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ISSN: 2333-9721
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G protein α subunit suppresses sporangium formation through a serine/threonine protein kinase in Phytophthora sojae

Baiyu Zhang,Francine Govers,Min Qiu,Mingrun Xuan,Wenwu Ye,Xiaobo Zheng,Xin Zhang,Yaning Li,Yuanchao Wang

USP44 positively regulates innate immune response to DNA viruses through deubiquitinating MITA

Bo-Wei Liao,Dong-Peng Wang,Hong-Yan Zhang,Wei-Wei Luo,Yan Yang,Yan-Yi Wang,Yong Ran,Zhi-Sheng Xu

Structural basis of Fusarium myosin I inhibition by phenamacril

Feng Zhang,H. Eric Xu,Joseph S. Brunzelle,Karsten Melcher,Mingguo Zhou,X. Edward Zhou,Xiaoman Cao,Yuanping Gong,Yuanye Zhu,Yuxin Zhou

Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition

Celia C. LaBranche,Dallas R. Brown,David C. Montefiori,David J. Venzon,Deborah H. Fuller,Fredrik Barren？s,Genoveffa Franchini,Georgia D. Tomaras,Giacomo Gorini,Hung V. Trinh,Isabela Silva de Castro,Jean Chang,Luca Schifanella,Lynn Law,Mangala Rao,Massimiliano Bissa,Melvin N. Doster,Michael Agy,Michael Gale Jr.,Mohammad Arif Rahman,Monica Vaccari,Namal P. M. Liyanage,Rafick P. Sekaly,Ranajit Pal,Richard Green,Robert E. Palermo,Robyn Washington-Parks,Sampa Santra,Shari N. Gordon,Slim Fourati,Veronica Galli,Xiaoying Shen

High crossreactivity of human T cell responses between Lassa virus lineages

Augustine Goba,Beatrice Cubitt,Brian C. Ware,Brian M. Sullivan,Christian Happi,Donald S. Grant,Dylan Kotliar,Ephraim Ogbaini-Emovon,Ikponmwosa Odia,Jessica N. Hartnett,John Demby Sandi,John S. Schieffelin,Juan Carlos de la Torre,Karthik Gangavarapu,Kristian G. Andersen,Lansana Kanneh,Luis Branco,Mambu Momoh,Michael B. A. Oldstone,Nhi Ngo,Onikepe Folarin,Pardis C. Sabeti,Peter O. Okokhere,Philomena Eromon,Refugio Robles-Sikisaka,Robert F. Garry,Saori Sakabe,Selma D. Garcia,Sylvanus Okogbenin

Comprehensive analysis of iron utilization by Mycobacterium tuberculosis

Elliot J. Lefkowitz,Lei Zhang,Michael Niederweis,R. Curtis Hendrickson,Thomas R. Ioerger,Virginia Meikle

Evolving moldy murderers: Aspergillus section Fumigati as a model for studying the repeated evolution of fungal pathogenicity

Antonis Rokas,Gustavo H. Goldman,Jacob L. Steenwyk,Matthew E. Mead,Nicholas H. Oberlies

Signatures of oral microbiome in HIV-infected individuals with oral Kaposi's sarcoma and cell-associated KSHV DNA

Denise Whitby,Marion Gruffaz,Nazzarena Labo,Priscila Gon？alves,Ramya Ramaswami,Robert Yarchoan,Shou-Jiang Gao,Thomas S. Uldrick,Tinghe Zhang,Vickie Marshall,Yufei Huang

Agricultural and geographic factors shaped the North American 2015 highly pathogenic avian influenza H5N2 outbreak

David E. Swayne,Dong-Hun Lee,Joseph T. Hicks,Justin Bahl,Mia Kim Torchetti,Venkata R. Duvvuri

Viral infection triggers interferon-induced expulsion of live Cryptococcus neoformans by macrophages

