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PLOS ONE

ISSN Print: 1932-6203

ISSN Online:

主页: http://www.plosone.org/

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Single Cycle Structure-Based Humanization of an Anti-Nerve Growth Factor Therapeutic Antibody

Sonia Covaceuszach, Sara Marinelli, Ivet Krastanova, Gabriele Ugolini, Flaminia Pavone, Doriano Lamba, Antonino Cattaneo

Identifying Low pH Active and Lactate-Utilizing Taxa within Oral Microbiome Communities from Healthy Children Using Stable Isotope Probing Techniques

Jeffrey S. McLean, Sarah J. Fansler, Paul D. Majors, Kathleen McAteer, Lisa Z. Allen, Mark E. Shirtliff, Renate Lux, Wenyuan Shi

Genetic Diversity and Population Parameters of Sea Otters, Enhydra lutris, before Fur Trade Extirpation from 1741–1911

Shawn Larson, Ron Jameson, Michael Etnier, Terry Jones, Roberta Hall

Comparison of Serum HBsAg Quantitation by Four Immunoassays, and Relationships of HBsAg Level with HBV Replication and HBV Genotypes

Edouard Tuaillon, Anne-Marie Mondain, Nicolas Nagot, Laure Ottomani, Dramane Kania, Erika Nogue, Pierre-Alain Rubbo, Georges-Philippe Pageaux, Philippe Van de Perre, Jacques Ducos

Corvid Re-Caching without ‘Theory of Mind’: A Model

Elske van der Vaart, Rineke Verbrugge, Charlotte K. Hemelrijk

Common Variants in the Type 2 Diabetes KCNQ1 Gene Are Associated with Impairments in Insulin Secretion During Hyperglycaemic Glucose Clamp

Jana V. van Vliet-Ostaptchouk, Timon W. van Haeften, Gijs W. D. Landman, Erwin Reiling, Nanne Kleefstra, Henk J. G. Bilo, Olaf H. Klungel, Anthonius de Boer, Cleo C. van Diemen, Cisca Wijmenga, H. Marike Boezen, Jacqueline M. Dekker, Esther van 't Riet, Giel Nijpels, Laura M. C. Welschen, Hata Zavrelova, Elinda J. Bruin, Clara C. Elbers, Florianne Bauer, N. Charlotte Onland-Moret, Yvonne T. van der Schouw, Diederick E. Grobbee, Annemieke M. W. Spijkerman, Daphne L. van der A, Annemarie M. Simonis-Bik, Elisabeth M. W. Eekhoff, Michaela Diamant, Mark H. H. Kramer, Dorret I. Boomsma, Eco J. de Geus, Gonneke Willemsen, P. Eline Slagboom, Marten H. Hofker, Leen M. 't Hart

An Antagomir to MicroRNA Let7f Promotes Neuroprotection in an Ischemic Stroke Model

Amutha Selvamani, Pratheesh Sathyan, Rajesh C. Miranda, Farida Sohrabji

The Different Function of Single Phosphorylation Sites of Drosophila melanogaster Lamin Dm and Lamin C

Magdalena Zaremba-Czogalla, Katarzyna Piekarowicz, Katarzyna Wachowicz, Katarzyna Kozio？, Magda Dubińska-Magiera, Ryszard Rzepecki

Sensitivity of Calcification to Thermal Stress Varies among Genera of Massive Reef-Building Corals

Juan P. Carricart-Ganivet, Nancy Cabanillas-Terán, Israel Cruz-Ortega, Paul Blanchon

Placement of Leucine Zipper Motifs at the Carboxyl Terminus of HIV-1 Protease Significantly Reduces Virion Production

Yen-Yu Pan, Shiu-Mei Wang, Kuo-Jung Huang, Chien-Cheng Chiang, Chin-Tien Wang

Inhibition of the Intrinsic but Not the Extrinsic Apoptosis Pathway Accelerates and Drives Myc-Driven Tumorigenesis Towards Acute Myeloid Leukemia

Kari H？gstrand, Eduar Hejll, Birgitta Sander, Bj？rn Rozell, Lars-Gunnar Larsson, Alf Grandien

On Docking, Scoring and Assessing Protein-DNA Complexes in a Rigid-Body Framework

Marc Parisien, Karl F. Freed, Tobin R. Sosnick

Path Curvature Discrimination: Dependence on Gaze Direction and Optical Flow Speed

Colas N. Authié, Daniel R. Mestre

Exocyst Subunits Exo70 and Exo84 Cooperate with Small GTPases to Regulate Behavior and Endocytic Trafficking in C. elegans

Yaming Jiu, Congyu Jin, Yanbo Liu, Carina I. Holmberg, Jussi J？ntti

Sox10 Controls Migration of B16F10 Melanoma Cells through Multiple Regulatory Target Genes

Ikjoo Seong, Hyun Jung Min, Jung-Hyun Lee, Chang-Yeol Yeo, Dong Min Kang, Eok-Soo Oh, Eun Sook Hwang, Jaesang Kim

Chemical Composition and Antioxidant Activities of Broussonetia papyrifera Fruits

