Molecular Cancer - oalib

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ISSN: 2333-9721
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Molecular Cancer

ISSN Print: 1476-4598

ISSN Online:

主页: http://www.molecular-cancer.com

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The Involvement of Bax in Zinc-Induced Mitochondrial Apoptogenesis in Malignant Prostate Cells

Pei Feng, Tieluo Li, Zhixin Guan, Renty B Franklin, Leslie C Costello

Transduction of E2F-1 TAT fusion proteins represses expression of hTERT in primary ductal breast carcinoma cell lines

Kimberly A Elliott, Lee F Rickords, J Marcelete Labrum

Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cγ at the centrosome

Hélène Lelièvre, Véronique Chevrier, Anne-Marie Tassin, Daniel Birnbaum

Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning 1H magnetic resonance spectroscopy

Therese Seierstad, Kathrine R？e, Beathe Sitter, Jostein Halgunset, Kjersti Flatmark, Anne H Ree, Dag Olsen, Ingrid S Gribbestad, Tone F Bathen

Transcription analysis in the MeLiM swine model identifies RACK1 as a potential marker of malignancy for human melanocytic proliferation

Giorgia Egidy, Sophia Julé, Philippe Bossé, Florence Bernex, Claudine Geffrotin, Silvia Vincent-Naulleau, Vratislav Horak, Xavier Sastre-Garau, Jean-Jacques Panthier

DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk

Dominique Bernard-Gallon, Rémy Bosviel, Laetitia Delort, Luc Fontana, Alain Chamoux, Nadège Rabiau, Fabrice Kwiatkowski, Nasséra Chalabi, Samir Satih, Yves-Jean Bignon

Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain

Purna Mukherjee, Tiernan J Mulrooney, Jeremy Marsh, Derek Blair, Thomas C Chiles, Thomas N Seyfried

Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells

Tamer E Fandy, Sharmila Shankar, Rakesh K Srivastava

Evidence for efficient phosphorylation of EGFR and rapid endocytosis of phosphorylated EGFR via the early/late endocytic pathway in a gefitinib-sensitive non-small cell lung cancer cell line

Yukio Nishimura, Kiyoko Yoshioka, Biborka Bereczky, Kazuyuki Itoh

The LIM and SH3 domain protein family: structural proteins or signal transducers or both?

Thomas GP Grunewald, Elke Butt

Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers

Terje Ahlquist, Guro E Lind, Vera L Costa, Gunn I Meling, Morten Vatn, Geir S Hoff, Torleiv O Rognum, Rolf I Skotheim, Espen Thiis-Evensen, Ragnhild A Lothe

Reduction of human chorionic gonadotropin beta subunit expression by modified U1 snRNA caused apoptosis in cervical cancer cells

Anna Jankowska, Samuel I Gunderson, Miroslaw Andrusiewicz, Beata Burczynska, Anna Szczerba, Artur Jarmolowski, Ewa Nowak-Markwitz, Jerzy B Warchol

Correlation between β-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma

Madeleine Austinat, Ruediger Dunsch, Christian Wittekind, Andrea Tannapfel, Rolf Gebhardt, Frank Gaunitz

Complex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells

Annick Mühlethaler-Mottet, Roland Meier, Marjorie Flahaut, Katia Bourloud, Katya Nardou, Jean-Marc Joseph, Nicole Gross

Stabilizing mutation of CTNNB1/beta-catenin and protein accumulation analyzed in a large series of parathyroid tumors of Swedish patients

Peyman Bj？rklund, Daniel Lindberg, G？ran ？kerstr？m, Gunnar Westin

Meta-analysis of human cancer microarrays reveals GATA3 is integral to the estrogen receptor alpha pathway

Brian J Wilson, Vincent Giguère

Altered splicing of CEACAM1 in breast cancer: Identification of regulatory sequences that control splicing of CEACAM1 into long or short cytoplasmic domain isoforms

