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PLOS ONE

ISSN Print: 1932-6203

ISSN Online:

主页: http://www.plosone.org/

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Pre-Clinical Evaluation of a Novel Nanoemulsion-Based Hepatitis B Mucosal Vaccine

Paul E. Makidon, Anna U. Bielinska, Shraddha S. Nigavekar, Katarzyna W. Janczak, Jessica Knowlton, Alison J. Scott, Nicholas Mank, Zhengyi Cao, Sivaprakash Rathinavelu, Michael R. Beer, J. Erby Wilkinson, Luz P. Blanco, Jeffrey J. Landers, James R. Baker

Oil and Gas Projects in the Western Amazon: Threats to Wilderness, Biodiversity, and Indigenous Peoples

Matt Finer, Clinton N. Jenkins, Stuart L. Pimm, Brian Keane, Carl Ross

Phase 1 Trial of AMA1-C1/Alhydrogel plus CPG 7909: An Asexual Blood-Stage Vaccine for Plasmodium falciparum Malaria

Gregory E. D. Mullen, Ruth D. Ellis, Kazutoyo Miura, Elissa Malkin, Caroline Nolan, Mhorag Hay, Michael P. Fay, Allan Saul, Daming Zhu, Kelly Rausch, Samuel Moretz, Hong Zhou, Carole A. Long, Louis H. Miller, John Treanor

A Detailed Analysis of the Murine TAP Transporter Substrate Specificity

Anne Burgevin, Loredana Saveanu, Yohan Kim, émilie Barilleau, Maya Kotturi, Alessandro Sette, Peter van Endert, Bjoern Peters

P68 RNA Helicase (DDX5) Alters Activity of Cis- and Trans-Acting Factors of the Alternative Splicing of H-Ras

Maria Camats, Sonia Guil, Mariette Kokolo, Montse Bach-Elias

Pattern of the Divergence of Olfactory Receptor Genes during Tetrapod Evolution

Takushi Kishida

Serum Alpha-Fetoprotein Predicts Treatment Outcome in Chronic Hepatitis C Patients Regardless of HCV Genotype

Hendy Abdoul, Vincent Mallet, Stanislas Pol, Arnaud Fontanet

Effects of Experimental Brood Size Manipulation and Gender on Carotenoid Levels of Eurasian Kestrels Falco tinnunculus

Toni Laaksonen, Juan J. Negro, Sami Lyytinen, Jari Valkama, Indrek Ots, Erkki Korpim？ki

Are There Better Methods of Monitoring MRSA Control than Bacteraemia Surveillance? An Observational Database Study

Sarah Walker, Tim E. A. Peto, Lily O'Connor, Derrick W. Crook, David Wyllie

Divergent Pathways in COS-7 Cells Mediate Defective Internalization and Intracellular Routing of Truncated G-CSFR Forms in SCN/AML

Melissa G. Hunter, Morgan McLemore, Daniel C. Link, Megan Loveland, Alexander Copelan, Belinda R. Avalos

Moderate Alcohol Use and Mortality from Ischaemic Heart Disease: A Prospective Study in Older Chinese People

C. Mary Schooling, Sun Wenjie, Sai Yin Ho, Wai Man Chan, May Ked Tham, Kin Sang Ho, Gabriel M. Leung, Tai Hing Lam

HyperISGylation of Old World Monkey ISG15 in Human Cells

Els Pattyn, Annick Verhee, Isabel Uyttendaele, Julie Piessevaux, Evy Timmerman, Kris Gevaert, Jo？l Vandekerckhove, Frank Peelman, Jan Tavernier

Molecular Evolution of Human Immunodeficiency Virus Type 1 upon Transmission between Human Leukocyte Antigen Disparate Donor-Recipient Pairs

Marjon Navis, Diana Edo Matas, Andrea Rachinger, Fransje A. Koning, Peter van Swieten, Neeltje A. Kootstra, Hanneke Schuitemaker

Alternative Promoters Influence Alternative Splicing at the Genomic Level

Dedong Xin, Landian Hu, Xiangyin Kong

Chromosomal Instability by Inefficient Mps1 Auto-Activation Due to a Weakened Mitotic Checkpoint and Lagging Chromosomes

Nannette Jelluma, Arjan B. Brenkman, Ian McLeod, John R. Yates, Don W. Cleveland, René H. Medema, Geert J. P. L. Kops

Disturbance of Social Hierarchy by an Invasive Species: A Gene Transcription Study

Christian Roberge, Simon Blanchet, Julian J. Dodson, Helga Guderley, Louis Bernatchez

