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ISSN: 2333-9721
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ISSN Print: 1990-2017

ISSN Online:

主页: https://journals.plos.org/plosmedicine/

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A reduced-carbohydrate and lactose-free formulation for stabilization among hospitalized children with severe acute malnutrition: A double-blind, randomized controlled trial

André Briend,Anneke C. Muller Kobold,Benjamin Allubha,Betty Owor,Celine Bourdon,Christian J. Versloot,Deborah A. van den Brink,Emmanuel Chimwezi,Fauzat Hamid,Greg Fegan,Isabel Potani,James A. Berkley,Johnstone Thitiri,Laura Mwalekwa,Marjon Feenstra,Marko Kerac,Moses Ngari,Neema Mturi,Patrick F. van Rheenen,Rehema Ali,Robert H. J. Bandsma,Rosalie H. Bartels,Victor Bandika,Wieger Voskuijl

Setting targets for HIV/AIDS—What lessons can be learned from other disease control programmes?

David Heymann,Jamie Enoch,Mishal Khan,Osman Dar,Richard Hayes,Sophie Mathewson,Tazeem Bhatia

Associations of genetically determined iron status across the phenome: A mendelian randomization study

Abbas Dehghan,Ang Zhou,Ann P. Walker,Beben Benyamin,Dipender Gill,Elina Hypp？nen,Evangelos Evangelou,Fotios Koskeridis,Grace Monori,Ioanna Tzoulaki,Konstantinos K. Tsilidis,Luke S. P. Moore,Mike Laffan,Paul Elliott

Trends in prescription opioid use and dose trajectories before opioid use disorder or overdose in US adults from 2006 to 2016: A cross-sectional study

Almut G. Winterstein,Cheng Chen,Roger Fillingim,Siegfried O. Schmidt,Yu-Jung Jenny Wei

Addressing the context and consequences of substance use, misuse, and dependence: A global imperative

Alexander C. Tsai,Margarita Alegría,Steffanie A. Strathdee

Association of preterm birth with lipid disorders in early adulthood: A Swedish cohort study

Casey Crump,Jan Sundquist,Kristina Sundquist

Prediction of recurrent venous thrombosis in all patients with a first venous thrombotic event: The Leiden Thrombosis Recurrence Risk Prediction model (L-TRRiP)

Astrid van Hylckama Vlieg,Frits R. Rosendaal,Jasmijn F. Timp,John-Bjarne Hansen,Saskia le Cessie,Sigrid K. Braekkan,Suzanne C. Cannegieter,Willem M. Lijfering

High-resolution mapping of tuberculosis transmission: Whole genome sequencing and phylogenetic modelling of a cohort from Valencia Region, Spain

Adelina Gimeno-Gascón,Ana Gil-Brusola,Bárbara Gomila-Sard,Caroline Colijn,Concepción Gimeno,Coral Martín-González,Damiana González-Granda,David Navarro,Elvira Pérez,Ester Colomer-Roig,Herme Vanaclocha,Irving Cancino-Mu？oz,Isabel Escribano,I？aki Comas,Javier Colomina,Josep Prat,José Luis López-Hontangas,Juan Carlos Rodríguez,Juan J. Camarena,Luis M. Villamayor,Manuela Torres-Puente,María Borrás-Má？ez,María Montserrat Ruiz-García,María Navarro,María Remedio Guna-Serrano,Montserrat Bosque,Nieves Gonzalo-Jiménez,Nieves Orta,Oscar Esparcia-Rodríguez,Rafael Borrás,Rosario Moreno-Mu？oz,Yuanwei Xu

Provision of postpartum care to women giving birth in health facilities in sub-Saharan Africa: A cross-sectional study using Demographic and Health Survey data from 33 countries

David Macleod,Emma Radovich,Etienne V. Langlois,Kerry L. M. Wong,Lenka Benova,Onikepe Owolabi,Oona M. R. Campbell

Impact on child acute malnutrition of integrating small-quantity lipid-based nutrient supplements into community-level screening for acute malnutrition: A cluster-randomized controlled trial in Mali

Agnes Le Port,Amanda Zongrone,Elodie Becquey,Francisco M. Barba,Jef L. Leroy,Lieven Huybregts,Marie T. Ruel,Rahul Rawat

Community-based football in men with prostate cancer: 1-year follow-up on a pragmatic, multicentre randomised controlled trial

Anders Bojer J？rgensen,Bente Langdahl,Christoffer Johansen,Eik Dybboe Bjerre,Julie Midtgaard,Klaus Brasso,Mads Hvid Poulsen,Michael Borre,Mikael R？rth,Peter Busch ？stergren,Peter Krustrup,S？ren S？rensen Madsen,Thomas Hindborg Petersen

