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PLOS ONE

ISSN Print: 1932-6203

ISSN Online:

主页: http://www.plosone.org/

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The reg4 Gene, Amplified in the Early Stages of Pancreatic Cancer Development, Is a Promising Therapeutic Target

Aude Legoffic,Ezequiel Calvo,Carla Cano,Emma Folch-Puy,Marc Barthet,Jean Robert Delpero,Montse Ferrés-Masó,Jean Charles Dagorn,Daniel Closa,Juan Iovanna

Up-Regulation of Hepatitis C Virus Replication and Production by Inhibition of MEK/ERK Signaling

Jean Ndjomou,In-woo Park,Ying Liu,Lindsey D. Mayo,Johnny J. He

Unravelling the Relationship between Animal Growth and Immune Response during Micro-Parasitic Infections

Andrea B. Doeschl-Wilson,Will Brindle,Gerry Emmans,Ilias Kyriazakis

Caspase-Dependent Inhibition of Mousepox Replication by gzmB

Julián Pardo,Eva Ma Gálvez,Aulikki Koskinen,Markus M. Simon,Mario Lobigs,Matthias Regner,Arno Müllbacher

Influenza A Gradual and Epochal Evolution: Insights from Simple Models

Sébastien Ballesteros,Elisabeta Vergu,Bernard Cazelles

Cross-Talk between Signaling Pathways Can Generate Robust Oscillations in Calcium and cAMP

Fernando Siso-Nadal,Jeffrey J. Fox,Stéphane A. Laporte,Terence E. Hébert,Peter S. Swain

New Episodic Learning Interferes with the Reconsolidation of Autobiographical Memories

Lars Schwabe,Oliver T. Wolf

Crystal Structure of the PIM2 Kinase in Complex with an Organoruthenium Inhibitor

Alex N. Bullock,Santina Russo,Ann Amos,Nicholas Pagano,Howard Bregman,Judit é. Debreczeni,Wen Hwa Lee,Frank von Delft,Eric Meggers,Stefan Knapp

DAZL Relieves miRNA-Mediated Repression of Germline mRNAs by Controlling Poly(A) Tail Length in Zebrafish

Yasuaki Takeda,Yuichiro Mishima,Toshinobu Fujiwara,Hiroshi Sakamoto,Kunio Inoue

SGC - Structural Biology and Human Health: A New Approach to Publishing Structural Biology Results

Wen Hwa Lee,Julián Atienza-Herrero,Ruben Abagyan,Brian D. Marsden

Crystal Structure of the N-Acetylmannosamine Kinase Domain of GNE

Yufeng Tong,Wolfram Tempel,Lyudmila Nedyalkova,Farrell MacKenzie,Hee-Won Park

The Pentameric Vertex Proteins Are Necessary for the Icosahedral Carboxysome Shell to Function as a CO2 Leakage Barrier

Fei Cai,Balaraj B. Menon,Gordon C. Cannon,Kenneth J. Curry,Jessup M. Shively,Sabine Heinhorst

Evidence for Repeated Independent Evolution of Migration in the Largest Family of Bats

Isabelle-Anne Bisson,Kamran Safi,Richard A. Holland

Variation at GRN 3′-UTR rs5848 Is Not Associated with a Risk of Frontotemporal Lobar Degeneration in Dutch Population

Javier Simón-Sánchez,Harro Seelaar,Zoltán Bochdanovits,Dorly J. H. Deeg,John C. van Swieten,Peter Heutink

Converting Redox Signaling to Apoptotic Activities by Stress-Responsive Regulators HSF1 and NRF2 in Fenretinide Treated Cancer Cells

Kankan Wang,Hai Fang,Dakai Xiao,Xuehua Zhu,Miaomiao He,Xiaoling Pan,Jiantao Shi,Hui Zhang,Xiaohong Jia,Yanzhi Du,Ji Zhang

Bili Inhibits Wnt/β-Catenin Signaling by Regulating the Recruitment of Axin to LRP6

Lorna S. Kategaya,Binita Changkakoty,Travis Biechele,William H. Conrad,Ajamete Kaykas,Ramanuj DasGupta,Randall T. Moon