An Analysis of News Media Coverage of Complementary and Alternative Medicine

Billie Bonevski, Amanda Wilson, David A. Henry

Germline Mutation in RNASEL Predicts Increased Risk of Head and Neck, Uterine Cervix and Breast Cancer

Bo Eskerod Madsen, Eliana Marisa Ramos, Mathieu Boulard, Katarzyna Duda, Jens Overgaard, Marianne Nordsmark, Carsten Wiuf, Lise Lotte Hansen

B-MYB Is Essential for Normal Cell Cycle Progression and Chromosomal Stability of Embryonic Stem Cells

Kirill V. Tarasov, Yelena S. Tarasova, Wai Leong Tam, Daniel R. Riordon, Steven T. Elliott, Gabriela Kania, Jinliang Li, Satoshi Yamanaka, David G. Crider, Gianluca Testa, Ronald A. Li, Bing Lim, Colin L. Stewart, Yie Liu, Jennifer E. Van Eyk, Robert P. Wersto, Anna M. Wobus, Kenneth R. Boheler

TSP-1 Secreted by Bone Marrow Stromal Cells Contributes to Retinal Ganglion Cell Neurite Outgrowth and Survival

Keming Yu, Jian Ge, James Bradley Summers, Fan Li, Xuan Liu, Ping Ma, Joseph Kaminski, Jing Zhuang

Altered Gene Expression in Early Atherosclerosis Is Blocked by Low Level Apolipoprotein E

Yanqing Ma, Craig C. Malbon, David L. Williams, Fayanne E. Thorngate

Free Brick1 Is a Trimeric Precursor in the Assembly of a Functional Wave Complex

Emmanuel Derivery, Jenny Fink, Davy Martin, Anne Houdusse, Matthieu Piel, Theresia E. Stradal, Daniel Louvard, Alexis Gautreau

Perinatal Androgens and Adult Behavior Vary with Nestling Social System in Siblicidal Boobies

Martina S. Müller, Julius F. Brennecke, Elaine T. Porter, Mary Ann Ottinger, David J. Anderson

HER2 Oncogenic Function Escapes EGFR Tyrosine Kinase Inhibitors via Activation of Alternative HER Receptors in Breast Cancer Cells

Anthony Kong, Véronique Calleja, Pierre Leboucher, Adrian Harris, Peter J. Parker, Banafshé Larijani

Non-Replication of Genome-Wide Based Associations between Common Variants in INSIG2 and PFKP and Obesity in Studies of 18,014 Danes

Camilla H. Andreasen, Mette S. Mogensen, Knut Borch-Johnsen, Annelli Sandb？k, Torsten Lauritzen, Thorkild I. A. S？rensen, Lars Hansen, Katrine Almind, Torben J？rgensen, Oluf Pedersen, Torben Hansen

Riluzole Increases the Amount of Latent HSF1 for an Amplified Heat Shock Response and Cytoprotection

Jingxian Yang, Kristen Bridges, Kuang Yu Chen, Alice Y.-C. Liu

Improving T-Cell Assays for the Diagnosis of Latent TB Infection: Potential of a Diagnostic Test Based on IP-10

Morten Ruhwald, Janne Petersen, Kristian Kofoed, Hiroshi Nakaoka, Luis Eduardo Cuevas, Lovett Lawson, Stephen Bertil Squire, Jesper Eugen-Olsen, Pernille Ravn

Liposomal Co-Entrapment of CD40mAb Induces Enhanced IgG Responses against Bacterial Polysaccharide and Protein

Caterina Hatzifoti, Andrew Bacon, Helen Marriott, Peter Laing, Andrew W. Heath

Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition

Anne-Pierre Morel, Marjory Lièvre, Clémence Thomas, George Hinkal, Stéphane Ansieau, Alain Puisieux

Boc5, a Non-Peptidic Glucagon-Like Peptide-1 Receptor Agonist, Invokes Sustained Glycemic Control and Weight Loss in Diabetic Mice

Haoran Su, Min He, Hongmei Li, Qing Liu, Jia Wang, Yiqian Wang, Weiwei Gao, Ling Zhou, Jiayu Liao, Andrew A. Young, Ming-Wei Wang

Neuromagnetic Evidence for Early Auditory Restoration of Fundamental Pitch

Philip J. Monahan, Kevin de Souza, William J. Idsardi

The Effectiveness of a Home Care Program for Supporting Caregivers of Persons with Dementia in Developing Countries: A Randomised Controlled Trial from Goa, India

Amit Dias, Michael E. Dewey, Jean D'Souza, Rajesh Dhume, Dilip D. Motghare, K. S. Shaji, Rajiv Menon, Martin Prince, Vikram Patel

Synergistic and Additive Effects of Hydrostatic Pressure and Growth Factors on Tissue Formation

