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PLOS ONE

ISSN Print: 1932-6203

ISSN Online:

主页: http://www.plosone.org/

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Renal Function and Risk Factors of Moderate to Severe Chronic Kidney Disease in Golestan Province, Northeast of Iran

Iraj Najafi,Fatemeh Attari,Farhad Islami,Ramin Shakeri,Fatemeh Malekzadeh,Rasool Salahi,Mina Yapan Gharavi,Mostafa Hosseini,Behrooz Broumand,Ali Nobakht Haghighi,Bagher Larijani,Reza Malekzadeh

Standardizing Clinical Trials Workflow Representation in UML for International Site Comparison

Elias Cesar Araujo de Carvalho,Madhav Kishore Jayanti,Adelia Portero Batilana,Andreia M. O. Kozan,Maria J. Rodrigues,Jatin Shah,Marco R. Loures,Sunita Patil,Philip Payne,Ricardo Pietrobon

Phylogenetic and Phyletic Studies of Informational Genes in Genomes Highlight Existence of a 4th Domain of Life Including Giant Viruses

Micka？l Boyer,Mohammed-Amine Madoui,Gregory Gimenez,Bernard La Scola,Didier Raoult

Muscle Physiology Changes Induced by Every Other Day Feeding and Endurance Exercise in Mice: Effects on Physical Performance

Elizabeth Rodríguez-Bies,Sara Santa-Cruz Calvo,ángela Fontán-Lozano,José Pe？a Amaro,Francisco J. Berral de la Rosa,ángel M. Carrión,Plácido Navas,Guillermo López-Lluch

Determinants of Initiation Codon Selection during Translation in Mammalian Cells

Daiki Matsuda,Vincent P. Mauro

Role of Carbonic Anhydrase IV in the Bicarbonate-Mediated Activation of Murine and Human Sperm

Petra M. Wandernoth,Michael Raubuch,Nadja Mannowetz,Holger M. Becker,Joachim W. Deitmer,William S. Sly,Gunther Wennemuth

Targeted Disruption of Ing2 Results in Defective Spermatogenesis and Development of Soft-Tissue Sarcomas

Motonobu Saito,Kensuke Kumamoto,Ana I. Robles,Izumi Horikawa,Bungo Furusato,Shu Okamura,Akiteru Goto,Taro Yamashita,Makoto Nagashima,Tin-Lap Lee,Vanessa J. Baxendale,Owen M. Rennert,Seiichi Takenoshita,Jun Yokota,Isabell A. Sesterhenn,Glenwood E. Trivers,S. Perwez Hussain,Curtis C. Harris

Orally Administered P22 Phage Tailspike Protein Reduces Salmonella Colonization in Chickens: Prospects of a Novel Therapy against Bacterial Infections

Shakeeba Waseh,Pejman Hanifi-Moghaddam,Russell Coleman,Michael Masotti,Shannon Ryan,Mary Foss,Roger MacKenzie,Matthew Henry,Christine M. Szymanski,Jamshid Tanha

Elastin Peptides Signaling Relies on Neuraminidase-1-Dependent Lactosylceramide Generation

Anthony Rusciani,Laurent Duca,Hervé Sartelet,Aurore Chatron-Colliet,Hélène Bobichon,Dominique Ploton,Richard Le Naour,Sébastien Blaise,Laurent Martiny,Laurent Debelle

The Ubiquitin Ligase Ubr2, a Recognition E3 Component of the N-End Rule Pathway, Stabilizes Tex19.1 during Spermatogenesis

Fang Yang,Yong Cheng,Jee Young An,Yong Tae Kwon,Sigrid Eckardt,N. Adrian Leu,K. John McLaughlin,Peijing Jeremy Wang

Imaging Immune Surveillance of Individual Natural Killer Cells Confined in Microwell Arrays

Karolin Guldevall,Bruno Vanherberghen,Thomas Frisk,Johan Hurtig,Athanasia E. Christakou,Otto Manneberg,Sara Lindstr？m,Helene Andersson-Svahn,Martin Wiklund,Bj？rn ？nfelt

Characterisation of PduS, the pdu Metabolosome Corrin Reductase, and Evidence of Substructural Organisation within the Bacterial Microcompartment

Joshua B. Parsons,Andrew D. Lawrence,Kirsty J. McLean,Andrew W. Munro,Stephen E. J. Rigby,Martin J. Warren

Economic Conditions Predict Prevalence of West Nile Virus

Ryan J. Harrigan,Henri A. Thomassen,Wolfgang Buermann,Robert F. Cummings,Matthew E. Kahn,Thomas B. Smith

Evidence for a Transport-Trap Mode of Drosophila melanogaster gurken mRNA Localization

Lan Lan,Shengyin Lin,Sui Zhang,Robert S. Cohen

A Screen for RNA-Binding Proteins in Yeast Indicates Dual Functions for Many Enzymes

Tanja Scherrer,Nitish Mittal,Sarath Chandra Janga,André P. Gerber

Functional Interaction between Acyl-CoA Synthetase 4, Lipooxygenases and Cyclooxygenase-2 in the Aggressive Phenotype of Breast Cancer Cells

