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OALib Journal期刊
ISSN: 2333-9721
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主页: https://journals.plos.org/plosbiology/

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Prophylactic TLR9 stimulation reduces brain metastasis through microglia activation

Alisa Lubart,Amit Benbenishty,Ariella Glasner,Azzurra Cottarelli,David Kain,Dritan Agalliu,Lee Shaashua,Lior Mayo,Malak Amer,Meital Gadrich,Neta Erez,Pablo Blinder,Shamgar Ben-Eliyahu

A large-scale pedigree resource of wheat reveals evidence for adaptation and selection by breeders

Ian J. Mackay,James Cockram,James Elderfield,John M. Hickey,Keith A. Gardner,Nick Fradgley,Phil Howell,Robert Jackson

Dynamic enhancers control skeletal muscle identity and reprogramming

Amanda L. Allred,Christopher R. Futtner,Grant D. Barish,Krithika Ramachandran,Madhavi D. Senagolage,Meredith A. Sommars,Yasuhiro Omura

Historical contingency in the evolution of antibiotic resistance after decades of relaxed selection

Jasper B. Gomez,Kyle J. Card,Richard E. Lenski,Thomas LaBar

The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7

Aloys Schepers,Ambrosius P. Snijders,Anika Marko,Chris P. Ponting,Dominik Boos,Kerstin K？hler,Luis Sanchez-Pulido,Regina Feederle,Verena H？fer

A transient helix in the disordered region of dynein light intermediate chain links the motor to structurally diverse adaptors for cargo transport

Alexandra Born,Ana X. Carvalho,Beat V？geli,Cátia Carvalho,Daniel J. Barbosa,José B. Gama,Maxwell McCabe,Morkos A. Henen,Parker J. Nichols,Reto Gassmann,Ricardo Celestino

Activation of the intrinsic fibroinflammatory program in adult pancreatic acinar cells triggered by Hippo signaling disruption

Francis E. Sharkey,Howard C. Crawford,Janice Deng,Jun Liu,Michael Nipper,Ming Gao,Pei Wang,Randy L. Johnson,Yidong Chen

Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue

Bin Zhang,Hao Fan,Jianan Guo,Kathleen M. Giacomini,Ligong Chen,Lili Cheng,Linkang Zhou,Peng Li,Qi Luo,Siqi Li,Sook Wah Yee,Wenxin Song,Ye Liu,Yuedong Huang,Yuping Zhang,Zhilong Ma,Zicheng Li,Ziyi Meng

Inhibition of Notch signaling rescues cardiovascular development in Kabuki Syndrome

Bradley L. Demarest,H. Joseph Yost,Maria de los Angeles Serrano,Martin Tristani-Firouzi,Tarlynn Tone-Pah-Hote

Item-specific delay activity demonstrates concurrent storage of multiple active neural representations in working memory

David W. Sutterer,Edward Awh,Edward K. Vogel,Joshua J. Foster,Kirsten C. S. Adam

V1 interneurons regulate the pattern and frequency of locomotor-like activity in the neonatal mouse spinal cord

Melanie Falgairolle,Michael J. O’Donovan

Variation in actuarial senescence does not reflect life span variation across mammals

Guillaume Péron,Jean-Fran？ois Lema？tre,Jean-Michel Gaillard,Morgane Tidière,Victor Ronget

Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors

Dan Su,Hong Li,Jianping Lin,Lei Cao,Ling Zhu,Pan Yang,Pi Liu,Qiang Gao,Xiangxi Wang,Yao Sun,Zihe Rao

CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor

Christopher J. Shoemaker,Nicholas R. Weir,Nicole J. Polyakov,Sebastian W. Schultz,Tina Q. Huang,Vladimir Denic

GPCRs show widespread differential mRNA expression and frequent mutation and copy number variation in solid tumors

Hannah Carter,Kevin Moyung,Krishna Sriram,Paul A. Insel,Ross Corriden

Contest models highlight inherent inefficiencies of scientific funding competitions

Carl T. Bergstrom,Kevin Gross

Allosteric regulation of a prokaryotic small Ras-like GTPase contributes to cell polarity oscillations in bacterial motility

Julien Herrou,Jyoti Baranwal,Manil Kanade,Pananghat Gayathri,Priyanka Rajendra Gade,Shrikant Harne,Sukanya Chakraborty,Sébastien Lhospice,Tam Mignot

Evolutionary change in the human gut microbiome: From a static to a dynamic view

Isabel Gordo

Control over single-cell distribution of G1 lengths by WNT governs pluripotency

Alex Chialastri,Daniel Bridges,Dasol Han,Guojing Liu,Jiwon Jang,Kenneth S. Kosik,Linda R. Petzold,Mahdi Golkaram,Morgane Audouard,Siddharth S. Dey,Stefan Hellander

Continued poxvirus research: From foe to friend

Susanna R. Bidgood

Trpm4 ion channels in pre-B？tzinger complex interneurons are essential for breathing motor pattern but not rhythm

Christopher A. Del Negro,Kaitlyn E. Dorst,Kaiwen Kam,Margaret S. Saha,Maria Cristina D. Picardo,Prajkta S. Kallurkar,Romain Guinamard,Ryoichi Teruyama,Victoria T. Akins,Xingru Ma,Yae K. Sugimura