Portrayals of mental illness, treatment, and relapse and their effects on the stigma of mental illness: Population-based, randomized survey experiment in rural Uganda

Alexander C. Tsai,Bernard Kakuhikire,Charles Baguma,Christine E. Cooper-Vince,David R. Bangsberg,Jessica M. Perkins,Justin D. Rasmussen,Scholastic Ashaba

Suspected heroin-related overdoses incidents in Cincinnati, Ohio: A spatiotemporal analysis

Evaline Xie,Forrest W. Crawford,Gregg S. Gonsalves,J. Tyler Copple,Joshua L. Warren,Kathryn McConnell,Tyler Johnson,Zehang Richard Li

Testosterone replacement in young male cancer survivors: A 6-month double-blind randomised placebo-controlled trial

Diana M. Greenfield,Emma Best,Helen Marshall,Isabelle L. Smith,James Ashton,Jayne Swain,Jennifer S. Walsh,John A. Snowden,Julia M. Brown,Richard J. Ross,Robert E. Coleman,Robert Huddart

Malaria morbidity and mortality following introduction of a universal policy of artemisinin-based treatment for malaria in Papua, Indonesia: A longitudinal surveillance study

Angela Devine,Enny Kenangalem,Faustina Helena Burdam,Ferry Chalfein,Franciscus Thio,Govert Waramori,Jeanne Rini Poespoprodjo,Julie A. Simpson,Jutta Marfurt,Ketut Gdeumana,Michael J. Bangs,Nicholas M. Anstey,Nicholas M. Douglas,Pasi Penttinen,Paulus Sugiarto,Prayoga,Ric N. Price,Rintis Noviyanti,Shunmay Yeung,Yati Soenarto

Chronic physical conditions and risk for perinatal mental illness: A population-based retrospective cohort study

Andrew S. Wilton,Astrid Guttmann,Cindy-Lee Dennis,Hilary K. Brown,Joel G. Ray,Simone N. Vigod

Evaluation of RESPOND, a patient-centred program to prevent falls in older people presenting to the emergency department with a fall: A randomised controlled trial

Andrew Forbes,Anna Barker,Anne-Marie Hill,Caroline Brand,Christopher Etherton-Beer,Darshini Ayton,De Villiers Smit,Eileen Boyle,Ellen MacDonald,Glenn Arendts,Judy Lowthian,Julie Redfern,Keith Hill,Leon Flicker,Nicholas Waldron,Peter Cameron,Peter Hunter,Renata Morello,Samuel R. Nyman,Terry Haines

Prescription of benzodiazepines, z-drugs, and gabapentinoids and mortality risk in people receiving opioid agonist treatment: Observational study based on the UK Clinical Practice Research Datalink and Office for National Statistics death records

Colin Steer,John Macleod,John Marsden,John Strang,Kate Tilling,Matthew Hickman,Rosie Cornish,Tim Millar

Development of new TB regimens: Harmonizing trial design, product registration requirements, and public health guidance

Andrew A. Vernon,Christian Lienhardt,Marco Cavaleri,Payam Nahid,Sumati Nambiar

Octreotide-LAR in later-stage autosomal dominant polycystic kidney disease (ALADIN 2): A randomized, double-blind, placebo-controlled, multicenter trial

Alessandro Villa,Andrea Remuzzi,Anna Caroli,Annalisa Perna,Antonio Granata,Antonio Pisani,Eleonora Riccio,Fabiola Carrara,Flavio Gaspari,Giovanni Morana,Giuseppe Remuzzi,Massimo Imbriaco,Matias Trillini,Mauro Dugo,Michele Figuera,Monica Cortinovis,Nadia Rubis,Norberto Perico,Piero Ruggenenti,Sandro Sironi,Sara Gamba,Silvia Prandini,for the ALADIN 2 Study Group

Variation in blood pressure and long-term risk of dementia: A population-based cohort study

Albert Hofman,Frank J. Wolters,Lori B. Chibnik,M. Arfan Ikram,M. Kamran Ikram,Silvan Licher,Yuan Ma

Supervised injection facility use and all-cause mortality among people who inject drugs in Vancouver, Canada: A cohort study

Evan Wood,Kanna Hayashi,M-J Milloy,Mary Clare Kennedy,Thomas Kerr

Effect of a scaled-up neonatal resuscitation quality improvement package on intrapartum-related mortality in Nepal: A stepped-wedge cluster randomized controlled trial