Shikha Gaur, John E Shively, Yun Yen, Rajesh K Gaur

Transformation of MCF-10A cells by random mutagenesis with frameshift mutagen ICR191: A model for identifying candidate breast-tumor suppressors

Helena Zientek-Targosz, Dimiter Kunnev, Lesleyann Hawthorn, Mikhail Venkov, Sei-Ichi Matsui, Richard T Cheney, Yuri Ionov

Effect of bortezomib on human neuroblastoma: analysis of molecular mechanisms involved in cytotoxicity

Valérie Combaret, Sandrine Boyault, Isabelle Iacono, Stéphanie Brejon, Rapha？l Rousseau, Alain Puisieux

Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma

David T Yang, Ken H Young, Brad S Kahl, Stephanie Markovina, Shigeki Miyamoto

Evaluation of cell types for assessment of cytogenetic damage in arsenic exposed population

Pritha Ghosh, Arindam Basu, Keshav K Singh, Ashok K Giri

ret/PTC-1 expression alters the immunoprofile of thyroid follicular cells

Karen Denning, Paul Smyth, Susanne Cahill, Jinghuan Li, Richard Flavin, Sinead Aherne, John J O' Leary, Orla Sheils

Eplin-alpha expression in human breast cancer, the impact on cellular migration and clinical outcome

Wen G Jiang, Tracey A Martin, Jonathan M Lewis-Russell, Anthony Douglas-Jones, Lin Ye, Robert E Mansel

Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK

Klaus Dittmann, Claus Mayer, Rainer Kehlbach, H Peter Rodemann

Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha

Luigi Scotto, Gopeshwar Narayan, Subhadra V Nandula, Shivakumar Subramaniyam, Andreas M Kaufmann, Jason D Wright, Bhavana Pothuri, Mahesh Mansukhani, Achim Schneider, Hugo Arias-Pulido, Vundavalli V Murty

The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3

Sunita K Agarwal, William F Simonds, Stephen J Marx

Soluble histone H2AX is induced by DNA replication stress and sensitizes cells to undergo apoptosis

Ying Liu, Joshua A Parry, Anna Chin, Stefan Duensing, Anette Duensing

Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells

Marielle Dejligbjerg, Morten Grauslund, Thomas Litman, Laura Collins, Xiaozhong Qian, Michael Jeffers, Henri Lichenstein, Peter Jensen, Maxwell Sehested

Identification of metabolites with anticancer properties by computational metabolomics

Adrian K Arakaki, Roman Mezencev, Nathan J Bowen, Ying Huang, John F McDonald, Jeffrey Skolnick

Sub-megabase resolution tiling (SMRT) array-based comparative genomic hybridization profiling reveals novel gains and losses of chromosomal regions in Hodgkin Lymphoma and Anaplastic Large Cell Lymphoma cell lines

Faisal M Fadlelmola, Minglong Zhou, Ronald J de Leeuw, Nirpjit S Dosanjh, Karynn Harmer, David Huntsman, Wan L Lam, Diponkar Banerjee

Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma

Eric Smith, Neville J De Young, Sandra J Pavey, Nicholas K Hayward, Derek J Nancarrow, David C Whiteman, B Mark Smithers, Andrew R Ruszkiewicz, Andrew D Clouston, David C Gotley, Peter G Devitt, Glyn G Jamieson, Paul A Drew

A conserved acidic patch in the Myb domain is required for activation of an endogenous target gene and for chromatin binding

Emily Ko, Dennis Ko, Carolyn Chen, Joseph S Lipsick

Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells

Pinella Buongiorno, Vaijayanti V Pethe, George S Charames, Susmita Esufali, Bharati Bapat

Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes

Teresa WM Fan, Magda Kucia, Kacper Jankowski, Richard M Higashi, Janina Ratajczak, Marius Z Ratajczak, Andrew N Lane

Down-regulation of PPARgamma1 suppresses cell growth and induces apoptosis in MCF-7 breast cancer cells

Yekaterina Y Zaytseva, Xin Wang, R Chase Southard, Natalie K Wallis, Michael W Kilgore

