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OALib Journal期刊
ISSN: 2333-9721
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主页: https://journals.plos.org/ploscompbiol/

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Mathematical Modeling of Bacterial Kinetics to Predict the Impact of Antibiotic Colonic Exposure and Treatment Duration on the Amount of Resistant Enterobacteria Excreted

Antoine Andremont,Elisabeth Chachaty,France Mentré,Jean de Gunzburg,Jeremie Guedj,Thu Thuy Nguyen

Pupil-Linked Arousal Determines Variability in Perceptual Decision Making

Joachim Vandekerckhove,Peter R. Murphy,Sander Nieuwenhuis

Identifying Cell Types from Spatially Referenced Single-Cell Expression Datasets

Jean-Baptiste Pettit,John Marioni,Kaia Achim,Lamiae Azizi,Raju Tomer,Sylvia Richardson

A Coarse-Grained Elastic Network Atom Contact Model and Its Use in the Simulation of Protein Dynamics and the Prediction of the Effect of Mutations

Rafael J. Najmanovich,Vincent Frappier

Systematic Evaluation of Methods for Integration of Transcriptomic Data into Constraint-Based Models of Metabolism

Daniel Machado,Markus Herrg？rd

HapTree: A Novel Bayesian Framework for Single Individual Polyplotyping Using NGS Data

Bonnie Berger,Deniz Yorukoglu,Emily Berger,Jian Peng

CCAST: A Model-Based Gating Strategy to Isolate Homogeneous Subpopulations in a Heterogeneous Population of Single Cells

Benedict Anchang,Mary T. Do,Sylvia K. Plevritis,Xi Zhao

Investigation of Inflammation and Tissue Patterning in the Gut Using a Spatially Explicit General-Purpose Model of Enteric Tissue (SEGMEnT)

Chase Cockrell,Gary An,Scott Christley

Correction of Distortion in Flattened Representations of the Cortical Surface Allows Prediction of V1-V3 Functional Organization from Anatomy

David H. Brainard,Geoffrey K. Aguirre,Noah C. Benson,Omar H. Butt

From Spontaneous Motor Activity to Coordinated Behaviour: A Developmental Model

Arjun Bharadwaj,Fumiya Iida,Hugo Gravato Marques

CeleST: Computer Vision Software for Quantitative Analysis of C. elegans Swim Behavior Reveals Novel Features of Locomotion

Carolina Ibá？ez-Ventoso,Christophe Restif,Dimitris Metaxas,Mehul M. Vora,Monica Driscoll,Suzhen Guo

PolyUbiquitin Chain Linkage Topology Selects the Functions from the Underlying Binding Landscape

Chun Tang,Erkang Wang,Jin Wang,Yong Wang

ODE Constrained Mixture Modelling: A Method for Unraveling Subpopulation Structures and Dynamics

Christine Hasenauer,Fabian J. Theis,Jan Hasenauer,Tim Hucho

BiP Clustering Facilitates Protein Folding in the Endoplasmic Reticulum

Anne S. Robinson,Carissa Young,Linda Petzold,Marc Griesemer

Chemical, Target, and Bioactive Properties of Allosteric Modulation

Anna Gaulton,Gerard J. P. van Westen,John P. Overington

Optimal Schedules of Light Exposure for Rapidly Correcting Circadian Misalignment

Daniel B. Forger,Kirill Serkh

Long Non-Coding RNA and Alternative Splicing Modulations in Parkinson's Leukocytes Identified by RNA Sequencing

Alessandro Guffanti,Alon Simchovitz,Hagai Bergman,Hermona Soreq,Lilach Soreq,Nathan Salomonis,Zvi Israel

OpenCyto: An Open Source Infrastructure for Scalable, Robust, Reproducible, and Automated, End-to-End Flow Cytometry Data Analysis

Evan W. Newell,Greg Finak,Jacob Frelinger,John Ramey,Mark M. Davis,Raphael Gottardo,Spyros A. Kalams,Stephen C. De Rosa,Wenxin Jiang

Modeling Mutual Exclusivity of Cancer Mutations

Ewa Szczurek,Niko Beerenwinkel

The Free Energy Profile of Tubulin Straight-Bent Conformational Changes, with Implications for Microtubule Assembly and Drug Discovery

David A. Agard,Lili X. Peng,Massimiliano Bonomi,Matthew P. Jacobson,Monica T. Hsu

Mathematical Modeling of the Phoenix Rising Pathway

Chad Liu,Chuan-Yuan Li,Fan Yuan

Cell Type Specific Alterations in Interchromosomal Networks across the Cell Cycle

Andrew J. Fritz,Branislav Stojkovic,Hu Ding,Jinhui Xu,Ronald Berezney,Sambit Bhattacharya

A Bayesian Framework to Identify Methylcytosines from High-Throughput Bisulfite Sequencing Data

Bingyu Chen,Fengbiao Mao,Honghu Wu,Jinyu Wu,Mingcong You,Qi Liu,Qing Xie,Wanshi Cai,Zhen Wang,Zhong Sheng Sun

Memory Maintenance in Synapses with Calcium-Based Plasticity in the Presence of Background Activity

David Higgins,Michael Graupner,Nicolas Brunel

From the Phenomenology to the Mechanisms of Consciousness: Integrated Information Theory 3.0

Giulio Tononi,Larissa Albantakis,Masafumi Oizumi

Pathway Thermodynamics Highlights Kinetic Obstacles in Central Metabolism

Arren Bar-Even,Avi Flamholz,Ed Reznik,Elad Noor,Ron Milo,Wolfram Liebermeister

Combined Role of Seizure-Induced Dendritic Morphology Alterations and Spine Loss in Newborn Granule Cells with Mossy Fiber Sprouting on the Hyperexcitability of a Computer Model of the Dentate Gyrus