Dalan Bailey,David Stirling,Leanne M. Taylor-Smith,Lucy C. K. Bell,Mahdad Noursadeghi,Paula I. Seoane,Robin C. May

Broad dengue neutralization in mosquitoes expressing an engineered antibody

Anna Buchman,Chun-Hong Chen,Hsin-Wei Wang,Hsing-Han Li,Igor Antoshechkin,James E. Crowe Jr.,Jean-Bernard Duchemin,Melissa J. Klein,Ming Li,Omar S. Akbari,Prasad N. Paradkar,Stephanie Gamez

The B-cell inhibitory receptor CD22 is a major factor in host resistance to Streptococcus pneumoniae infection

Alan Bénard,Carolin Brandl,Georg F. Weber,Giuseppe Ercoli,Hannah Fahnenstiel,Jennifer Müller-Winkler,Lars Nitschke,Paul Denny,Peter W. Andrew,Vitor E. Fernandes

Multiple weak interactions between BvgA~P and ptx promoter DNA strongly activate transcription of pertussis toxin genes in Bordetella pertussis

Philip E. Boucher,Qing Chen,Scott Stibitz

Platelets are critical for survival and tissue integrity during murine pulmonary Aspergillus fumigatus infection

Benjamin Y. Tischler,Nicholas L. Tosini,Robert A. Cramer,Tobias M. Hohl

Toxoplasma gondii requires its plant-like heme biosynthesis pathway for infection

Amy Bergmann,Carly Dameron,Daniel C. Whitehead,Iqbal Hamza,Katherine Floyd,Kerrick C. Rees,L. Brock Thornton,Melanie Key,Zhicheng Dou

The C. elegans CHP1 homolog, pbo-1, functions in innate immunity by regulating the pH of the intestinal lumen

Aaron M. Bender,Blake R. Peterson,Brian D. Ackley,Josephine R. Chandler,Patrick Lansdon,Saida Benomar

A shear stress micromodel of urinary tract infection by the Escherichia coli producing Dr adhesin

Anna Skwarska,Beata Zalewska-Pi？tek,Bogdan Nowicki,Marcin Olszewski,Mi？osz Wieczór,Piotr Bru？dziak,Rafa？ Pi？tek,Stella Nowicki,S？awomir B？oński,Tomasz Lipniacki

Epigenetic factor siRNA screen during primary KSHV infection identifies novel host restriction factors for the lytic cycle of KSHV

Bernadett Papp,Gavin Golas,Katherine Glickman,Lauren Roberts,Luke Todd Fischer,Nenavath Gopal Naik,Thomas Hong Nguyen,Zsolt Toth

Human cytomegalovirus long noncoding RNA4.9 regulates viral DNA replication

Adi Ezra,Aharon Nachshon,Andrew J. Davison,Betty Lau,Erez Eliyahu,Julie Tai-Schmiedel,Karen Kerr,Michal Schwartz,Nicolás Suárez,Noam Stern-Ginossar,Sharon Karniely

A refined model of how Yersinia pestis produces a transmissible infection in its flea vector

Amélie Dewitte,Ana？s Hujeux,Elizabeth Pradel,Florent Sebbane,Fran？ois Pierre,Isabelle Ricard,Nicolas Barois,Sébastien Bontemps-Gallo,Typhanie Bouvenot

Cofactor and glycosylation preferences for in vitro prion conversion are predominantly determined by strain conformation

Cassandra M. Burke,Daniel J. Walsh,Kenneth M. K. Mark,Koren A. Nishina,Michele A. Di Bari,Nathan R. Deleault,Surachai Supattapone,Umberto Agrimi

Dynamic interactions within the host-associated microbiota cause tumor formation in the basal metazoan Hydra

Alexander Klimovich,Benedikt Mortzfeld,Jan Taubenheim,Kai Rathje,Marc P. Hoeppner,Thomas C. G. Bosch

Distinct epigenomic and transcriptomic modifications associated with Wolbachia-mediated asexuality

