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ISSN: 2333-9721
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A Virtual Infection Model Quantifies Innate Effector Mechanisms and Candida albicans Immune Escape in Human Blood

Kerstin Hünniger,Kristin Bieber,Marc Thilo Figge,Oliver Kurzai,Ronny Martin,Teresa Lehnert

Differential Adhesion between Moving Particles as a Mechanism for the Evolution of Social Groups

Leonardo Gregory Brunnet,Silvia De Monte,Thomas Garcia

A Novel Bayesian Method for Detection of APOBEC3-Mediated Hypermutation and Its Application to Zoonotic Transmission of Simian Foamy Viruses

Christopher T. Small,Frederick A. Matsen IV,Gregory A. Engel,Karen L. Craig,Khanh Soliven,Lisa Jones-Engel,M. Kamrul Hasan,Maxine L. Linial,Michael Emerman,Mostafa M. Feeroz,Xiaoxing Wang

Pep2Path: Automated Mass Spectrometry-Guided Genome Mining of Peptidic Natural Products

Alexey Melnik,Don D. Nguyen,Eriko Takano,Marnix H. Medema,Pieter C. Dorrestein,Rainer Breitling,Yared Paalvast

Quantifying and Predicting the Effect of Exogenous Interleukin-7 on CD4+T Cells in HIV-1 Infection

Ana Jarne,Christine Lacabaratz,Daniel Commenges,Irini Sereti,Julia Drylewicz,Michael M. Lederman,Mélanie Prague,Rafick-Pierre Sekaly,Rodolphe Thiébaut,Stéphanie Beq,Thérèse Croughs,Yves Lévy

Dynamic Conformational Change Regulates the Protein-DNA Recognition: An Investigation on Binding of a Y-Family Polymerase to Its Target DNA

Brian A. Maxwell,Fei Liu,Haijun Wang,Jin Wang,Wei Han,Xiakun Chu,Yong Wang,Zucai Suo

A Signature of Attractor Dynamics in the CA3 Region of the Hippocampus

César Rennó-Costa,John E. Lisman,Paul F. M. J. Verschure

Phosphate Sink Containing Two-Component Signaling Systems as Tunable Threshold Devices

Birgit E. Scharf,Elisenda Feliu,Munia Amin,Orkun S. Soyer,Steven L. Porter,Varun B. Kothamachu

Coiled-Coil Proteins Facilitated the Functional Expansion of the Centrosome

Andreas Beyer,Anthony A. Hyman,Michael Kuhn

Multiscale Approach to the Determination of the Photoactive Yellow Protein Signaling State Ensemble

Bradley Lambeth,Cecilia Clementi,Jocelyne Vreede,Mary A. Rohrdanz,Wenwei Zheng

Putting Theory to the Test: Which Regulatory Mechanisms Can Drive Realistic Growth of a Root?

Dirk De Vos,Gerrit T. S. Beemster,Jan Broeckhove,Kris Vissenberg

Linkage of Viral Sequences among HIV-Infected Village Residents in Botswana: Estimation of Linkage Rates in the Presence of Missing Data

Nicole Bohme Carnegie,Rui Wang,Victor De Gruttola,Vladimir Novitsky

Interference and Shaping in Sensorimotor Adaptations with Rewards

Arthur Leblois,David Hansel,Ran Darshan

Place Cell Rate Remapping by CA3 Recurrent Collaterals

Hosam N. Yousif,Terrence J. Sejnowski,Trygve Solstad

AprioriGWAS, a New Pattern Mining Strategy for Detecting Genetic Variants Associated with Disease through Interaction Effects

Jurg Ott,Qingrun Zhang,Quan Long

Intrinsic Noise Induces Critical Behavior in Leaky Markovian Networks Leading to Avalanching

Garrett Jenkinson,John Goutsias

Canonical Correlation Analysis for Gene-Based Pleiotropy Discovery

Colin Campbell,Ian N. M. Day,Jose A. Seoane,Juan P. Casas,Tom R. Gaunt

The SH2 Domain Regulates c-Abl Kinase Activation by a Cyclin-Like Mechanism and Remodulation of the Hinge Motion

Antonio S. Torralba,Francesco L. Gervasio,Giulio Superti-Furga,Ludovico Sutto,Maria W. Górna,Nicole D？lker

A Computational Model of the Fetal Circulation to Quantify Blood Redistribution in Intrauterine Growth Restriction

Bart H. Bijens,Eduard Gratacos,Fatima Crispi,Georgina Palau,Monica Cruz-Lemini,Oscar Camara,Patricia Garcia-Canadilla,Paula A. Rudenick

Model Selection in Systems Biology Depends on Experimental Design

Chris P. Barnes,Daniel Silk,Michael P. H. Stumpf,Paul D. W. Kirk,Tina Toni

An HIV Epidemic Model Based on Viral Load Dynamics: Value in Assessing Empirical Trends in HIV Virulence and Community Viral Load

Geoffrey S. Gottlieb,James I. Mullins,John E. Mittler,Joshua T. Herbeck

Ensembles of Spiking Neurons with Noise Support Optimal Probabilistic Inference in a Dynamically Changing Environment

Robert Legenstein,Wolfgang Maass

Linking Myometrial Physiology to Intrauterine Pressure; How Tissue-Level Contractions Create Uterine Contractions of Labor

Peter Barendse,Roger C. Young

Lipid Clustering Correlates with Membrane Curvature as Revealed by Molecular Simulations of Complex Lipid Bilayers

David Shorthouse,Heidi Kolds？,Jean Hélie,Mark S. P. Sansom

CGBayesNets: Conditional Gaussian Bayesian Network Learning and Inference with Mixed Discrete and Continuous Data