Abhishek Gurung,Anna Bergstr？m,Ashish KC,Bijay Kumar Jha,Helena Litorp,Johan Wrammert,Leif Eriksson,Mats M？lqvist,Olivia Brunell,Omkar Basnet,Prajwal Paudel,Sunil Gajurel,Sushil Karki,Sushil Nath Pyakuryal,Uwe Ewald

Screening for breech presentation using universal late-pregnancy ultrasonography: A prospective cohort study and cost effectiveness analysis

Alexandros A. Moraitis,Alison Dacey,David Wastlund,Edward C. F. Wilson,Gordon C. S. Smith,Ulla Sovio

Mediating roles of preterm birth and restricted fetal growth in the relationship between maternal education and infant mortality: A Danish population-based cohort study

Aolin Wang,Bo Fu,Carsten Obel,Guoyou Qin,Jialiang Li,Jiong Li,J？rn Olsen,Onyebuchi A. Arah,Sven Cnattingius,Yongfu Yu,Zeyan Liew

Mother’s dietary quality during pregnancy and offspring’s dietary quality in adolescence: Follow-up from a national birth cohort study of 19,582 mother–offspring pairs

Anne Ahrendt Bjerregaard,Inge Tetens,Sjurdur Frodi Olsen,Thorhallur Ingi Halldorsson

Lay health supporters aided by mobile text messaging to improve adherence, symptoms, and functioning among people with schizophrenia in a resource-poor community in rural China (LEAN): A randomized controlled trial

Dong (Roman) Xu,Eric D. Caine,Hua He,James P. Hughes,Jane Simoni,Juan Nie,Meijuan Lin,Shuiyuan Xiao,Stephen Gloyd,Wenjie Gong,Wenjun He,Yeqing Yuan

Incidence of hospitalization for infection among patients with hepatitis B or C virus infection without cirrhosis in Taiwan: A cohort study

Chia-Hsuin Chang,Hsi-Chieh Chen,Jiun-Ling Wang,Li-Chiu Wu,Yaa-Hui Dong,Yen-Chieh Lee

Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies

Anneke C. Hesseling,Anthony J. Garcia-Prats,H. Simon Schaaf,Heather R. Draper,Jana Winckler,Lubbe Wiesner,Maria Garcia-Cremades,Rada M. Savic

Associations of genetics, behaviors, and life course circumstances with a novel aging and healthspan measure: Evidence from the Health and Retirement Study

Chao Ma,Eileen M. Crimmins,Morgan E. Levine,Thomas M. Gill,Xi Chen,Zuyun Liu

Planned mode of delivery after previous cesarean section and short-term maternal and perinatal outcomes: A population-based record linkage cohort study in Scotland

Jennifer J. Kurinczuk,Kathryn E. Fitzpatrick,Maria A. Quigley,Sohinee Bhattacharya

Text messaging and brief phone calls for weight loss in overweight and obese English- and Spanish-speaking adults: A 1-year, parallel-group, randomized controlled trial

Cheryl L. Rock,Elva Arredondo,Fred Raab,Gina Merchant,Greg J. Norman,Job G. Godino,Julie Kolodziejczyk,Kevin Patrick,Lindsay Dillon,Maggie Crawford,Natalie M. Golaszewski,Simon Marshall,Sonia Jain,William G. Griswold

Psychological, social, and welfare interventions for torture survivors: A systematic review and meta-analysis of randomised controlled trials

Amanda C. de C. Williams,Aseel Hamid,Nimisha Patel

Who elects the weekend?

Chaim M. Bell,Lauren Lapointe-Shaw

The safety of double- and triple-drug community mass drug administration for lymphatic filariasis: A multicenter, open-label, cluster-randomized study

Adinarayanan Srividya,Andrew C. Steer,Anita Sircar,Charles W. Goss,Christine Dubray,Christopher L. King,Gary J. Weil,Jean Frantz Lemoine,Josaia Samuela,Joshua Bogus,Kaliannagounder Krishnamoorthy,Katiuscia K. O’Brian,Kenneth B. Schechtman,Leanne J. Robinson,Michael Christian,Moses Laman,Myra Hardy,Peter U. Fischer,Purushothaman Jambulingam,Swaminathan Subramanian,Taniawati Supali,Vijesh Sridhar Kuttiat,Yenny Djuardi,the DOLF IDA Safety Study Group

Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis

Andrew R. Wood,Andrew T. Hattersley,Bridget A. Knight,Debbie A. Lawlor,Jessica Tyrrell,Maria-Carolina Borges,Rachel M. Freathy,Robin N. Beaumont,Susan M. Ring,William D. Thompson

Risk and protective factors for child development: An observational South African birth cohort