Amelia R. I. Lindsey,John H. Werren,Paramita Chatterjee,Richard Stouthamer,Soojin V. Yi,Xin Wu

Latency reversal agents modulate HIV antigen processing and presentation to CD8 T cells

Jishnu Das,Julie Boucau,Neelambari Joshi,Sylvie Le Gall

Gut microbiota promotes host resistance to low-temperature stress by stimulating its arginine and proline metabolism pathway in adult Bactrocera dorsalis

Hongyu Zhang,Muhammad Fahim Raza,Shuai Bai,Umar Anwar Awan,Weiwei Zheng,Yichen Wang,Zhaohui Cai,Zhenyu Zhang,Zhichao Yao

PARP1-cGAS-NF-κB pathway of proinflammatory macrophage activation by extracellular vesicles released during Trypanosoma cruzi infection and Chagas disease

Nisha Jain Garg,Subhadip Choudhuri

Loss of tetherin antagonism by Nef impairs SIV replication during acute infection of rhesus macaques

Aidin Tavakoli-Tameh,David T. Evans,Hajime Uno,Jeffrey D. Lifson,Katie Zarbock,Kristin Crosno,Sanath Kumar Janaka,Saverio Capuano 3rd,Shelby O’Connor

Role of MPK4 in pathogen-associated molecular pattern-triggered alternative splicing in Arabidopsis

Heribert Hirt,Jeremie Bazin,Kiruthiga Mariappan,Martin Crespi,Ronny Voelz,Thomas Blein,Yunhe Jiang

Chemical intervention of influenza virus mRNA nuclear export

Adolfo García-Sastre,Adwait A. Sathe,Alexander White,Amir Mor,Beatriz M. A. Fontoura,Bruce Posner,Chao Xing,Hanspeter Niederstrasser,Jerry W. Shay,Joseph Ready,Juan Wang,Jue Liang,Ke Zhang,Kris White,Matthew Esparza,Ramanavelan Sakthivel,Raquel Mu？oz-Moreno,Sei Sho,Shengyan Gao

Multiple Wolbachia strains provide comparative levels of protection against dengue virus infection in Aedes aegypti

Bridget Wills,Cameron P. Simmons,Duong Thi Hue Kien,Heather A. Flores,Huynh Le Anh Huy,Huynh Thi Le Duyen,Huynh Thi Thuy Van,Huynh Thi Xuan Trang,Jyotika Taneja de Bruyne,Lauren B. Carrington,Le Thi Dui,Nguyen Thanh Phong,Nguyen Thi Giang,Nguyen Thi Van Thuy,Nguyen Van Vinh Chau,Scott L. O’Neill,Tanya B. O’Donnell,Tran Thuy Vi,Vo Thi Long,Vu Tuyet Nhu

Variations in microbiota composition of laboratory mice influence Citrobacter rodentium infection via variable short-chain fatty acid production

Dirk Schlüter,Eric J. C. Gálvez,Karsten Hiller,Kerstin Schmidt-Hohagen,Lisa Osbelt,Madita Schr？ter,Marina C. Pils,Meina Neumann-Schaal,Nathiana Smit,Petra Dersch,Sabrina Mühlen,Sophie Thiemann,Till Robin Lesker,Till Strowig

In silico design of a T-cell epitope vaccine candidate for parasitic helminth infection

Andrew Brass,Ayat Zawawi,Hannah Smith,Iris Mair,Jeremy P. Derrick,Kathryn J. Else,Munirah H. Albaqshi,Murtala Jibril,Ruth Forman

Mycobacterium abscessus infection leads to enhanced production of type 1 interferon and NLRP3 inflammasome activation in murine macrophages via mitochondrial oxidative stress

Bo-Ram Kim,Bum-Joon Kim,Byoung-Jun Kim,Yoon-Hoh Kook

Surfing motility is a complex adaptation dependent on the stringent stress response in Pseudomonas aeruginosa LESB58