Benjamin D. Elder, Kyriacos A. Athanasiou

Functional Diversification of Paralogous Transcription Factors via Divergence in DNA Binding Site Motif and in Expression

Larry N. Singh, Sridhar Hannenhalli

Promiscuous Expression of H2B-GFP Transgene in Hematopoietic Stem Cells

Grant A. Challen, Margaret A. Goodell

Foxc Transcription Factors Directly Regulate Dll4 and Hey2 Expression by Interacting with the VEGF-Notch Signaling Pathways in Endothelial Cells

Hisaki Hayashi, Tsutomu Kume

Model for the Peptide-Free Conformation of Class II MHC Proteins

Corrie A. Painter, Anthony Cruz, Gustavo E. López, Lawrence J. Stern, Zarixia Zavala-Ruiz

Epigenetic Regulation of the Mammalian Cell

Keith Baverstock, Mauno R？nkk？

The Polycomb Protein and E3 Ubiquitin Ligase Ring1B Harbors an IRES in its Highly Conserved 5′ UTR

Erwin Boutsma, Sonja Noback, Maarten van Lohuizen

Intestinal Colonization of IL-2 Deficient Mice with Non-Colitogenic B. vulgatus Prevents DC Maturation and T-Cell Polarization

Martina Müller, Kerstin Fink, Julia Geisel, Frauke Kahl, Burghardt Jilge, J？rg Reimann, Nicolas Mach, Ingo B. Autenrieth, Julia S. Frick

Deciphering the Ubiquitin-Mediated Pathway in Apicomplexan Parasites: A Potential Strategy to Interfere with Parasite Virulence

Nadia Ponts, Jianfeng Yang, Duk-Won Doug Chung, Jacques Prudhomme, Thomas Girke, Paul Horrocks, Karine G. Le Roch

Identifying Alternative Hyper-Splicing Signatures in MG-Thymoma by Exon Arrays

Lilach Soreq, Adi Gilboa-Geffen, Sonia Berrih-Aknin, Paul Lacoste, Ariel Darvasi, Eyal Soreq, Hagai Bergman, Hermona Soreq

Proteomic Analysis of Ovarian Cancer Cells Reveals Dynamic Processes of Protein Secretion and Shedding of Extra-Cellular Domains

Vitor M. Fa？a, Aviva P. Ventura, Mathew P. Fitzgibbon, Sandra R. Pereira-Fa？a, Sharon J. Pitteri, Ann E. Green, Renee C. Ireton, Qing Zhang, Hong Wang, Kathy C. O'Briant, Charles W. Drescher, Michèl Schummer, Martin W. McIntosh, Beatrice S. Knudsen, Samir M. Hanash

Falls, Depression and Antidepressants in Later Life: A Large Primary Care Appraisal

Ngaire Kerse, Leon Flicker, Jon J. Pfaff, Brian Draper, Nicola T. Lautenschlager, Moira Sim, John Snowdon, Osvaldo P. Almeida

Group B Streptococcal β-Hemolysin/Cytolysin Directly Impairs Cardiomyocyte Viability and Function

Mary E. Hensler, Shigeki Miyamoto, Victor Nizet

MicroRNA Expression and Identification of Putative miRNA Targets in Ovarian Cancer

Neetu Dahiya, Cheryl A. Sherman-Baust, Tian-Li Wang, Ben Davidson, Ie-Ming Shih, Yongqing Zhang, William Wood, Kevin G. Becker, Patrice J. Morin

Temperature-Dependent Sex Determination in Fish Revisited: Prevalence, a Single Sex Ratio Response Pattern, and Possible Effects of Climate Change

Natalia Ospina-álvarez, Francesc Piferrer

Effect of Attenuation of Treg during BCG Immunization on Anti-Mycobacterial Th1 Responses and Protection against Mycobacterium tuberculosis

Barbara Jaron, Eddie Maranghi, Claude Leclerc, Laleh Majlessi

In Vivo-to-In Silico Iterations to Investigate Aeroallergen-Host Interactions

Alba Llop-Guevara, Marc Colangelo, Derek K. Chu, Cheryl Lynn Moore, Nicole A. Stieber, Tina D. Walker, Susanna Goncharova, Anthony J. Coyle, Lennart K. A. Lundblad, Paul M. O'Byrne, Miroslav Lovric, Manel Jordana

A Polyadenylation Factor Subunit Implicated in Regulating Oxidative Signaling in Arabidopsis thaliana

Jingxian Zhang, Balasubramanyam Addepalli, Kil-Young Yun, Arthur G. Hunt, Ruqiang Xu, Suryadevara Rao, Qingshun Q. Li, Deane L. Falcone

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