Jie Sun, Shao-fang Liu, Chu-shu Zhang, Li-na Yu, Jie Bi, Feng Zhu, Qing-li Yang

Adaptive Response in Mice Exposed to 900 MHz Radiofrequency Fields: Primary DNA Damage

Bingcheng Jiang, Jihua Nie, Zhen Zhou, Jie Zhang, Jian Tong, Yi Cao

FKBP12 Activates the Cardiac Ryanodine Receptor Ca2+-Release Channel and Is Antagonised by FKBP12.6

Elena Galfré, Samantha J. Pitt, Elisa Venturi, Mano Sitsapesan, Nathan R. Zaccai, Krasimira Tsaneva-Atanasova, Stephen O'Neill, Rebecca Sitsapesan

Divergent Pro-Inflammatory Profile of Human Dendritic Cells in Response to Commensal and Pathogenic Bacteria Associated with the Airway Microbiota

Jeppe Madura Larsen, Daniel Bisgaard Steen-Jensen, Janne Marie Laursen, Jonas N？rskov S？ndergaard, Hanieh Sadat Musavian, Tariq Mahmood Butt, Susanne Brix

Contrast in Edge Vegetation Structure Modifies the Predation Risk of Natural Ground Nests in an Agricultural Landscape

Nicole A. Schneider, Matthew Low, Debora Arlt, Tomas P？rt

High-Resolution Melting Analysis for the Rapid Detection of Fluoroquinolone and Streptomycin Resistance in Mycobacterium tuberculosis

Ann S. G. Lee, Danny C. T. Ong, Joshua C. L. Wong, Gilman K. H. Siu, Wing-Cheong Yam

Kin Selection and the Evolution of Social Information Use in Animal Conflict

Christopher C. M. Baker, Sasha R. X. Dall, Daniel J. Rankin

Models Analyses for Allelopathic Effects of Chicory at Equivalent Coupling of Nitrogen Supply and pH Level on F. arundinacea, T. repens and M. sativa

Quanzhen Wang, Bao Xie, Chunhui Wu, Guo Chen, Zhengwei Wang, Jian Cui, Tianming Hu, Pawel Wiatrak

Impartial Third-Party Interventions in Captive Chimpanzees: A Reflection of Community Concern

Claudia Rudolf von Rohr, Sonja E. Koski, Judith M. Burkart, Clare Caws, Orlaith N. Fraser, Angela Ziltener, Carel P. van Schaik

Transcriptomics Comparison between Porcine Adipose and Bone Marrow Mesenchymal Stem Cells during In Vitro Osteogenic and Adipogenic Differentiation

Elisa Monaco, Massimo Bionaz, Sandra Rodriguez-Zas, Walter L. Hurley, Matthew B. Wheeler

The Effects of Hydrogen Peroxide on the Circadian Rhythms of Microcystis aeruginosa

Haifeng Qian, Baolan Hu, Shuqiong Yu, Xiangjie Pan, Tao Wu, Zhengwei Fu

A Small World of Citations? The Influence of Collaboration Networks on Citation Practices

Matthew L. Wallace, Vincent Larivière, Yves Gingras

Evolutionary Dynamics of Fearfulness and Boldness: A Stochastic Simulation Model

Nan Lu, Ting Ji, Jia-Hua Zhang, Yue-Hua Sun, Yi Tao

Species History Masks the Effects of Human-Induced Range Loss – Unexpected Genetic Diversity in the Endangered Giant Mayfly Palingenia longicauda

Miklós Bálint, Kristóf Málnás, Carsten Nowak, Jutta Geismar, éva Váncsa, László Polyák, Szabolcs Lengyel, Peter Haase

Mutation of pescadillo Disrupts Oligodendrocyte Formation in Zebrafish

Timothy Simmons, Bruce Appel

Global Transcriptome Profiling of the Pine Shoot Beetle, Tomicus yunnanensis (Coleoptera: Scolytinae)

Jia-Ying Zhu, Ning Zhao, Bin Yang

In Vivo Diagnostic Imaging Using Micro-CT: Sequential and Comparative Evaluation of Rodent Models for Hepatic/Brain Ischemia and Stroke

Naoto Hayasaka, Nobuo Nagai, Naoyuki Kawao, Atsuko Niwa, Yoshichika Yoshioka, Yuki Mori, Hiroshi Shigeta, Nobuo Kashiwagi, Masaaki Miyazawa, Takao Satou, Hideaki Higashino, Osamu Matsuo, Takamichi Murakami

Historical Legacies in World Amphibian Diversity Revealed by the Turnover and Nestedness Components of Beta Diversity

Andrés Baselga, Carola Gómez-Rodríguez, Jorge M. Lobo

Respiratory Syncytial Virus NS1 Protein Colocalizes with Mitochondrial Antiviral Signaling Protein MAVS following Infection

Sandhya Boyapalle, Terianne Wong, Julio Garay, Michael Teng, Homero San Juan-Vergara, Subhra Mohapatra, Shyam Mohapatra

Impact of Chikungunya Virus on Aedes albopictus Females and Possibility of Vertical Transmission Using the Actors of the 2007 Outbreak in Italy