Regulation plays a multifaceted role in the retention of gene duplicates

Christian R. Landry,Johan Hallin

Open notebook science can maximize impact for rare disease projects

Rachel J. Harding

Differential and convergent utilization of autophagy components by positive-strand RNA viruses

Emma Abernathy,Jan E. Carette,Karim Majzoub,Karla Kirkegaard,Nick van Buuren,Roberto Mateo,Sara W. Bird

A Notch-mediated, temporal asymmetry in BMP pathway activation promotes photoreceptor subtype diversification

Brice Ronsin,Elise Cau,Laurianne Bessière,Patrick Blader

CD4 occupancy triggers sequential pre-fusion conformational states of the HIV-1 envelope trimer with relevance for broadly neutralizing antibody activity

Alexandra Trkola,Branislav Ivan,Harini Subbaraman,Nikolas Friedrich,Zhaozhi Sun

Simu-dependent clearance of dying cells regulates macrophage function and inflammation resolution

Emma Louise Armitage,Hannah Grace Roddie,Iwan Robert Evans,Jonathon Alexis Coates,Simon Andrew Johnston

Dhh1 promotes autophagy-related protein translation during nitrogen starvation

Daniel J. Klionsky,Jun Hee Lee,Meiyan Jin,Sim Namkoong,Xu Liu,Zhangyuan Yin,Zhiyuan Yao

Molecular understanding of calcium permeation through the open Orai channel

Guangyan Wu,Jing Lu,Renci Ji,Xiaofen Liu,Xiaozhe Chen,Xin Li,Xing Zhang,Xue Yang,Yi Yu,Yuequan Shen

G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment

Amita Sehgal,Jeffrey M. Field,Joseph Bedont,Nicholas F. Lahens,Shirley Zhang,Yool Lee

Open science challenges, benefits and tips in early career and beyond

Christopher Allen,David M. A. Mehler

Artificially selecting microbial communities: If we can breed dogs, why not microbiomes?

Bj？rn Vessman,Flor I. Arias-Sánchez,Sara Mitri

Reversible association with motor proteins (RAMP): A streptavidin-based method to manipulate organelle positioning

Ambarish Kunwar,Amra Saric,Aritra Sen,Carlos M. Guardia,David A. Kolin,Juan S. Bonifacino,Michal Jarnik,Raffaella De Pace

The NIH public access policy did not harm biomedical journals

A. Townsend Peterson,Ada Emmett,Huijie Qiao,Josh Bolick,Marc L. Greenberg,Narayani Barve,Paul E. Johnson

Yeast α-arrestin Art2 is the key regulator of ubiquitylation-dependent endocytosis of plasma membrane vitamin B1 transporters

Henri-Fran？ois Renard,Jennifer Villers,Jér？me Savocco,Martine Prévost,Mathilde Bausart,Pierre Morsomme,Ruddy Wattiez,Sylvain Nootens,Wilhelmine Afokpa,Xiaoqian Chen

Prepontine non-giant neurons drive flexible escape behavior in zebrafish

Gregory D. Marquart,Harold A. Burgess,Kathryn M. Tabor,Kevin L. Briggman,Sadie A. Bergeron

Single-cell RNA sequencing reveals regulatory mechanism for trophoblast cell-fate divergence in human peri-implantation conceptuses

Bo Lv,Guoping Fan,Ping Lu,Qiao Zeng,Qin An,Xianmin Zhu,Xunyi Zhang,Yanqiu Wang,Yazhong Ji,Zhigang Xue

Symmetry breaking in the embryonic skin triggers directional and sequential plumage patterning

Camille Curantz,Carole Desmarquet-Trin Dinh,Jonathan Touboul,Magdalena Hidalgo,Marie Manceau,Richard Bailleul

Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins

Emily Hsieh,Georg Kochs,Harmit S. Malik,Janet M. Young,Laura Graf,Michael Emerman,Richard N. McLaughlin Jr,Rossana Colón-Thillet

A hormone receptor pathway cell-autonomously delays neuron morphological aging by suppressing endocytosis

Callista Yee,Claire E. Richardson,Kang Shen

Correction: MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

Amelie Fossoul,Bettina L. Lee,Craig E. Stivala,Dieter Demon,Filip Van Hauwermeiren,Irma B. Stowe,Jan Konvalinka,Libor Kostka,Lieselotte Vande Walle,Mohamed Lamkanfi,Nobuhiko Kayagaki,Pavel ？ácha,Pedro H. V. Saavedra,Petr ？imon,Sayumi Yamazoe,Steven T. Staben,Victoria C. Pham,Vladimír ？ubr

Waves of prediction

Karl J. Friston

New perspectives on the origins of the unique vocal tract of birds

Michael B. Habib

Language evolution and complexity considerations: The no half-Merge fallacy

Cedric Boeckx,Pedro Tiago Martins

A proposal for the future of scientific publishing in the life sciences

Bodo M. Stern,Erin K. O’Shea

Fat cells gobbling up norepinephrine?

Christoph Buettner,Vitaly Ryu

PlotsOfData—A web app for visualizing data together with their summaries

Joachim Goedhart,Marten Postma

©2008-2020 OALib, Inc | Public user content licensed CC-BY 4.0 unless otherwise specified. OALib ISSN Online: 2333-9721 OALib ISSN Print: 2333-9705