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PLOS Genetics

ISSN Print: 1553-7390

ISSN Online:

主页: http://www.plosgenetics.org/article/browse/volume

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The Molecular Mechanisms of OPA1-Mediated Optic Atrophy in Drosophila Model and Prospects for Antioxidant Treatment

Will Yarosh,Jessica Monserrate,James Jiayuan Tong,Stephanie Tse,Phung Khanh Le,Kimberly Nguyen,Carrie B Brachmann,Douglas C Wallace,Taosheng Huang

Analysis and Application of European Genetic Substructure Using 300 K SNP Information

Chao Tian,Robert M Plenge,Michael Ransom,Annette Lee,Pablo Villoslada,Carlo Selmi,Lars Klareskog,Ann E Pulver,Lihong Qi,Peter K Gregersen,Michael F Seldin

Application of Ancestry Informative Markers to Association Studies in European Americans

Michael F Seldin ,Alkes L Price

TERT Promotes Epithelial Proliferation through Transcriptional Control of a Myc- and Wnt-Related Developmental Program

Jinkuk Choi,Lucinda K Southworth,Kavita Y Sarin,Andrew S Venteicher,Wenxiu Ma,Woody Chang,Peggie Cheung,Sohee Jun,Maja K Artandi,Naman Shah,Stuart K Kim,Steven E Artandi

Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics

Montserrat Garcia-Closas ,Per Hall,Heli Nevanlinna,Karen Pooley,Jonathan Morrison,Douglas A. Richesson,Stig E. Bojesen,B？rge G. Nordestgaard,Christen K. Axelsson,Jose I. Arias,Roger L. Milne,Gloria Ribas,Anna González-Neira,Javier Benítez,Pilar Zamora,Hiltrud Brauch,Christina Justenhoven,Ute Hamann,Yon-Dschun Ko,Thomas Bruening,Susanne Haas,Thilo D？rk,Peter Schürmann,Peter Hillemanns,Natalia Bogdanova,Michael Bremer,Johann Hinrich Karstens,Rainer Fagerholm,Kirsimari Aaltonen,Kristiina Aittom？ki,Karl von Smitten,Carl Blomqvist,Arto Mannermaa,Matti Uusitupa,Matti Eskelinen,Maria Tengstr？m,Veli-Matti Kosma,Vesa Kataja,Georgia Chenevix-Trench,Amanda B. Spurdle,Jonathan Beesley,Xiaoqing Chen,Australian Ovarian Cancer Management Group,The Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer,Peter Devilee,Christi J. van Asperen,Catharina E. Jacobi,Rob A. E. M. Tollenaar,Petra E.A. Huijts,Jan G. M. Klijn,Jenny Chang-Claude,Silke Kropp,Tracy Slanger,Dieter Flesch-Janys,Elke Mutschelknauss,Ramona Salazar,Shan Wang-Gohrke,Fergus Couch,Ellen L. Goode,Janet E. Olson,Celine Vachon,Zachary S. Fredericksen,Graham G. Giles,Laura Baglietto,Gianluca Severi,John L. Hopper,Dallas R. English,Melissa C. Southey,Christopher A. Haiman,Brian E. Henderson,Laurence N. Kolonel,Loic Le Marchand,Daniel O. Stram,David J. Hunter,Susan E. Hankinson,David G. Cox,Rulla Tamimi,Peter Kraft,Mark E. Sherman,Stephen J. Chanock,Jolanta Lissowska,Louise A. Brinton,Beata Peplonska

A Bacterial Kind of Aging

Thomas Nystr？m

Argonaute2 Is Essential for Mammalian Gastrulation and Proper Mesoderm Formation

Reid S Alisch,Peng Jin,Michael Epstein,Tamara Caspary,Stephen T Warren

POF and HP1 Bind Expressed Exons, Suggesting a Balancing Mechanism for Gene Regulation

Anna-Mia Johansson,Per Stenberg,Fredrik Pettersson,Jan Larsson

A Mechanism Misregulating p27 in Tumors Discovered in a Functional Genomic Screen

