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Molecular Cancer

ISSN Print: 1476-4598

ISSN Online:

Website: http://www.molecular-cancer.com

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Quantitation of cell-free DNA and RNA in plasma during tumor progression in rats

García-Olmo Dolores C,Picazo María G,Toboso Inmaculada,Asensio Ana I

Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells

Smith Charlotte M,Haucke Volker,McCluskey Adam,Robinson Phillip J

Thanking our peer reviewers

Storey Alan

The Wilms’ tumor gene (WT1) regulates E-cadherin expression and migration of prostate cancer cells

Brett Adina,Pandey Sony,Fraizer Gail

Head and neck cancer cells and xenografts are very sensitive to palytoxin: decrease of c-jun n-terminale kinase-3 expression enhances palytoxin toxicity

G？r？gh Tibor,Bèress László,Quabius Elgar S,Ambrosch Petra

Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion

Sengupta Neel,Yau Christopher,Sakthianandeswaren Anuratha,Mouradov Dmitri

Combining phenotypic and proteomic approaches to identify membrane targets in a ‘triple negative’ breast cancer cell type

Rust Steven,Guillard Sandrine,Sachsenmeier Kris,Hay Carl

Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer

Li Yuanyuan,Meeran Syed M,Patel Shweta N,Chen Huaping

POU1F1 is a novel fusion partner of NUP98 in acute myeloid leukemia with t(3;11)(p11;p15)

Lisboa Susana,Cerveira Nuno,Bizarro Susana,Correia Cecília

The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma

Anna Djos, Tommy Martinsson, Per Kogner, Helena Caren

Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells

Elisa Latorre, Toma Tebaldi, Gabriella Viero, Antonino Spartà, Alessandro Quattrone, Alessandro Provenzani

IRF5 promotes the proliferation of human thyroid cancer cells

Michele Massimino, Paolo Vigneri, Manuela Fallica, Annamaria Fidilio, Alessandra Aloisi, Francesco Frasca, Livia Manzella

MicroRNA-143 Targets MACC1 to Inhibit Cell Invasion and Migration in Colorectal cancer

Yu Zhang, Zhongqiu Wang, Min Chen, Liang Peng, Xinying Wang, Qunying Ma, Fengli Ma, Bo Jiang

Inhibition of HSP27 alone or in combination with pAKT inhibition as therapeutic approaches to target SPARC-induced glioma cell survival

Chad R Schultz, William A Golembieski, Daniel A King, Stephen L Brown, Chaya Brodie, Sandra A Rempel

c-Myb regulates matrix metalloproteinases 1/9, and cathepsin D: implications for matrix-dependent breast cancer cell invasion and metastasis

Lucia Knopfová, Petr Bene？, Lucie Pekar？íková, Markéta Hermanová, Michal Masa？ík, Zuzana Pernicová, Karel Sou？ek, Jan ？marda

Wnt signaling pathways in urological cancers: past decades and still growing

Shahana Majid, Sharanjot Saini, Rajvir Dahiya

Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1

Louise van der Weyden, Mark J Arends, Alistair G Rust, George Poulogiannis, Rebecca E McIntyre, David J Adams

The isoflavone metabolite 6-methoxyequol inhibits angiogenesis and suppresses tumor growth

Sofia Bellou, Evdoxia Karali, Eleni Bagli, Nawaf Al-Maharik, Lucia Morbidelli, Marina Ziche, Herman Adlercreutz, Carol Murphy, Theodore Fotsis

Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell lines

Erika von Euw, Mohammad Atefi, Narsis Attar, Connie Chu, Sybil Zachariah, Barry L Burgess, Stephen Mok, Charles Ng, Deborah J L Wong, Bartosz Chmielowski, David I Lichter, Richard C Koya, Tara A McCannel, Elena Izmailova, Antoni Ribas

Klotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth factor receptor-4 signaling in hepatocellular carcinoma

