Peter D Stenson, Matthew Mort, Edward V Ball, Katy Howells, Andrew D Phillips, Nick ST Thomas, David N Cooper

Genome Medicine: the future of medicine

Melissa L Norton

A kernel-based integration of genome-wide data for clinical decision support

Anneleen Daemen, Olivier Gevaert, Fabian Ojeda, Annelies Debucquoy, Johan AK Suykens, Christine Sempoux, Jean-Pascal Machiels, Karin Haustermans, Bart De Moor

Two cheers for GINA?

Amy L McGuire, Mary Majumder

Genomic disorders ten years on

James R Lupski

Dissecting complex traits: recent advances in hypertension genomics

Kevin M O'Shaughnessy

Gene-gene and gene-environment interactions: new insights into the prevention, detection and management of coronary artery disease

Matthew B Lanktree, Robert A Hegele

Copy number variation and genomic alterations in health and disease

George P Patrinos, Michael B Petersen

Musings on genome medicine: gene therapy

David G Nathan, Stuart H Orkin

Genome-based prediction of common diseases: methodological considerations for future research

A Cecile JW Janssens, Cornelia M van Duijn

A new, effective and high-yield approach for identifying liver tumor suppressors

Esra Olgun, Lewis R Roberts

Musings on genome medicine: abuse of genetic tests

David G Nathan, Stuart H Orkin

Huntington's disease: the case for genetic modifiers

James F Gusella, Marcy E MacDonald

Does genomic risk information motivate people to change their behavior?

Nora B Henrikson, Deborah Bowen, Wylie Burke

Genetics of Alzheimer's disease: recent advances

Dimitrios Avramopoulos

Applications of metabolomics and proteomics to the mdx mouse model of Duchenne muscular dystrophy: lessons from downstream of the transcriptome

Julian L Griffin, Christine Des Rosiers

Pharmacogenomics of anticoagulants: steps toward personal dosage

Ann K Daly

Ancestry in translational genomic medicine: handle with care

David Gurwitz, Jeantine E Lunshof

A small step closer to the Holy Grail of DNA vaccines: undisputed clinical benefit in humans

Lars Frelin, Matti S？llberg

The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy

Nadine Van Roy, Katleen De Preter, Jasmien Hoebeeck, Tom Van Maerken, Filip Pattyn, Pieter Mestdagh, Jo？lle Vermeulen, Jo Vandesompele, Frank Speleman

Perspectives in stem cell proteomics

Javier Mu？oz, Albert JR Heck

New strategies and emerging technologies for massively parallel sequencing: applications in medical research

Elaine R Mardis

Genome-wide association studies in pharmacogenomics: untapped potential for translation

Idris Guessous, Marta Gwinn, Muin J Khoury

Overexpression of MACC1 leads to downstream activation of HGF/MET and potentiates metastasis and recurrence of colorectal cancer

Lisa A Boardman

Musings on genome medicine: is there hope for ethical and safe stem cell therapeutics?

Mahendra Rao, Maureen L Condic

Linking genes to diseases: it's all in the data

Nicki Tiffin, Miguel A Andrade-Navarro, Carolina Perez-Iratxeta

Genomic electronic health records: opportunities and challenges

Mohammad Al-Ubaydli, Rob Navarro

Lithium: a key to the genetics of bipolar disorder

Cristiana Cruceanu, Martin Alda, Gustavo Turecki

Musings on genome medicine: the slow but inexorable process of medical care reform in the United States

David G Nathan, Stuart H Orkin

From association to causality: the new frontier for complex traits

Nicholas Katsanis

Direct-to-consumer genetic tests: beyond medical regulation?

David Magnus, Mildred K Cho, Robert Cook-Deegan

Germline and somatic JAK2 mutations and susceptibility to chronic myeloproliferative neoplasms

Lynn R Goldin, Magnus Bj？rkholm, Sigurdur Y Kristinsson, Jan Samuelsson, Ola Landgren

The cycle of genome-directed medicine

Janet A Buchanan, Andrew R Carson, David Chitayat, David Malkin, M Stephen Meyn, Peter N Ray, Cheryl Shuman, Rosanna Weksberg, Stephen W Scherer

Novel insights into proteomic technologies and their clinical perspective

Gunnar Dittmar, Matthias Selbach

Genomic medicine: considerations for health professionals and the public

Denise Avard, Bartha Knoppers

Chipping away at the common epilepsies with complex genetics: the 15q13.3 microdeletion shows the way

John C Mulley, Leanne M Dibbens

Insights into gliomagenesis: systems biology unravels key pathways

Sandro J de Souza, Beatriz Stransky, Anamaria A Camargo

Rheumatoid arthritis: GWAS or TMI?

Bruce N Cronstein

Translating genomics into the clinic: moving to the post-Mendelian world

Mildred K Cho

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