Antonio C. Roque,Julian Tejada,Norberto Garcia-Cairasco

NbIT - A New Information Theory-Based Analysis of Allosteric Mechanisms Reveals Residues that Underlie Function in the Leucine Transporter LeuT

Harel Weinstein,Michael V. LeVine

Modeling Dynamics of Cell-to-Cell Variability in TRAIL-Induced Apoptosis Explains Fractional Killing and Predicts Reversible Resistance

Dirk Drasdo,Fran？ois Bertaux,Gregory Batt,Szymon Stoma

Stress and Strain Provide Positional and Directional Cues in Development

Behruz Bozorg,Henrik J？nsson,Pawel Krupinski

ATPase Subdomain IA Is a Mediator of Interdomain Allostery in Hsp70 Molecular Chaperones

Ignacio J. General,Ivet Bahar,Lila M. Gierasch,Mandy E. Blackburn,Wenzhi Mao,Ying Liu

Exploration of the Dynamic Properties of Protein Complexes Predicted from Spatially Constrained Protein-Protein Interaction Networks

Aaron Tsay,Eric A. Yen,Jackie Vogel,Jerome Waldispuhl

Regression Analysis of Combined Gene Expression Regulation in Acute Myeloid Leukemia

Minggao Liang,Yue Li,Zhaolei Zhang

Population Decoding in Rat Barrel Cortex: Optimizing the Linear Readout of Correlated Population Responses

Colin W. G. Clifford,Ehsan Arabzadeh,James S. McDonald,Mehdi Adibi

Enumeration of Smallest Intervention Strategies in Genome-Scale Metabolic Networks

Axel von Kamp,Steffen Klamt

Beyond Muscles Stiffness: Importance of State-Estimation to Account for Very Fast Motor Corrections

Frédéric Crevecoeur,Stephen H. Scott

Depletion of the Chromatin Looping Proteins CTCF and Cohesin Causes Chromatin Compaction: Insight into Chromatin Folding by Polymer Modelling

Dieter W. Heermann,Erik M. M. Manders,Hansjoerg Jerabek,Mariliis Tark-Dame,Roel van Driel

Axonal Noise as a Source of Synaptic Variability

A. Aldo Faisal,Ali Neishabouri

Optimal Recall from Bounded Metaplastic Synapses: Predicting Functional Adaptations in Hippocampal Area CA3

Cristina Savin,Máté Lengyel,Peter Dayan

Structurally-Constrained Relationships between Cognitive States in the Human Brain

Amy Frithsen,Ann M. Hermundstad,Arianne Johnson,Christine M. Tipper,Danielle S. Bassett,Elissa M. Aminoff,Jean M. Carlson,Kevin S. Brown,Michael B. Miller,Scott T. Grafton

Reciprocal Regulation as a Source of Ultrasensitivity in Two-Component Systems with a Bifunctional Sensor Kinase

Ronny Straube

Some Work and Some Play: Microscopic and Macroscopic Approaches to Labor and Leisure

Peter Dayan,Peter Shizgal,Ritwik K. Niyogi

Correction: An In-Silico Model of Lipoprotein Metabolism and Kinetics for the Evaluation of Targets and Biomarkers in the Reverse Cholesterol Transport Pathway

The PLOS Computational Biology Staff

Correction: A Likelihood-Based Approach to Identifying Contaminated Food Products Using Sales Data: Performance and Challenges

The PLOS Computational Biology Staff

Yielding Elastic Tethers Stabilize Robust Cell Adhesion

Jonathon P. Luo,Matt J. Whitfield,Wendy E. Thomas

IDEPI: Rapid Prediction of HIV-1 Antibody Epitopes and Other Phenotypic Features from Sequence Data Using a Flexible Machine Learning Platform

Ben Murrell,Davey M. Smith,Dennis R. Burton,Douglas D. Richman,Konrad Scheffler,N. Lance Hepler,Pascal Poignard,Sergei L. Kosakovsky Pond,Steven Weaver

Feedback Signals in Myelodysplastic Syndromes: Increased Self-Renewal of the Malignant Clone Suppresses Normal Hematopoiesis

Anna Marciniak-Czochra,Anthony D. Ho,Bj？rn Rath,Hanna Braun,Julia Fr？bel,Tamme W. Goecke,Thomas Schroeder,Thomas Stiehl,Thomas Walenda,Ulrich Germing,Wolfgang Wagner

Bayesian Analysis for Inference of an Emerging Epidemic: Citrus Canker in Urban Landscapes

Alex R. Cook,Christopher A. Gilligan,Franco M. Neri,Gavin J. Gibson,Tim R. Gottwald

Synchronization of Isolated Downstates (K-Complexes) May Be Caused by Cortically-Induced Disruption of Thalamic Spindling

Burke Q. Rosen,Eric Halgren,Hélène Bastuji,Ki-Young Jung,Marc Rey,Maxim Bazhenov,Rachel A. Mak-McCully,Stephen R. Deiss,Sydney S. Cash,Terrence J. Sejnowski

Characterizing Protein Interactions Employing a Genome-Wide siRNA Cellular Phenotyping Screen

Apichat Suratanee,Ellen Ramminger,Erich Wanker,Guillermo Marcus,Heiko Mannsperger,Karl Rohr,Marcus Oswald,Markus Gipp,Martin H. Schaefer,Matthew J. Betts,Miguel A. Andrade-Navarro,Nathalie Harder,Rainer K？nig,Reinhard M？nner,Robert B. Russell,Roland Eils,Zita Soons

©2008-2020 OALib, Inc | Public user content licensed CC-BY 4.0 unless otherwise specified. OALib ISSN Online: 2333-9721 OALib ISSN Print: 2333-9705