Hsun-Hsien Chang,Michael J. McGeachie,Scott T. Weiss

Computational Modeling of Allosteric Regulation in the Hsp90 Chaperones: A Statistical Ensemble Analysis of Protein Structure Networks and Allosteric Communications

Gennady M. Verkhivker,Kristin Blacklock

Optimal Screening Strategies for Healthcare Associated Infections in a Multi-Institutional Setting

Aaron C. Miller,Linnea A. Polgreen,Philip M. Polgreen

Task-Specific Response Strategy Selection on the Basis of Recent Training Experience

C. Shawn Green,Jacqueline M. Fulvio,Paul R. Schrater

Bioinformatics Projects Supporting Life-Sciences Learning in High Schools

Ana Godinho,Isabel Marques,José B. Pereira-Leal,Maria Jo？o Dias,Paulo Almeida,Renato Alves

Environmental and State-Level Regulatory Factors Affect the Incidence of Autism and Intellectual Disability

Andrey Rzhetsky,Christopher S. Lyttle,Edwin H. Cook Jr,Kanix Wang,Robert D. Gibbons,Russ B. Altman,Steven C. Bagley

A Deterministic Model Predicts the Properties of Stochastic Calcium Oscillations in Airway Smooth Muscle Cells

Graham Donovan,James Sneyd,Michael J. Sanderson,Pengxing Cao,Xiahui Tan

Tracing the Evolution of Lineage-Specific Transcription Factor Binding Sites in a Birth-Death Framework

Jian Ma,Ken Daigoro Yokoyama,Yang Zhang

Defining the Estimated Core Genome of Bacterial Populations Using a Bayesian Decision Model

Alison J. Cody,Andries J. van Tonder,Angela B. Brueggemann,Anne von Gottberg,Chris L. Farmer,Dorothea M. C. Hill,James E. Bray,Julian Parkhill,Keith A. Jolley,Keith P. Klugman,Martin C. J. Maiden,Shilan Mistry,Stephen D. Bentley

Detecting Functional Divergence after Gene Duplication through Evolutionary Changes in Posttranslational Regulatory Sequences

Alan M. Moses,Alex N. Nguyen Ba,Bob Strome,Christian R. Landry,Eric L. Weiss,Isabelle Gagnon-Arsenault,Jonathan Desmond,Jun Jie Hua

Pyranose Dehydrogenase Ligand Promiscuity: A Generalized Approach to Simulate Monosaccharide Solvation, Binding, and Product Formation

Chris Oostenbrink,Dietmar Haltrich,Lin Zhixiong,Michael M. H. Graf,Urban Bren,Wilfred F. van Gunsteren

The Role of Membrane-Mediated Interactions in the Assembly and Architecture of Chemoreceptor Lattices

Christoph A. Haselwandter,Ned S. Wingreen

Epigenetics Decouples Mutational from Environmental Robustness. Did It Also Facilitate Multicellularity?

Aviv Bergman,Saurabh Gombar,Thomas MacCarthy

The Self-Limiting Dynamics of TGF-β Signaling In Silico and In Vitro, with Negative Feedback through PPM1A Upregulation

Hanry Yu,Inn Chuan Ng,Jacob K. White,Junjie Wang,Lisa Tucker-Kellogg,P. S. Thiagarajan,Ruirui Jia

Messages Do Diffuse Faster than Messengers: Reconciling Disparate Estimates of the Morphogen Bicoid Diffusion Coefficient

Alejandro Colman-Lerner,John E. Pearson,Lorena Sigaut,Silvina Ponce Dawson

Model-Based Analysis for Qualitative Data: An Application in Drosophila Germline Stem Cell Regulation

Ann E. Rundell,David M. Umulis,Gregery T. Buzzard,Michael Pargett

Augmenting Microarray Data with Literature-Based Knowledge to Enhance Gene Regulatory Network Inference

Dongwook Shin,Guocai Chen,Halil Kilicoglu,Michael J. Cairelli,Thomas C. Rindflesch

Contradictory Behavioral Biases Result from the Influence of Past Stimuli on Perception

Itay Lieder,Merav Ahissar,Ofri Raviv,Yonatan Loewenstein

Molecular Dynamics Study of the Opening Mechanism for DNA Polymerase I

Bill R. Miller III,Carol A. Parish,Eugene Y. Wu

Quantitative Protein Localization Signatures Reveal an Association between Spatial and Functional Divergences of Proteins

Danai Laksameethanasan,Lit-Hsin Loo,Yi-Ling Tung

Construction and Validation of a Regulatory Network for Pluripotency and Self-Renewal of Mouse Embryonic Stem Cells

Ana Sevilla,Avi Ma'ayan,Huilei Xu,Ihor R. Lemischka,Yen-Sin Ang

Bursts and Heavy Tails in Temporal and Sequential Dynamics of Foraging Decisions

Hyeran Jang,Jaeseung Jeong,Jerald D. Kralik,Kanghoon Jung

Collective Learning and Optimal Consensus Decisions in Social Animal Groups

Albert B. Kao,Andrew Hartnett,Colin Torney,Iain D. Couzin,Noam Miller

Modular Composition of Gene Transcription Networks

Andras Gyorgy,Domitilla Del Vecchio

Structure, Dynamics and Implied Gating Mechanism of a Human Cyclic Nucleotide-Gated Channel

Charlotta Sch？rfe,Debora S. Marks,Nir Ben-Tal,Turkan Haliloglu,Yana Gofman

Intrinsic Neuronal Properties Switch the Mode of Information Transmission in Networks

Adrienne L. Fairhall,Julijana Gjorgjieva,Rebecca A. Mease,William J. Moody

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