The problem of choice

Hassan R Naqvi, Shawn Mathur, David Covarrubias, Josephine A Curcio, Christian Schmidt

Membrane androgen receptor activation triggers down-regulation of PI-3K/Akt/NF-kappaB activity and induces apoptotic responses via Bad, FasL and caspase-3 in DU145 prostate cancer cells

Natalia Papadopoulou, Ioannis Charalampopoulos, Vasileia Anagnostopoulou, Georgios Konstantinidis, Michael F？ller, Achilleas Gravanis, Konstantinos Alevizopoulos, Florian Lang, Christos Stournaras

Down-regulation of transforming growth factor-β type II receptor (TGF-βRII) protein and mRNA expression in cervical cancer

Jose Diaz-Chavez, Rogelio Hernandez-Pando, Paul F Lambert, Patricio Gariglio

Differential expression of metallothioneins (MTs) 1, 2, and 3 in response to zinc treatment in human prostate normal and malignant cells and tissues

Hua Wei, Mohamed Desouki, Shufei Lin, Dakai Xiao, Renty B Franklin, Pei Feng

Epigenetic changes within the promoter region of the HLA-G gene in ovarian tumors

Laura Menendez, L DeEtte Walker, Lilya V Matyunina, Kimberly A Totten, Benedict B Benigno, John F McDonald

Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile

Fran？ois Ducray, Ahmed Idbaih, Aurélien de Reyniès, Ivan Bièche, Jo？lle Thillet, Karima Mokhtari, Séverine Lair, Yannick Marie, Sophie Paris, Michel Vidaud, Khê Hoang-Xuan, Olivier Delattre, Jean-Yves Delattre, Marc Sanson

COX-2 inhibition is neither necessary nor sufficient for celecoxib to suppress tumor cell proliferation and focus formation in vitro

Huan-Ching Chuang, Adel Kardosh, Kevin J Gaffney, Nicos A Petasis, Axel H Sch？nthal

Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1

Mollie H Wright, Ana I Robles, Jason I Herschkowitz, Melinda G Hollingshead, Miriam R Anver, Charles M Perou, Lyuba Varticovski

Potential role of miR-9 and miR-223 in recurrent ovarian cancer

Alexandros Laios, Sharon O'Toole, Richard Flavin, Cara Martin, Lynne Kelly, Martina Ring, Stephen P Finn, Ciara Barrett, Massimo Loda, Noreen Gleeson, Tom D'Arcy, Eamonn McGuinness, Orla Sheils, Brian Sheppard, John O' Leary

DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein

Jing An, Dong-Yan Yang, Qin-Zhi Xu, Shi-Meng Zhang, Yan-Ying Huo, Zeng-Fu Shang, Yu Wang, De-Chang Wu, Ping-Kun Zhou

Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model

Alan A Arnold, Amro Aboukameel, Jianyong Chen, Dajun Yang, Shaomeng Wang, Ayad Al-Katib, Ramzi M Mohammad

In Silico analysis of Gastric carcinoma Serial Analysis of Gene Expression libraries reveals different profiles associated with ethnicity

Francisco J Ossandon, Cynthia Villarroel, Francisco Aguayo, Eudocia Santibanez, Naohide Oue, Wataru Yasui, Alejandro H Corvalan

Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer

Paul P Anglim, Janice S Galler, Michael N Koss, Jeffrey A Hagen, Sally Turla, Mihaela Campan, Daniel J Weisenberger, Peter W Laird, Kimberly D Siegmund, Ite A Laird-Offringa

Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression

Zhong Wang, Philip S Lecane, Patricia Thiemann, Qing Fan, Cecilia Cortez, Xuan Ma, Danielle Tonev, Dale Miles, Louie Naumovski, Richard A Miller, Darren Magda, Dong-Gyu Cho, Jonathan L Sessler, Brian L Pike, Samantha M Yeligar, Mazen W Karaman, Joseph G Hacia

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