Mental Rotation of Faces in Healthy Aging and Alzheimer's Disease

Cassandra A. Adduri,Jonathan J. Marotta

Evidence for X-Chromosomal Schizophrenia Associated with microRNA Alterations

Jinong Feng,Guihua Sun,Jin Yan,Katie Noltner,Wenyan Li,Carolyn H. Buzin,Jeff Longmate,Leonard L. Heston,John Rossi,Steve S. Sommer

Competitive Asymmetries in the Use of Supplementary Food by the Endangered Iberian Lynx (Lynx pardinus)

José V. López-Bao,Alejandro Rodríguez,Francisco Palomares

Rab11 Helps Maintain Apical Crumbs and Adherens Junctions in the Drosophila Embryonic Ectoderm

Jeremiah F. Roeth,Jessica K. Sawyer,Daniel A. Wilner,Mark Peifer

PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 Are Associated with Type 2 Diabetes in a Chinese Population

Cheng Hu,Rong Zhang,Congrong Wang,Jie Wang,Xiaojing Ma,Jingyi Lu,Wen Qin,Xuhong Hou,Chen Wang,Yuqian Bao,Kunsan Xiang,Weiping Jia

Cutaneous Chronic Graft-Versus-Host Disease Does Not Have the Abnormal Endothelial Phenotype or Vascular Rarefaction Characteristic of Systemic Sclerosis

Jo Nadine Fleming,Howard M. Shulman,Richard A. Nash,Pamela Y. Johnson,Thomas N. Wight,Allen Gown,Stephen M. Schwartz

Staphylococcal Enterotoxin A Induces Small Clusters of HLA-DR1 on B Cells

Kedar Narayan,Edward M. Perkins,Gavin E. Murphy,Sarat K. Dalai,Michael Edidin,Sriram Subramaniam,Scheherazade Sadegh-Nasseri

Identification of Global Transcriptional Dynamics

Eric H. Yang,Richard R. Almon,Debra C. DuBois,Willian J. Jusko,Ioannis P. Androulakis

Rubber Hand Illusion under Delayed Visual Feedback

Sotaro Shimada,Kensuke Fukuda,Kazuo Hiraki

The Temporal Dynamics of Voluntary Emotion Regulation

Henrik Walter,Alexander von Kalckreuth,Dina Schardt,Achim Stephan,Thomas Goschke,Susanne Erk

The Repertoire of Heterotrimeric G Proteins and RGS Proteins in Ciona intestinalis

R. Prasobh,Narayanan Manoj

High Resolution MEMS Accelerometers to Estimate VO2 and Compare Running Mechanics between Highly Trained Inter-Collegiate and Untrained Runners

Stephen J. McGregor,Michael A. Busa,James A. Yaggie,Erik M. Bollt

CFH, C3 and ARMS2 Are Significant Risk Loci for Susceptibility but Not for Disease Progression of Geographic Atrophy Due to AMD

Hendrik P. N. Scholl,Monika Fleckenstein,Lars G. Fritsche,Steffen Schmitz-Valckenberg,Arno G？bel,Christine Adrion,Christine Herold,Claudia N. Keilhauer,Friederike Mackensen,Andreas M？？ner,Daniel Pauleikhoff,Andreas W. A. Weinberger,Ulrich Mansmann,Frank G. Holz,Tim Becker,Bernhard H. F. Weber

Restoration of Podocyte Structure and Improvement of Chronic Renal Disease in Transgenic Mice Overexpressing Renin

Anne-Cécile Huby,Maria-Pia Rastaldi,Kathleen Caron,Oliver Smithies,Jean-Claude Dussaule,Christos Chatziantoniou

Phagocytosis of Streptococcus pyogenes by All-Trans Retinoic Acid-Differentiated HL-60 Cells: Roles of Azurophilic Granules and NADPH Oxidase

Pontus Nordenfelt,Susanne Bauer,Per L？nnbro,Hans Tapper

Circadian Modulation of Gene Expression, but not Glutamate Uptake, in Mouse and Rat Cortical Astrocytes

Christian Beaulé,Adrienne Swanstrom,María Juliana Leone,Erik D. Herzog

P110 and P140 Cytadherence-Related Proteins Are Negative Effectors of Terminal Organelle Duplication in Mycoplasma genitalium