Carrie M Garrett-Engele,Michael A Tasch,Harry C Hwang,Matthew L Fero,Roger M Perlmutter,Bruce E Clurman,James M Roberts

A Tribute to Marcy Carlson Speer, 1959–2007

Suzanne M Leal

Sustained Post-Mating Response in Drosophila melanogaster Requires Multiple Seminal Fluid Proteins

K. Ravi Ram,Mariana F Wolfner

Developmental Role and Regulation of cortex, a Meiosis-Specific Anaphase-Promoting Complex/Cyclosome Activator

Jillian A Pesin,Terry L Orr-Weaver

C. elegans Germ Cells Switch between Distinct Modes of Double-Strand Break Repair During Meiotic Prophase Progression

Michiko Hayashi,Gregory M Chin,Anne M Villeneuve

Entropy Explains Aging, Genetic Determinism Explains Longevity, and Undefined Terminology Explains Misunderstanding Both

Leonard Hayflick

Lessons from “Lower” Organisms: What Worms, Flies, and Zebrafish Can Teach Us about Human Energy Metabolism

Amnon Schlegel ,Didier Y. R Stainier

αADα Hybrids of Cryptococcus neoformans: Evidence of Same-Sex Mating in Nature and Hybrid Fitness

Xiaorong Lin,Anastasia P Litvintseva,Kirsten Nielsen,Sweta Patel,Anna Floyd,Thomas G Mitchell,Joseph Heitman

Linkage Analysis of a Model Quantitative Trait in Humans: Finger Ridge Count Shows Significant Multivariate Linkage to 5q14.1

Sarah E Medland ,Danuta Z Loesch,Bogdan Mdzewski,Gu Zhu,Grant W Montgomery,Nicholas G Martin

Correction: Mouse Pachytene Checkpoint 2 (Trip13) Is Required for Completing Meiotic Recombination but Not Synapsis

Xin Chenglin Li,John C Schimenti

Correction: The Genographic Project Public Participation Mitochondrial DNA Database

Doron M. Behar,Saharon Rosset,Jason Blue-Smith,Oleg Balanovsky,Shay Tzur,David Comas,R. John Mitchell,Lluis Quintana-Murci,Chris Tyler-Smith,R. Spencer Wells,The Genographic Consortium

Inconsistencies in Neanderthal Genomic DNA Sequences

Jeffrey D Wall ,Sung K Kim

Telomeric Trans-Silencing: An Epigenetic Repression Combining RNA Silencing and Heterochromatin Formation

Thibaut Josse,Laure Teysset,Anne-Laure Todeschini,Clara M Sidor,Dominique Anxolabéhère,Stéphane Ronsseray

Genetics of Aging in Caenorhabditis elegans

Adam Antebi

Genome Analysis of Minibacterium massiliensis Highlights the Convergent Evolution of Water-Living Bacteria

Stéphane Audic ,Catherine Robert,Bernard Campagna,Hugues Parinello,Jean-Michel Claverie,Didier Raoult,Michel Drancourt

Global Dissemination of a Single Mutation Conferring White Pericarp in Rice

Megan T Sweeney,Michael J Thomson,Yong Gu Cho,Yong Jin Park,Scott H Williamson,Carlos D Bustamante,Susan R McCouch

Correction: COUP-TFII Mediates Progesterone Regulation of Uterine Implantation by Controlling ER Activity

Isao Kurihara,Dong-Kee Lee,Fabrice G Petit,Jaewook Jeong,Kevin Lee,John P Lydon,Francesco J DeMayo,Ming-Jer Tsai,Sophia Y Tsai

“Myc’ed Messages”: Myc Induces Transcription of E2F1 while Inhibiting Its Translation via a microRNA Polycistron

Hilary A Coller ,Joshua J Forman,Aster Legesse-Miller

Genetic Determinants of Human Health Span and Life Span: Progress and New Opportunities

George M Martin ,Aviv Bergman,Nir Barzilai

The Multiple Roles of Mps1 in Drosophila Female Meiosis

William D Gilliland,Stacie E Hughes,Jeffrey L Cotitta,Satomi Takeo,Youbin Xiang,R. Scott Hawley