Weijie Poh, Winnie Wong, Huimin Ong, Myat Aung, Seng Lim, Boon Chua, Han Ho

Loss of HLTF function promotes intestinal carcinogenesis

Sumit Sandhu, Xiaoli Wu, Zinnatun Nabi, Mojgan Rastegar, Sam Kung, Sabine Mai, Hao Ding

Triplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer

Laura D Nelson, Christian Bender, Heiko Mannsperger, Daniel Buergy, Patryk Kambakamba, Giridhar Mudduluru, Ulrike Korf, Dennis Hughes, Michael W Van Dyke, Heike Allgayer

Role of toll-like receptor 4 on the immune escape of human oral squamous cell carcinoma and resistance of cisplatin-induced apoptosis

Zujun Sun, Qingqiong Luo, Dongxia Ye, Wantao Chen, Fuxiang Chen

Galectin-1, a gene preferentially expressed at the tumor margin, promotes glioblastoma cell invasion

L Gerard Toussaint III, Allan E Nilson, Jennie M Goble, Karla V Ballman, C David James, Florence Lefranc, Robert Kiss, Joon H Uhm

？3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells

David A Tumbarello, Jillian Temple, James D Brenton

Identification of cyclin B1 and Sec62 as biomarkers for recurrence in patients with HBV-related hepatocellular carcinoma after surgical resection

Li Weng, Juan Du, Qinghui Zhou, Binbin Cheng, Jun Li, Denghai Zhang, Changquan Ling

Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 receptor

Liron Zehavi, Roi Avraham, Aviv Barzilai, Dalia Bar-Ilan, Roy Navon, Yechezkel Sidi, Dror Avni, Raya Leibowitz-Amit

RhoA: A therapeutic target for chronic myeloid leukemia

Poonam R Molli, Madhura B Pradhan, Suresh H Advani, Nishigandha R Naik

MutS homologue hMSH5: role in cisplatin-induced DNA damage response

Joshua D Tompkins, Xiling Wu, Chengtao Her

Altered CXCR3 isoform expression regulates prostate cancer cell migration and invasion

Qian Wu, Rajiv Dhir, Alan Wells

Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells

Amanda B Hummon, Jason J Pitt, Jordi Camps, Georg Emons, Susan B Skube, Konrad Huppi, Tamara L Jones, Tim Beissbarth, Frank Kramer, Marian Grade, Michael J Difilippantonio, Thomas Ried, Natasha J Caplen

Syndecan-2 promotes perineural invasion and cooperates with K-ras to induce an invasive pancreatic cancer cell phenotype

Tiago De Oliveira, Ivane Abiatari, Susanne Raulefs, Danguole Sauliunaite, Mert Erkan, Bo Kong, Helmut Friess, Christoph W Michalski, J？rg Kleeff

Osteoblast-secreted collagen upregulates paracrine Sonic hedgehog signaling by prostate cancer cells and enhances osteoblast differentiation

Samantha M Zunich, Maria Valdovinos, Taneka Douglas, David Walterhouse, Philip Iannaccone, Marilyn LG Lamm

Temporally distinct roles for tumor suppressor pathways in cell cycle arrest and cellular senescence in Cyclin D1-driven tumor

Hasan Zalzali, Mohammad Harajly, Lina Abdul-Latif, Nader El Chaar, Ghassan Dbaibo, Stephen X Skapek, Raya Saab

Molecular mechanism implicated in Pemetrexed-induced apoptosis in human melanoma cells

Aitziber Buqué, Jangi Sh Muhialdin, Alberto Mu？oz, Bego？a Calvo, Sergio Carrera, Unai Aresti, Aintzane Sancho, Itziar Rubio, Guillermo López-Vivanco

miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated acute myeloid leukaemia and its suppression induces cell death

Adam Bryant, Catalina A Palma, Vivek Jayaswal, Yee Yang, Mark Lutherborrow, David DF Ma