Andrea M. Rehman,Catherine J. Wedderburn,Dan J. Stein,Heather J. Zar,Jacob A. M. Stadler,Kirsten Ann Donald,Nadia Hoffman,Nastassja Koen,Raymond T. Nhapi,Whitney Barnett

HIV self-testing alone or with additional interventions, including financial incentives, and linkage to care or prevention among male partners of antenatal care clinic attendees in Malawi: An adaptive multi-arm, multi-stage cluster randomised trial

Augustine T. Choko,Aurelia Lepine,Cheryl C. Johnson,Doreen Sakala,Elizabeth L. Corbett,Hendramoorthy Maheswaran,Katherine Fielding,Moses Kumwenda,Nigel Stallard,Richard Hayes,Thokozani Kalua

Airway obstruction and bronchial reactivity from age 1 month until 13 years in children with asthma: A prospective birth cohort study

Bo Lund Chawes,Hans Bisgaard,Henrik Wegener Hallas,Jakob Stokholm,Klaus B？nnelykke,Lambang Arianto,Morten Arendt Rasmussen

Evaluation of approaches to strengthen civil registration and vital statistics systems: A systematic review and synthesis of policies in 25 countries

Aleya Khalifa,Amitabh Bipin Suthar,Carla AbouZahr,Doris Ma Fat,Erin Nichols,Kristen Wenz,Samuel Lantei Mills,Sherry Yin,Srdjan Mrkic

The importance of adherence in tuberculosis treatment clinical trials and its relevance in explanatory and pragmatic trials

Andrew Vernon,Katherine Fielding,Lori Dodd,Payam Nahid,Rada Savic

Effects of single and integrated water, sanitation, handwashing, and nutrition interventions on child soil-transmitted helminth and Giardia infections: A cluster-randomized controlled trial in rural Kenya

Amy J. Pickering,Audrie Lin,Benard Chieng,Benjamin F. Arnold,Christine P. Stewart,Clair Null,Gouthami Rao,Holly N. Dentz,Jenna Swarthout,Jimmy Kihara,John M. Colford Jr.,Kendra Byrd,Lauren Steinbaum,Marina Papaiakovou,Marlene Wolfe,MaryAnne Mureithi,Nils Pilotte,Priscah Cheruiyot,Ryan Mahoney,Sammy M. Njenga,Steven A. Williams,Theodora Meerkerk

No causal effects of serum urate levels on the risk of chronic kidney disease: A Mendelian randomization study

Daniel M. Jordan,Girish Nadkarni,Hong-Hee Won,Hyon K. Choi,Marie Verbanck,Ron Do,Ruth Topless,Tony R. Merriman

The Flooring for Injury Prevention (FLIP) Study of compliant flooring for the prevention of fall-related injuries in long-term care: A randomized trial

Andrew C. Laing,Chantelle C. Lachance,Dawn C. Mackey,Fabio Feldman,Peiwei T. Wang,Pet M. Leung,Stephen N. Robinovitch,X. Joan Hu

Maternal exposure to intimate partner violence and breastfeeding practices in 51 low-income and middle-income countries: A population-based cross-sectional study

Briony Steele,Debbie Marais,Hana Nekatebeb Bekele,Jennifer Coles,Olalekan A. Uthman,Peggy Koniz-Booher,Ricardo Uauy,Rishi Caleyachetty,Rocio Martín-Ca？avate

Acute kidney injury and adverse renal events in patients receiving SGLT2-inhibitors: A systematic review and meta-analysis

Bernhard M. W. Schmidt,Eva Dumann,Hermann Haller,Jan Menne

Wirelessly observed therapy compared to directly observed therapy to confirm and support tuberculosis treatment adherence: A randomized controlled trial

Amanda J. Tucker,Anya Umlauf,Charles A. Peloquin,Constance A. Benson,Florin Vaida,Jonathan Gonzalez Garcia,Julie Low,Kathleen Moser,Sara H. Browne,Terrence Blaschke

Mental disorders and intimate partner violence perpetrated by men towards women: A Swedish population-based longitudinal study

Alejo J. Nevado-Holgado,Brian M. D’Onofrio,Henrik Larsson,Louise M. Howard,Rongqin Yu,Seena Fazel,Yasmina Molero

Hospital admission on weekends for patients who have surgery and 30-day mortality in Ontario, Canada: A matched cohort study

Anne-Marie Leo,Asad Siddiqui,David Levin,Hannah Wunsch,James D. O’Leary,Mark W. Crawford

Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study

Anshul Kundaje,Anubha Mahajan,Erik Ingelsson,Manuel A. Rivas,Mark I. McCarthy,Michael Wainberg,Nasa Sinnott-Armstrong

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