Paula M. Maloberti,Alejandra B. Duarte,Ulises D. Orlando,María E. Pasqualini,ángela R. Solano,Carlos López-Otín,Ernesto J. Podestá

Statistical Metamodeling for Revealing Synergistic Antimicrobial Interactions

Chia Hsiang Chen,Vincent Gau,Donna D. Zhang,Joseph C. Liao,Fei-Yue Wang,Pak Kin Wong

Speeded Near Infrared Spectroscopy (NIRS) Response Detection

Xu Cui,Signe Bray,Allan L. Reiss

Idiopathic Male Infertility Is Strongly Associated with Aberrant Promoter Methylation of Methylenetetrahydrofolate Reductase (MTHFR)

Wei Wu,Ouxi Shen,Yufeng Qin,Xiaobing Niu,Chuncheng Lu,Yankai Xia,Ling Song,Shoulin Wang,Xinru Wang

Early Acquisition of Neural Crest Competence During hESCs Neuralization

Carol Lynn Curchoe,Jochen Maurer,Sonja J. McKeown,Giulio Cattarossi,Flavio Cimadamore,Mats Nilbratt,Evan Y. Snyder,Marianne Bronner-Fraser,Alexey V. Terskikh

Activation of Regulatory T Cells during Inflammatory Response Is Not an Exclusive Property of Stem Cells

Jan-Hendrik Gosemann, Joachim F. Kuebler, Michela Pozzobon, Claudia Neunaber, Julia H. K. Hensel, Marco Ghionzoli, Paolo de Coppi, Benno M. Ure, Gesine Holze

Functional and Topological Properties in Hepatocellular Carcinoma Transcriptome

Ignat Drozdov, Jan Bornschein, Thomas Wex, Najl V. Valeyev, Sophia Tsoka, Peter Malfertheiner

Modeling the Impact of Integrating HIV and Outpatient Health Services on Patient Waiting Times in an Urban Health Clinic in Zambia

Sarang Deo, Stephanie M. Topp, Ariel Garcia, Mallory Soldner, Kezban Yagci Sokat, Julien Chipukuma, Chibesa S. Wamulume, Stewart E. Reid, Julie Swann

Competitive Reporter Monitored Amplification (CMA) - Quantification of Molecular Targets by Real Time Monitoring of Competitive Reporter Hybridization

Thomas Ullrich, Eugen Ermantraut, Torsten Schulz, Katrin Steinmetzer

Timeliness of Childhood Vaccinations in Kampala Uganda: A Community-Based Cross-Sectional Study

Juliet N. Babirye, Ingunn M. S. Engebretsen, Frederick Makumbi, Lars T. Fadnes, Henry Wamani, Thorkild Tylleskar, Fred Nuwaha

Restoration of Contralateral Representation in the Mouse Somatosensory Cortex after Crossing Nerve Transfer

Haruyoshi Yamashita, Shanlin Chen, Seiji Komagata, Ryuichi Hishida, Takuji Iwasato, Shigeyoshi Itohara, Takeshi Yagi, Naoto Endo, Minoru Shibata, Katsuei Shibuki

Characterisation of Innate Fungal Recognition in the Lung

Inês Faro-Trindade, Janet A. Willment, Ann M. Kerrigan, Pierre Redelinghuys, Sabelo Hadebe, Delyth M. Reid, Naren Srinivasan, Helen Wainwright, Dirk M. Lang, Chad Steele, Gordon D. Brown

Seroprevalence of Pertussis in the Netherlands: Evidence for Increased Circulation of Bordetella pertussis

Sabine C. de Greeff,Hester E. de Melker,Pieter G. M. van Gageldonk,Joop F. P. Schellekens,Fiona R. M. van der Klis,Liesbeth Mollema,Frits R. Mooi,Guy A. M. Berbers

Exploring Species Limits in Two Closely Related Chinese Oaks

Yan-Fei Zeng,Wan-Jin Liao,Rémy J. Petit,Da-Yong Zhang

Alkalizing Reactions Streamline Cellular Metabolism in Acidogenic Microorganisms

Stefania Arioli,Enzio Ragg,Leonardo Scaglioni,Dimitrios Fessas,Marco Signorelli,Matti Karp,Daniele Daffonchio,Ivano De Noni,Laura Mulas,Marco Oggioni,Simone Guglielmetti,Diego Mora

A New Mouse Model for Marfan Syndrome Presents Phenotypic Variability Associated with the Genetic Background and Overall Levels of Fbn1 Expression

Bruno L. Lima,Enrico J. C. Santos,Gustavo R. Fernandes,Christian Merkel,Marco R. B. Mello,Juliana P. A. Gomes,Marina Soukoyan,Alexandre Kerkis,Silvia M. G. Massironi,José A. Visintin,Lygia V. Pereira

Biased Signaling of the Angiotensin II Type 1 Receptor Can Be Mediated through Distinct Mechanisms