Caleb Ritchie,Daniel Pletzer,Evelyn Sun,Heidi Wolfmeier,Lauren Wilkinson,Leo T. Liu,Michael J. Trimble,Robert E. W. Hancock,Travis M. Blimkie

Baloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmission

Aeron C. Hurt,Aoe-Ishikawa Yuki,Barry Clinch,Daniel H. Goldhill,Edin J. Mifsud,Elke Zwanziger,Jie Zhou,Kaoru Baba,Kenji Sato,Klaus Kuhlbusch,Leo Yi Yang Lee,Neil Collinson,Paulina Koszalka,Rebecca Frise,Steffen Wildum,Takahiro Noda,Takao Shishido,Takeki Uehara,Wendy S. Barclay,Yoshinori Ando

When a Palearctic bacterium meets a Nearctic insect vector: Genetic and ecological insights into the emergence of the grapevine Flavescence dorée epidemics in Europe

Alberto Materazzi,Barbara Jarausch,Bernard Bergey,Delphine Desqué,Dima Khalil,Elisa Angelini,Friederike Lang,Ibolya Ember,Ivo To？evski,Jean-Luc Danet,Jelena Jovi？,Laure Beven,Luisa Filippin,Maria K？lber,Marie-Pierre Dubrana-Ourabah,Michael Maixner,Michele Della Bartola,Nathalie Arricau-Bouvery,Oliver Krsti？,Pascal Salar,Slobodan Krnjajic,Sybille Duret,Sylvie Malembic-Maher,Xavier Foissac,Zoltan Acs

Cervicovaginal microbiome and natural history of HPV in a longitudinal study

Ana Gradissimo,Carolina Porras,Christine P. Zolnik,Costa Rica HPV Vaccine Trial (CVT) Group,Mahboobeh Safaeian,Mark Schiffman,Mykhaylo Usyk,Paula Gonzalez,Philip E. Castle,Robert D. Burk,Rolando Herrero

Killer cell proteases can target viral immediate-early proteins to control human cytomegalovirus infection in a noncytotoxic manner

Adriana Svrlanska,Astrid Hendriks,Bernadet Blijenberg,Ian J. Groves,Jan Meeldijk,Karlijn J. W. M. van Boxtel,Liling Shan,Mark R. Wills,Martin Potts,Niels Bovenschen,Sara P. H. van den Berg,Shuang Li,Thomas Stamminger

Transcytosis subversion by M cell-to-enterocyte spread promotes Shigella flexneri and Listeria monocytogenes intracellular bacterial dissemination

Camille Rey,Caroline Proux,Hugo Varet,Jean-Yves Coppée,Jost Enninga,Patricia Latour-Lambert,Rachel Legendre,Yuen-Yan Chang

Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy

Abby Oehler,Amanda L. Woerman,Daniel A. Mordes,Jisoo Lee,Sabeen A. Kazmi,Smita Patel,Stanley B. Prusiner,Steven H. Olson

Natural killer cells expanded in vivo or ex vivo with IL-15 overcomes the inherent susceptibility of CAST mice to lethal infection with orthopoxviruses

Bernard Moss,Jeffrey L. Americo,Patricia L. Earl

“Submergence” of Western equine encephalitis virus: Evidence of positive selection argues against genetic drift and fitness reductions

Aaron C. Brault,Aaron L. Miller,Daniel A. Hartman,Jing Huang,Nicholas A. Bergren,Richard A. Bowen,Robert L. Seymour,Scott C. Weaver,Shannan L. Rossi,Sherry Haller

Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13

Audrey Crane,Audrey R. Odom John,Barbara H. Stokes,David A. Fidock,Gavreel F. Kalantarov,Ilya N. Trakht,Judith Straimer,Katja Becker,Kim C. Heimsch,Marcus C. S. Lee,Michal Kuderjavy,Nina F. Gn？dig,Rachel L. Edwards,Sachel Mok

Zika virus infects pericytes in the choroid plexus and enters the central nervous system through the blood-cerebrospinal fluid barrier

