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PLOS ONE

ISSN Print: 1932-6203

ISSN Online:

主页: http://www.plosone.org/

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The Immune System GTPase GIMAP6 Interacts with the Atg8 Homologue GABARAPL2 and Is Recruited to Autophagosomes

John C. Pascall, Sergio Rotondo, Aamir S. Mukadam, David Oxley, Judith Webster, Simon A. Walker, Jerry Piron, Christine Carter, Nicholas T. Ktistakis, Geoffrey W. Butcher

A Population Pharmacokinetic and Pharmacodynamic Analysis of Peginesatide in Patients with Chronic Kidney Disease on Dialysis

Himanshu Naik, Max C. Tsai, Jill Fiedler-Kelly, Ping Qiu, Majid Vakilynejad

Yield Trends Are Insufficient to Double Global Crop Production by 2050

Deepak K. Ray, Nathaniel D. Mueller, Paul C. West, Jonathan A. Foley

Tectorigenin Attenuates Palmitate-Induced Endothelial Insulin Resistance via Targeting ROS-Associated Inflammation and IRS-1 Pathway

Qi Wang, Xiao-Lan Cheng, Dong-Yan Zhang, Xue-Jiao Gao, Ling Zhou, Xiao-Ying Qin, Guo-Yong Xie, Kang Liu, Yong Qin, Bao-Lin Liu, Min-Jian Qin

Oxidative Stress and Erythrocyte Membrane Alterations in Children with Autism: Correlation with Clinical Features

Alessandro Ghezzo, Paola Visconti, Provvidenza M. Abruzzo, Alessandra Bolotta, Carla Ferreri, Giuseppe Gobbi, Gemma Malisardi, Stefano Manfredini, Marina Marini, Laura Nanetti, Emanuela Pipitone, Francesca Raffaelli, Federica Resca, Arianna Vignini, Laura Mazzanti

Chemotherapeutic Potential of 2-[Piperidinoethoxyphenyl]-3-Phenyl-2H-Benzo(b)pyran in Estrogen Receptor- Negative Breast Cancer Cells: Action via Prevention of EGFR Activation and Combined Inhibition of PI-3-K/Akt/FOXO and MEK/Erk/AP-1 Pathways

Ruchi Saxena, Vishal Chandra, Murli Manohar, Kanchan Hajela, Utsab Debnath, Yenamandra S. Prabhakar, Karan Singh Saini, Rituraj Konwar, Sandeep Kumar, Kaling Megu, Bal Gangadhar Roy, Anila Dwivedi

Joint Association of Dietary Pattern and Physical Activity Level with Cardiovascular Disease Risk Factors among Chinese Men: A Cross-Sectional Study

Dong Wang, Yuna He, Yanping Li, Dechun Luan, Fengying Zhai, Xiaoguang Yang, Guansheng Ma

A Low Temperature Limit for Life on Earth

Andrew Clarke, G. John Morris, Fernanda Fonseca, Benjamin J. Murray, Elizabeth Acton, Hannah C. Price

Contagion of Cooperation in Static and Fluid Social Networks

Jillian J. Jordan, David G. Rand, Samuel Arbesman, James H. Fowler, Nicholas A. Christakis

Influenza Illness and Hospitalizations Averted by Influenza Vaccination in the United States, 2005–2011

Deliana Kostova, Carrie Reed, Lyn Finelli, Po-Yung Cheng, Paul M. Gargiullo, David K. Shay, James A. Singleton, Martin I. Meltzer, Peng-jun Lu, Joseph S. Bresee

Uncontacted Waorani in the Yasuní Biosphere Reserve: Geographical Validation of the Zona Intangible Tagaeri Taromenane (ZITT)

Salvatore Eugenio Pappalardo, Massimo De Marchi, Francesco Ferrarese

Dietary N-Carbamylglutamate Supplementation Boosts Intestinal Mucosal Immunity in Escherichia coli Challenged Piglets

Fengrui Zhang, Xiangfang Zeng, Fengjuan Yang, Zhimin Huang, Hong Liu, Xi Ma, Shiyan Qiao

CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5′-Diphosphate Ribose Template

Christelle Moreau, Qun Liu, Richard Graeff, Gerd K. Wagner, Mark P. Thomas, Joanna M. Swarbrick, Satoshi Shuto, Hon Cheung Lee, Quan Hao, Barry V. L. Potter

TGF-beta1 Does Not Induce Senescence of Multipotent Mesenchymal Stromal Cells and Has Similar Effects in Early and Late Passages

Gudrun Walenda, Khalid Abnaof, Sylvia Joussen, Steffen Meurer, Hubert Smeets, Bj？rn Rath, Kurt Hoffmann, Holger Fr？hlich, Martin Zenke, Ralf Weiskirchen, Wolfgang Wagner

Longitudinal Assessment of Amyloid Pathology in Transgenic ArcAβ Mice Using Multi-Parametric Magnetic Resonance Imaging