Marie Mi Bonde,Jonas Tind Hansen,Samra Joke Sanni,Stig Hauns？,Steen Gammeltoft,Christina Lyngs？,Jakob Lerche Hansen

High and Increasing Oxa-51 DNA Load Predict Mortality in Acinetobacter baumannii Bacteremia: Implication for Pathogenesis and Evaluation of Therapy

Yu-Chung Chuang,Shan-Chwen Chang,Wei-Kung Wang

Baseline Prediction of Combination Therapy Outcome in Hepatitis C Virus 1b Infected Patients by Discriminant Analysis Using Viral and Host Factors

Verónica Saludes,Maria Alma Bracho,Oliver Valero,Mercè Ardèvol,Ramón Planas,Fernando González-Candelas,Vicente Ausina,Elisa Martró

Metabolomic Profiling of Cellular Responses to Carvedilol Enantiomers in Vascular Smooth Muscle Cells

Mingxuan Wang,Jing Bai,Wei Ning Chen,Chi Bun Ching

Two-Photon Imaging of Calcium in Virally Transfected Striate Cortical Neurons of Behaving Monkey

Barbara Heider,Jason L. Nathanson,Ehud Y. Isacoff,Edward M. Callaway,Ralph M. Siegel

Differential Volatile Signatures from Skin, Naevi and Melanoma: A Novel Approach to Detect a Pathological Process

Tatjana Abaffy,Robert Duncan,Daniel D. Riemer,Olaf Tietje,George Elgart,Clara Milikowski,R. Anthony DeFazio

BK Channels Mediate Cholinergic Inhibition of High Frequency Cochlear Hair Cells

Eric Wersinger,Will J. McLean,Paul A. Fuchs,Sonja J. Pyott

Anti-Tumor Effect in Human Lung Cancer by a Combination Treatment of Novel Histone Deacetylase Inhibitors: SL142 or SL325 and Retinoic Acids

Shaoteng Han,Takuya Fukazawa,Tomoki Yamatsuji,Junji Matsuoka,Hiroyuki Miyachi,Yutaka Maeda,Mary Durbin,Yoshio Naomoto

Lipocalin-7 Is a Matricellular Regulator of Angiogenesis

Leslie J. Brown,Mariam Alawoki,Mary E. Crawford,Tiffany Reida,Allison Sears,Tory Torma,Allan R. Albig

POLD2 and KSP37 (FGFBP2) Correlate Strongly with Histology, Stage and Outcome in Ovarian Carcinomas

Bente Vilming Elgaaen,Kari Bente Foss Haug,Junbai Wang,Ole Kristoffer Olstad,Dario Fortunati,Mathias Onsrud,Anne Cathrine Staff,Torill Sauer,Kaare M. Gautvik

Atlantic Leatherback Migratory Paths and Temporary Residence Areas

Sabrina Fossette,Charlotte Girard,Milagros López-Mendilaharsu,Philip Miller,Andrés Domingo,Daniel Evans,Laurent Kelle,Virginie Plot,Laura Prosdocimi,Sebastian Verhage,Philippe Gaspar,Jean-Yves Georges

First-Borns Carry a Higher Metabolic Risk in Early Adulthood: Evidence from a Prospective Cohort Study

Mario Siervo,Bernardo L. Horta,Blossom C. M. Stephan,Cesar G. Victora,Jonathan C. K. Wells

TLR4 Inhibits Mesenchymal Stem Cell (MSC) STAT3 Activation and Thereby Exerts Deleterious Effects on MSC–Mediated Cardioprotection

Yue Wang,Aaron M. Abarbanell,Jeremy L. Herrmann,Brent R. Weil,Mariuxi C. Manukyan,Jeffrey A. Poynter,Daniel R. Meldrum

Suppression of Hypoxia-Inducible Factor 1α (HIF-1α) by Tirapazamine Is Dependent on eIF2α Phosphorylation Rather Than the mTORC1/4E-BP1 Pathway

Jun Zhang,Ji Cao,Qinjie Weng,Rui Wu,Yan Yan,Hui Jing,Hong Zhu,Qiaojun He,Bo Yang

Nanoparticulate Transport of Oximes over an In Vitro Blood-Brain Barrier Model

Sylvia Wagner,Jürgen Kufleitner,Anja Zensi,Miriam Dadparvar,Sascha Wien,Judith Bungert,Tikva Vogel,Franz Worek,J？rg Kreuter,Hagen von Briesen

Transcriptional Analysis Implicates Endoplasmic Reticulum Stress in Bovine Spongiform Encephalopathy

Yue Tang,Wei Xiang,Linda Terry,Hans A. Kretzschmar,Otto Windl

The ERAD Inhibitor Eeyarestatin I Is a Bifunctional Compound with a Membrane-Binding Domain and a p97/VCP Inhibitory Group

Qiuyan Wang,Bidhan A. Shinkre,Jin-gu Lee,Marc A. Weniger,Yanfen Liu,Weiping Chen,Adrian Wiestner,William C. Trenkle,Yihong Ye

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