Brian Alejandro,Dong-Hoon Chung,Eyas M. Hattab,Hiroshi Ishikawa,Horst Schroten,Jihye Kim,Joshua Joiner,Michal Hetman

A conformation-based intra-molecular initiation factor identified in the flavivirus RNA-dependent RNA polymerase

Bo Zhang,Guoliang Lu,Han-Qing Ye,Jiqin Wu,Peng Gong,Qiu-Yan Zhang

The hallmarks of COVID-19 disease

Daolin Tang,Paul Comish,Rui Kang

The intergenic small non-coding RNA ittA is required for optimal infectivity and tissue tropism in Borrelia burgdorferi

Beau Wager,Diana N. Medina-Pérez,Erin Troy,Jenny A. Hyde,Jon T. Skare,Lihui Gao,Linden Hu,Meghan Lybecker,Steven J. Norris,Tao Lin

Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease

Arthur S. Kim,James C. Slaughter,James. E. Crowe Jr,Julie M. Fox,Laura A. Powell,Mahsa Majedi,Michael S. Diamond,Nurgun Kose,Robert H. Carnahan,Robin Bombardi,Thomas E. Morrison

Salmonella Typhimurium discreet-invasion of the murine gut absorptive epithelium

Anna A. Müller-Hauser,Bidong D. Nguyen,Desirée B？ck,Francesco Bosia,Manfred Rohde,Maria Letizia Di Martino,Markus Furter,Martin Pilhofer,Mikael E. Sellin,Pilar Samperio Ventayol,Sabrina Deuring,Saskia Kreibich,Stefan A. Fattinger,Viktor Ek,Wolf-Dietrich Hardt

Characterizing Emerging Canine H3 Influenza Viruses

Adolfo García-Sastre,Aitor Nogales,Andrew Pekosz,Angela Danner,Anice C. Lowen,Ashley L. Fink,Benjamin L. Miller,Bindumadhav M. Marathe,Brandi Livingston,Brian R. Wasik,Bridgett Sharp,Carole Henry,Charles J. Russell,Cheryl A. Jones,Christopher S. Anderson,Colin R. Parrish,Daniel R. Perez,David A. Steinhauer,David Burke,David J. Topham,David Pattinson,Derek J. Smith,Elena A. Govorkova,Farah el Najjar,Gabriele Neumann,Gavin Smith,Gongxun Zhong,Guohua Yang,Guojun Wang,Hanyuan Zhang,Hui Tao,Huihui Kong,Ian E. H. Voorhees,Jasmina M. Luczo,Jeanne Holden-Wiltse,John J. Treanor,John Steel,Juan Carlos Dib,Kaori Sakamoto,Karlie Woodard,Katherine J. Fenstermacher,Kathryn Shaw-Saliba,Kuan-Fu Chen,Laura Rodriguez,Lauren Byrd-Leotis,Lauren Sauer,Lucas M. Ferreri,Luis Martinez-Sobrido,M. C. W. Chan,Malik Peiris,Mark Y. Sangster,Marta L. DeDiego,Masato Hatta,Mathilde Richard,Melissa B. Uccellini,Mitra K. Lewis,Nicholas Wohlgemuth,Pamela Freiden,Patrick C. Wilson,Paul G. Thomas,Philippe N. Q. Pascua,Phuong Nguyen,Pilar Blanco-Lobo,R. A. P. M. Perera,Richard D. Cummings,Richard E. Rothman,Richard J. Webby,Ron Fouchier,Sabra L. Klein,Sander Herfst,Sanjukta Bandyopadhyay,Scott Krauss,Sean Cherry,Shamika Danzy,Shiho Chiba,Shufang Fan,Stacey Schultz-Cherry,Stephen M. Tompkins,Subrata Barman,Theresa Fitzgerald,Victoria Meliopoulos,Yao-Tsun Li,Yoshihiro Kawaoka,Zhen-Ying Liu

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