Enhancement of lung tumorigenesis in a Gprc5a Knockout mouse by chronic extrinsic airway inflammation

Peter Barta, Carolyn Van Pelt, Taoyan Men, Burton F Dickey, Reuben Lotan, Seyed Javad Moghaddam

Estrogen receptor alpha deletion enhances the metastatic phenotype of Ron overexpressing mammary tumors in mice

Aaron M Marshall, Rebecca J McClaine, Devikala Gurusamy, Jerilyn K Gray, Kara E Lewnard, Sohaib A Khan, Susan E Waltz

miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer

Katarzyna Augoff, Brian McCue, Edward F Plow, Khalid Sossey-Alaoui

A STAT3-inhibitory hairpin decoy oligodeoxynucleotide discriminates between STAT1 and STAT3 and induces death in a human colon carcinoma cell line

Inès Souissi, Patrick Ladam, Jean AH Cognet, Stéphanie Le Coquil, Nadine Varin-Blank, Fanny Baran-Marszak, Valeri Metelev, Remi Fagard

Effect of cancer-associated mutations in the PlexinB1 gene

Chun Zhou, Oscar Wong, John R Masters, Magali Williamson

IGFBP3 impedes aggressive growth of pediatric liver cancer and is epigenetically silenced in vascular invasive and metastatic tumors

Ivonne Regel, Melanie Eichenmüller, Saskia Joppien, Johanna Liebl, Beate H？berle, Josef Müller-H？cker, Angelika Vollmar, Dietrich von Schweinitz, Roland Kappler

Nicotine, IFN-γ and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and utilize different signaling cascades

Sateesh Kunigal, Moorthy P Ponnusamy, Navneet Momi, Surinder K Batra, Srikumar P Chellappan

Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits

Ritu Jaiswal, Frederick Luk, Joyce Gong, Jean-Marie Mathys, Georges Emile Raymond Grau, Mary Bebawy

Lyn is involved in CD24-induced ERK1/2 activation in colorectal cancer

Ning Su, Liang Peng, Bingqing Xia, Yingying Zhao, Angao Xu, Jing Wang, Xinying Wang, Bo Jiang

Protective effect of the poly(ADP-ribose) polymerase inhibitor PJ34 on mitochondrial depolarization-mediated cell death in hepatocellular carcinoma cells involves attenuation of c-Jun N-terminal kinase-2 and protein kinase B/Akt activation

Balazs Radnai, Csenge Antus, Boglarka Racz, Peter Engelmann, Janos K Priber, Zsuzsanna Tucsek, Balazs Veres, Zsuzsanna Turi, Tamas Lorand, Balazs Sumegi, Ferenc Gallyas

Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines

Fiona O'Neill, Stephen F Madden, Sinead T Aherne, Martin Clynes, John Crown, Padraig Doolan, Robert O'Connor

Cisplatin and ultra-violet-C synergistically down-regulate receptor tyrosine kinases in human colorectal cancer cells

Junji Kawaguchi, Seiji Adachi, Ichiro Yasuda, Takahiro Yamauchi, Masanori Nakashima, Tomohiko Ohno, Masahito Shimizu, Takashi Yoshioka, Masahiko Itani, Osamu Kozawa, Hisataka Moriwaki

Genetic variants of p27 and p21 as predictors for risk of second primary malignancy in patients with index squamous cell carcinoma of head and neck

Zhongqiu Wang, Erich M Sturgis, Fenghua Zhang, Dapeng Lei, Zhensheng Liu, Li Xu, Xicheng Song, Qingyi Wei, Guojun Li

Interferon-α enhances antitumor activities of oncolytic adenovirus-mediated IL-24 expression in hepatocellular carcinoma

Cong-Jun Wang, Chao-Wen Xiao, Tian-Geng You, Ya-Xin Zheng, Wei Gao, Zhu-Qing Zhou, Jun Chen, Xin-Bo Xue, Jia Fan, Hui Zhang

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