Jan Klohs, Igna Wojtyna Politano, Andreas Deistung, Joanes Grandjean, Anna Drewek, Marco Dominietto, Ruth Keist, Ferdinand Schweser, Jürgen R. Reichenbach, Roger M. Nitsch, Irene Knuesel, Markus Rudin

T Cell Activation and Cytokine Profile of Tuberculosis and HIV-Positive Individuals during Antituberculous Treatment and Efavirenz-Based Regimens

Tatiana P. da Silva, Carmem B. W. Giacoia-Gripp, Carolina A. Schmaltz, Flavia M. Sant` Anna, Valeria Rolla, Mariza G. Morgado

Early Root Herbivory Impairs Arbuscular Mycorrhizal Fungal Colonization and Shifts Defence Allocation in Establishing Plantago lanceolata

Alison E. Bennett, Anna M. Macrae, Ben D. Moore, Sandra Caul, Scott N. Johnson

Islet-1 May Function as an Assistant Factor for Histone Acetylation and Regulation of Cardiac Development-Related Transcription Factor Mef2c Expression

Zhongsu Yu, Juanjuan Kong, Bo Pan, Huichao Sun, Tiewei Lv, Jing Zhu, Guoying Huang, Jie Tian

Prevalence of Dementia and Subtypes in Valladolid, Northwestern Spain: The DEMINVALL Study

Miguel Angel Tola-Arribas, María Isabel Yugueros, María José Garea, Fernando Ortega-Valín, Ana Cerón-Fernández, Beatriz Fernández-Malvido, Antonio San José-Gallegos, Marta González-Touya, Ana Botrán-Velicia, Vanessa Iglesias-Rodríguez, Bárbara Díaz-Gómez

IL-10 Modulates In Vitro Multinucleate Giant Cell Formation in Human Tuberculosis

Parul Shrivastava, Tamishraha Bagchi

The Transcription Factor MAZR Preferentially Acts as a Transcriptional Repressor in Mast Cells and Plays a Minor Role in the Regulation of Effector Functions in Response to FcεRI Stimulation

Anastasia Abramova, Shinya Sakaguchi, Alexandra Schebesta, Hammad Hassan, Nicole Boucheron, Peter Valent, Axel Roers, Wilfried Ellmeier

Increased Pro-Inflammatory Cytokines, C-Reactive Protein and Nerve Growth Factor Expressions in Serum of Patients with Interstitial Cystitis/Bladder Pain Syndrome

Yuan-Hong Jiang, Chung-Hsin Peng, Hsin-Tzu Liu, Hann-Chorng Kuo

Aberrant Crossed Corticospinal Facilitation in Muscles Distant from a Spinal Cord Injury

Karen L. Bunday, Martin Oudega, Monica A. Perez

Long-Term Potentiation Promotes Proliferation/Survival and Neuronal Differentiation of Neural Stem/Progenitor Cells

Taesup Cho, Jae K. Ryu, Changiz Taghibiglou, Yuan Ge, Allen W. Chan, Lidong Liu, Jie Lu, James G. McLarnon, Yu Tian Wang

Impact of Article Language in Multi-Language Medical Journals - a Bibliometric Analysis of Self-Citations and Impact Factor

Torsten Diekhoff, Peter Schlattmann, Marc Dewey

The Projection of Burden of Disease in Islamic Republic of Iran to 2025

Razieh Khajehkazemi, Behnam Sadeghirad, Mohammad Karamouzian, Mohammad-Sadegh Fallah, Mohammad-Hossien Mehrolhassani, Reza Dehnavieh, AliAkbar Haghdoost

Surface Roughness Detection of Arteries via Texture Analysis of Ultrasound Images for Early Diagnosis of Atherosclerosis

Lili Niu, Ming Qian, Wei Yang, Long Meng, Yang Xiao, Kelvin K. L. Wong, Derek Abbott, Xin Liu, Hairong Zheng

Chronic Inhibition, Self-Control and Eating Behavior: Test of a ‘Resource Depletion’ Model

Martin S. Hagger, Giulia Panetta, Chung-Ming Leung, Ging Ging Wong, John C. K. Wang, Derwin K. C. Chan, David A. Keatley, Nikos L. D. Chatzisarantis

Effects of Taurine Supplementation on Hepatic Markers of Inflammation and Lipid Metabolism in Mothers and Offspring in the Setting of Maternal Obesity

Minglan Li, Clare M. Reynolds, Deborah M. Sloboda, Clint Gray, Mark H. Vickers

Cholesterol Diet Withdrawal Leads to an Initial Plaque Instability and Subsequent Regression of Accelerated Iliac Artery Atherosclerosis in Rabbits

Vivek Khanna, Manish Jain, Vishal Singh, Jitendra S. Kanshana, Prem Prakash, Manoj K. Barthwal, Puvvada S. R. Murthy, Madhu Dikshit

Systematic Identification of Gene Families for Use as “Markers” for Phylogenetic and Phylogeny-Driven Ecological Studies of Bacteria and Archaea and Their Major Subgroups