Romeo Bellini, Anna Medici, Mattia Calzolari, Paolo Bonilauri, Francesca Cavrini, Vittorio Sambri, Paola Angelini, Michele Dottori

Skeletal Muscle PGC-1α Is Required for Maintaining an Acute LPS-Induced TNFα Response

Jesper Olesen, Signe Larsson, Ninna Iversen, Simi Yousafzai, Ylva Hellsten, Henriette Pilegaard

Microallopatry Caused Strong Diversification in Buthus scorpions (Scorpiones: Buthidae) in the Atlas Mountains (NW Africa)

Jan C. Habel, Martin Husemann, Thomas Schmitt, Frank E. Zachos, Ann-Christin Honnen, Britt Petersen, Aristeidis Parmakelis, Iasmi Stathi

Platelet-Associated CD40/CD154 Mediates Remote Tissue Damage after Mesenteric Ischemia/Reperfusion Injury

Peter H. Lapchak, Antonis Ioannou, Lakshmi Kannan, Poonam Rani, Jurandir J. Dalle Lucca, George C. Tsokos

Dual Role of Respiratory Syncytial Virus Glycoprotein Fragment as a Mucosal Immunogen and Chemotactic Adjuvant

Sol Kim, Dong-Hyun Joo, Jee-Boong Lee, Byoung-Shik Shim, In Su Cheon, Ji-Eun Jang, Ho-Hyun Song, Kyung-Hyo Kim, Man Ki Song, Jun Chang

HIV Epidemic Appraisals for Assisting in the Design of Effective Prevention Programmes: Shifting the Paradigm Back to Basics

Sharmistha Mishra, Sema K. Sgaier, Laura H. Thompson, Stephen Moses, B. M. Ramesh, Michel Alary, David Wilson, James F. Blanchard

Causes and Correlates of Calf Mortality in Captive Asian Elephants (Elephas maximus)

Khyne U. Mar, Mirkka Lahdenper？, Virpi Lummaa

Automatic Analysis of Composite Physical Signals Using Non-Negative Factorization and Information Criterion

Kenji Watanabe, Akinori Hidaka, Nobuyuki Otsu, Takio Kurita

ROR1 Is Expressed in Human Breast Cancer and Associated with Enhanced Tumor-Cell Growth

Suping Zhang,Liguang Chen,Bing Cui,Han-Yu Chuang,Jianqiang Yu,Jessica Wang-Rodriguez,Li Tang,George Chen,Grzegorz W. Basak,Thomas J. Kipps

Selective Loss of Chemokine Receptor Expression on Leukocytes after Cell Isolation

Juan C. Nieto,Elisabet Cantó,Carlos Zamora,M. Angels Ortiz,Cándido Juárez,Silvia Vidal

Common Genetic Variations in the NALP3 Inflammasome Are Associated with Delayed Apoptosis of Human Neutrophils

Robert Blomgran,Veronika Patcha Brodin,Deepti Verma,Ida Bergstr？m,Peter S？derkvist,Christopher Sj？wall,Per Eriksson,Maria Lerm,Olle Stendahl,Eva S？rndahl

Evidence for the Contribution of the Hemozoin Synthesis Pathway of the Murine Plasmodium yoelii to the Resistance to Artemisinin-Related Drugs

Benoit Witkowski, Joel Lelièvre, Marie-Laure Nicolau-Travers, Xavier Iriart, Patrice Njomnang Soh, Fatima Bousejra-ElGarah, Bernard Meunier, Antoine Berry, Fran？oise Benoit-Vical

Estimating the Burden of Malaria in Senegal: Bayesian Zero-Inflated Binomial Geostatistical Modeling of the MIS 2008 Data

Federica Giardina, Laura Gosoniu, Lassana Konate, Mame Birame Diouf, Robert Perry, Oumar Gaye, Ousmane Faye, Penelope Vounatsou

Leber Congenital Amaurosis Associated with AIPL1: Challenges in Ascribing Disease Causation, Clinical Findings, and Implications for Gene Therapy

Mei Hong Tan, Donna S. Mackay, Jill Cowing, Hoai Viet Tran, Alexander J. Smith, Genevieve A. Wright, Arundhati Dev-Borman, Robert H. Henderson, Phillip Moradi, Isabelle Russell-Eggitt, Robert E. MacLaren, Anthony G. Robson, Michael E. Cheetham, Dorothy A. Thompson, Andrew R. Webster, Michel Michaelides, Robin R. Ali, Anthony T. Moore

Deletion of Porcn in Mice Leads to Multiple Developmental Defects and Models Human Focal Dermal Hypoplasia (Goltz Syndrome)

Wei Liu, Timothy M. Shaver, Alfred Balasa, M. Cecilia Ljungberg, Xiaoling Wang, Shu Wen, Hoang Nguyen, Ignatia B. Van den Veyver

Signatures of T Cells as Correlates of Immunity to Francisella tularensis

Kjell Enesl？tt, Monica Normark, Rafael Bj？rk, Cecilia Rietz, Carl Zingmark, Lawrence A. Wolfraim, Svenja St？ven, Anders Sj？stedt

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