Oscar Q. Pich,Raul Burgos,Enrique Querol,Jaume Pi？ol

Chimpanzees Help Each Other upon Request

Shinya Yamamoto,Tatyana Humle,Masayuki Tanaka

Structural and Functional Similarity between the Bacterial Type III Secretion System Needle Protein PrgI and the Eukaryotic Apoptosis Bcl-2 Proteins

Matthew D. Shortridge,Robert Powers

Heterosis Is Prevalent for Multiple Traits in Diverse Maize Germplasm

Sherry A. Flint-Garcia,Edward S. Buckler,Peter Tiffin,Elhan Ersoz,Nathan M. Springer

The Perfect Family: Decision Making in Biparental Care

Erol Ak？ay,Joan Roughgarden

Calprotectin — A Novel Marker of Obesity

Ole Hartvig Mortensen,Anders Rinnov Nielsen,Christian Erikstrup,Peter Plomgaard,Christian Philip Fischer,Rikke Krogh-Madsen,Birgitte Lindegaard,Anne Marie Petersen,Sarah Taudorf,Bente Klarlund Pedersen

Short Telomeres in Hatchling Snakes: Erythrocyte Telomere Dynamics and Longevity in Tropical Pythons

Beata Ujvari,Thomas Madsen

Identification of Markers that Distinguish Monocyte-Derived Fibrocytes from Monocytes, Macrophages, and Fibroblasts

Darrell Pilling,Ted Fan,Donna Huang,Bhavika Kaul,Richard H. Gomer

Duration, Pattern of Breastfeeding and Postnatal Transmission of HIV: Pooled Analysis of Individual Data from West and South African Cohorts

Renaud Becquet,Ruth Bland,Valériane Leroy,Nigel C. Rollins,Didier K. Ekouevi,Anna Coutsoudis,Fran？ois Dabis,Hoosen M. Coovadia,Roger Salamon,Marie-Louise Newell

New Antibiotic Molecules: Bypassing the Membrane Barrier of Gram Negative Bacteria Increases the Activity of Peptide Deformylase Inhibitors

Laurent Mamelli,Sylvain Petit,Jacqueline Chevalier,Carmela Giglione,Aurélie Lieutaud,Thierry Meinnel,Isabelle Artaud,Jean-Marie Pagès

Social Structure Predicts Genital Morphology in African Mole-Rats

Marianne L. Seney,Diane A. Kelly,Bruce D. Goldman,Radim ？umbera,Nancy G. Forger

Using Dynamic Stochastic Modelling to Estimate Population Risk Factors in Infectious Disease: The Example of FIV in 15 Cat Populations

David Fouchet,Guillaume Leblanc,Frank Sauvage,Micheline Guiserix,Hervé Poulet,Dominique Pontier

Ecological Equivalence: A Realistic Assumption for Niche Theory as a Testable Alternative to Neutral Theory

C. Patrick Doncaster

A Novel Adeno-Associated Viral Variant for Efficient and Selective Intravitreal Transduction of Rat Müller Cells

Ryan R. Klimczak,James T. Koerber,Deniz Dalkara,John G. Flannery,David V. Schaffer

Intragenic and Extragenic Suppressors of Temperature Sensitive Mutations in the Replication Initiation Genes dnaD and dnaB of Bacillus subtilis

Megan E. Rokop,Alan D. Grossman

Climatic Changes Lead to Declining Winter Chill for Fruit and Nut Trees in California during 1950–2099

Eike Luedeling,Minghua Zhang,Evan H. Girvetz

Cytokine-Based Log-Scale Expansion of Functional Murine Dendritic Cells

Yui Harada,Yasuji Ueda,Hiroaki Kinoh,Atsushi Komaru,Terumi Fuji-Ogawa,Aki Furuya,Akihiro Iida,Mamoru Hasegawa,Tomohiko Ichikawa,Yoshikazu Yonemitsu

Characterization of Chromosomal Instability in Murine Colitis-Associated Colorectal Cancer

Marco Gerling,Rainer Glauben,Jens K. Habermann,Anja A. Kühl,Christoph Loddenkemper,Hans-Anton Lehr,Martin Zeitz,Britta Siegmund

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