Dongying Wu, Guillaume Jospin, Jonathan A. Eisen

Glycogen Content Regulates Peroxisome Proliferator Activated Receptor-？ (PPAR-？) Activity in Rat Skeletal Muscle

Andrew Philp, Matthew G. MacKenzie, Micah Y. Belew, Mhairi C. Towler, Alan Corstorphine, Angela Papalamprou, D. Grahame Hardie, Keith Baar

The Tumor Suppressor Gene TUSC2 (FUS1) Sensitizes NSCLC to the AKT Inhibitor MK2206 in LKB1-dependent Manner

Jieru Meng, Mourad Majidi, Bingliang Fang, Lin Ji, B. Nebiyou Bekele, John D. Minna, Jack A. Roth

Duffy Antigen Receptor for Chemokines Regulates Post-Fracture Inflammation

Charles H. Rundle, Subburaman Mohan, Bouchra Edderkaoui

Cell Infectivity in Relation to Bovine Leukemia Virus gp51 and p24 in Bovine Milk Exosomes

Tetsuya Yamada, Hiroaki Shigemura, Naotaka Ishiguro, Yasuo Inoshima

Prevalence and Trends of the Abdominal Aortic Aneurysms Epidemic in General Population - A Meta-Analysis

Xi Li, Ge Zhao, Jian Zhang, Zhiquan Duan, Shijie Xin

Protein Phosphatases Decrease Their Activity during Capacitation: A New Requirement for This Event

Janetti R. Signorelli, Emilce S. Díaz, Karla Fara, Lina Barón, Patricio Morales

Efficacy and Safety of Dihydroartemisinin-Piperaquine for Treatment of Plasmodium vivax Malaria in Endemic Countries: Meta-Analysis of Randomized Controlled Studies

Cho Naing, Vanessa Racloz, Maxine Anne Whittaker, Kyan Aung, Simon Andrew Reid, Joon Wah Mak, Marcel Tanner

Megafaunal Communities in Rapidly Warming Fjords along the West Antarctic Peninsula: Hotspots of Abundance and Beta Diversity

Laura J. Grange, Craig R. Smith

Elevated Frequencies of Circulating Th22 Cell in Addition to Th17 Cell and Th17/Th1 Cell in Patients with Acute Coronary Syndrome

Lei Zhang, Ting Wang, Xiao-qi Wang, Rui-zhi Du, Kai-ning Zhang, Xin-guang Liu, Dao-xin Ma, Shuang Yu, Guo-hai Su, Zhen-hua Li, Yu-qing Guan, Nai-li Du

Methylation of the SLC6a2 Gene Promoter in Major Depression and Panic Disorder

Richard Bayles, Emma K. Baker, Jeremy B. M. Jowett, David Barton, Murray Esler, Assam El-Osta, Gavin Lambert

The Contribution of Head Movement to the Externalization and Internalization of Sounds

W. Owen Brimijoin, Alan W. Boyd, Michael A. Akeroyd

Vitamin A Deficiency Impairs Adaptive B and T Cell Responses to a Prototype Monovalent Attenuated Human Rotavirus Vaccine and Virulent Human Rotavirus Challenge in a Gnotobiotic Piglet Model

Kuldeep S. Chattha, Sukumar Kandasamy, Anastasia N. Vlasova, Linda J. Saif

The Mitochondrial Genome of Arctica islandica; Phylogeny and Variation

Gernot Gl？ckner, Ivonne Heinze, Matthias Platzer, Christoph Held, Doris Abele

A Quality Control Mechanism Linking Meiotic Success to Release of Ascospores

Haiyan Guo, Megan C. King

Neuropilar Projections of the Anterior Gastric Receptor Neuron in the Stomatogastric Ganglion of the Jonah Crab, Cancer Borealis

Marie L. Goeritz, Matthew R. Bowers, Brian Slepian, Eve Marder

Chikungunya as a Cause of Acute Febrile Illness in Southern Sri Lanka

Megan E. Reller, Ufuoma Akoroda, Ajith Nagahawatte, Vasantha Devasiri, Wasantha Kodikaarachchi, John J. Strouse, Robert Chua, Yan'an Hou, Angelia Chow, October M. Sessions, Truls ？stbye, Duane J. Gubler, Christopher W. Woods, Champica Bodinayake

Estimation of the Fraction of Cancer Cells in a Tumor DNA Sample Using DNA Methylation

Takamasa Takahashi, Yasunori Matsuda, Satoshi Yamashita, Naoko Hattori, Ryoji Kushima, Yi-Chia Lee, Hiroyasu Igaki, Yuji Tachimori, Masato Nagino, Toshikazu Ushijima

Development of a Consensus Taxonomy of Sedentary Behaviors (SIT): Report of Delphi Round 1

Sebastien Francois Martin Chastin, Ulf Schwarz, Dawn Ann Skelton

A Daily Oscillation in the Fundamental Frequency and Amplitude of Harmonic Syllables of Zebra Finch Song

William E. Wood, Peter J. Osseward, Thomas K. Roseberry, David J. Perkel

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