Modulating the Expression of Disease Genes with RNA-Based Therapy

Matthew Wood ,Haifang Yin,Graham McClorey

Cis- and Trans-Acting Elements Regulate the Mouse Psmb9 Meiotic Recombination Hotspot

Frédéric Baudat,Bernard de Massy

Correction: Discovery and Analysis of Evolutionarily Conserved Intronic Splicing Regulatory Elements

Gene W Yeo,Eric L. Van Nostrand,Tiffany Y Liang

X Chromosome Reactivation Initiates in Nascent Primordial Germ Cells in Mice

Michihiko Sugimoto,Kuniya Abe

Drosophila SETDB1 Is Required for Chromosome 4 Silencing

Carole Seum,Emanuela Reo,Hongzhuang Peng,Frank J Rauscher III,Pierre Spierer,Séverine Bontron

A Mutation in the Myostatin Gene Increases Muscle Mass and Enhances Racing Performance in Heterozygote Dogs

Dana S Mosher,Pascale Quignon,Carlos D Bustamante,Nathan B Sutter,Cathryn S Mellersh,Heidi G Parker,Elaine A Ostrander

Arabidopsis TFL2/LHP1 Specifically Associates with Genes Marked by Trimethylation of Histone H3 Lysine 27

Franziska Turck equal contributor,Fran？ois Roudier equal contributor,Sara Farrona,Marie-Laure Martin-Magniette,Elodie Guillaume,Nicolas Buisine,Séverine Gagnot,Robert A Martienssen,George Coupland ,Vincent Colot

Selection for Robustness in Mutagenized RNA Viruses

Rafael Sanjuán equal contributor,José M Cuevas equal contributor,Victoria Furió,Edward C Holmes,Andrés Moya

Dietary Restriction in Drosophila: Delayed Aging or Experimental Artefact?

Matthew D. W Piper,Linda Partridge

Mitotic Recombination Accelerates Adaptation in the Fungus Aspergillus nidulans

Sijmen E Schoustra,Alfons J. M Debets,Marijke Slakhorst,Rolf F Hoekstra

Off the Beaten Path: An Interview with Spencer Wells

Jane Gitschier

Forward-Time Simulations of Human Populations with Complex Diseases

Bo Peng ,Christopher I Amos,Marek Kimmel

New Small Nuclear RNA Gene-Like Transcriptional Units as Sources of Regulatory Transcripts

Aldo Pagano ,Manuele Castelnuovo,Federico Tortelli,Roberto Ferrari,Giorgio Dieci,Ranieri Cancedda

Live Hot, Die Young: Transmission Distortion in Recombination Hotspots

Graham Coop equal contributor,Simon R Myers equal contributor

An Age-Old Problem

Nicholas Katsanis ,Susan M Rosenberg

Correction: Mammalian Small Nucleolar RNAs Are Mobile Genetic Elements

Michel J Weber

Elevated Rates of Sister Chromatid Exchange at Chromosome Ends

M. Katharine Rudd,Cynthia Friedman,Sean S Parghi,Elena V Linardopoulou,Li Hsu,Barbara J Trask

A Role for Alstr？m Syndrome Protein, Alms1, in Kidney Ciliogenesis and Cellular Quiescence

Guochun Li,Raquel Vega,Keats Nelms,Nicholas Gekakis,Christopher Goodnow,Peter McNamara,Hua Wu,Nancy A Hong,Richard Glynne

Scrambling Eggs in Plastic Bottles

R. Scott Hawley ,Dorothy Warburton

A Role for the Adult Fat Body in Drosophila Male Courtship Behavior

Anna A Lazareva,Gregg Roman,William Mattox,Paul E Hardin,Brigitte Dauwalder

The Role of Mitochondrial DNA Mutations in Mammalian Aging

Gregory C Kujoth,Patrick C Bradshaw,Suraiya Haroon,Tomas A Prolla

A Screen for Recessive Speciation Genes Expressed in the Gametes of F1 Hybrid Yeast

Duncan Greig

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